Renal classification

The antineoplastic dm are contraindicated in patients with leukopenia, thrombocytopenia, anemia, serious infections, serious renal disease, or known hypersensitivity to the drug and during pregnancy (see Display 55-1 for pregnancy classifications of selected antineoplastic drag s). 

The National Kidney Foundation (NKF) developed a classification system for CKD (Table 23-11.1 The staging system defines the stages of CKD based on GFR level, but also accounts for evidence of kidney damage in the absence of changes in GFR, as in stage 1 CKD. The GFR is calculated using the abbreviated Modification of Diet in Renal Disease (MDRD) study equation ... 

Racusen LC, Solez K, Colvin RB, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999 55 713-723. 

Dent s classification is the basis of most classifications of abnormal types of amino aciduria. He divides the pathological conditions into three categories (D9) (A) Overflow amino aciduriain which the blood level of the amino acid concerned is definitely raised above normal [example Section 4.2.1.L (a)] (B) Renal amino aciduria, in which case the blood level is either normal or below normal, and yet the urinary excretion is above normal [tubular reabsorption deficiency example Section 4.2.I.I. (e)] (C) No threshold amino aciduria, in which Dent attributes the condition to an extrarenal disturbance of the metabolism of an amino acid with a high blood clearance, and in which, on account of this latter circumstance, the corresponding blood level may stay normal or is hardly increased. 

In their communication the evidence is summarized suggesting two distinct types of dopamine receptors in the periphery, designated DA] and DA2. Goldberg and Kohli s classification is based primarily on in vivo results using the vasculature and flow of blood to the renal, femoral and other selected... 

Metallothioneins are evolutionarily conserved in that they contain a high cysteine content and lack of aromatic amino acids. However, few invertebrate MTs have been characterized, and these can exhibit wide variation in noncysteine amino acid residues. Initially, MTs were classified according to their structural characteristics. Class I MTs consist of polypeptides with highly conserved cysteine residue sequences and closely resemble the equine renal MT. Mammalian MTs consist of 61-68 amino acids residues and the sequence is highly conserved with respect to the position of the cysteine residues (e.g., cys-x-cys, cys-x-y-cys, and cys-cys sequences, where x and y are noncysteine, non-aromatic amino acids). Class II MTs have less conserved cysteine residues and are distantly related to mammalian MTs. Class III MTs are defined as atypical and consist of enzymatically synthesized peptides such as phy-tochelatins and cadystins. This former classification scheme has been replaced by a more complex system to include the increasing number of identified isoforms. 

Tumor classification by tissue microarray profiling random forest clustering applied to renal cell carcinoma. 

Diuretic drugs their sites and modes of action, classification, adverse effects and uses in cardiac, hepatic, renal and other conditions... 

The adverse effects of cardiac glycosides can be cardiac or non-cardiac. They mostly occur through toxicity and are time-independent (DoTS classification) susceptibility factors include electrolj4e abnormalities (particularly hypokalemia), renal insufficiency, and age. 

Waikar SS, Curhan GC, Wald R, McCarthy EP, ChertowGM. Declining mortality in patients with acute renal failure, 1988 to 2002 KnaussWA Apache II a severity of disease classification system, Crit Care Med 1985 13 818-829],... 

The serum zinc level of the alcoholic subjects tends to be lower in comparison with the controls. An absolute increase in renal clearance of zinc in the alcoholics demonstrable at both normal level and low serum zinc concentration has been observed (32). Thus the measurement of renal clearance of zinc may be clinically used for etiological classification of chronic liver disease attributable to alcohol in diflFerent cases. 

Mehta RL, Chertow GM. Acute renal failure definitions and classification time for change J Am Soc Nephrol 2003 14 2178-87. 

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