Recent insights

27 Fracture surface for AM30 in distilled water under CERT conditions showing zones corresponding to iocalised dissoiution, see and inert fracture [70]. 

28 Micrograph of secondary crack in AZ91 tested distilled water at 3 X 10 s showing crack nucleation within a 3 particle. 

30 Fracture surface morphology for AZ91 in distilled water at 3 x 10 s showing quasi-porous features [70]. 

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The discussion of the catalytic, asymmetric variants will incorporate a significant emphasis on the interplay of mechanistic investigations and synthetic optimization studies to provide a unified picture of the cyclopropanation methods. Finally, recent insights provided by computational analysis of the transition structures for cyclopropanation will be discussed. 

Betz H, Laube B (2006) Glycine receptors recent insights into their structural organization and functional diversity. JNeurochem 97 1600-1610... 

One of the most significant recent insights in surface chemical dynamics is the idea that the principle of detailed balance may be used to infer the properties of a dissociative adsorption reaction from measurements on an associative desorption reaction.51,52 This means, for example, that the observation of vibrationally-excited desorption products is an indicator that the dissociative adsorption reaction must be vibrationally activated, or vice versa the observation of vibrationally-cold desorption products indicates little vibrational promotion of dissociative adsorption. In this spirit, it is... 

Early natural product research with marine mollusks supported a conclusion that all secondary metabolites of mollusks are diet-derived, which proved to be premature. In fact, the biosynthetic capability of some marine mollusks covers a wide spectrum of chemical classes and substances. Much of this recent insight has resulted from work in the laboratories of the authors of Chapter 3. 

Distelhorst, C. W. Recent insights into the mechanism of glucocorticosteroid-induced apoptosis. Cell Death Differ. 9 6-19, 2002. 

T. D. Heightman, A T. Vasella, Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases , Angew. Chem. Int. Ed. 1999, 38,750-770. 

Kadlubar FF. Biochemical individuality and its implications for drug and carcinogen metabolism recent insights from acetyltransferase and... 

A. C. Storer, R. Menard, Recent Insight into Cysteine Protease Specificity Lessons for Drug Design , Perspect. Drug Discov. Design 1996, 6, 33 - 46. 

Wood M, Stambler B, Ellenbogen K. Recent insights in programmed electrical stimulation for the management of sustained ventricular arrhythmias. Curr Opin Cardiol. Jan 1994 9(1) 3-11. 

This mathematical model is only fitting as long as atomic nuclei can be considered achiral. In fact, this is not true because of the electroweak interaction. The consequence is an energy difference of enantiomers on the order of 10 17 J/ mol. For an excellent account of these recent insights see S. Mason, Chem. Soc. Rev. 17, 347-359 (1988). 

Holmes A, Lachowicz JE, Sibley DR Phenotypic analysis of dopamine receptor knockout mice recent insights into the functional specificity of dopamine receptor subtypes. Neuropharmacology 2004 47 1117. [PMID 15567422]... 

Sutton, M.D., Smith, B.T., Godoy, V.G., Walker, G.C. (2000) The SOS response recent insights into umuDC-dependent mutagenesis and DNA damage tolerance. Annu. Rev. Genet. 34, 479-497. 

Praziquantel was developed in the late 1970s (Gonnert and Andrews, 1 977) and tested in humans soon after (Katz et al., 1979 Santos et al., 1979). It has been identified by the World Health Organization (WHO) as the drug of choice for the treatment of schistosomiasis caused by S. mansoni, S. japonicum or 5. haematobium since 1982 (Andrews et al., 1983). The mechanism of praziquantel s anti-schistosomal activity remains unclear, but recent insights are reviewed in Chapter 14. More information about other uses for praziquantel for other flatworm diseases can be found in Chapter 12. 

Lohmeier TE, Hildebrandt DA, Warren S, et al. Recent insights into the interactions between the baroreflex and the kidneys in hypertension. Am J Physiol Regul Integr Comp Physiol. 2005 288 R828-R836. 

Benowitz NL, Hansson A, Jacob P, 3rd (2002) Cardiovascular effects of nasal and transdermal nicotine and cigarette smoking. Hypertension 39 1107-12 Berretta N, Jones RSG (1996) Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex. Neuroscience 75 339 Betz H, Laube B (2006) Glycine receptors recent insights into their structural organization and functional diversity. J Neurochem 97 1600-10... 

Venus and Titan have been upgraded to Category II in Schulze-Makuch and Irwin (2004) due to recent insights on their dynamic activity, planetary/lunar history, and presence of organic compounds. 

It is a surprisingly recent insight - only about 100 years old. (OK, so that is relative - long ago for you, but I m nearly there.)... 

Burgess AW, Cho H-S, Eigenbrot C, Ferguson KM, Lemmon MA, Sliwkowski MS, Ward CW, Yokoyama S. An open-and-shut case Recent insights into the activation of EGF/ErbB receptors. Mol. Cell. 2003 12 541-552. 

Heightman, T D, Vasella, A T, Recent insights into inhibition, stmcture, and mechanism of configuration-retaining glycosidases, Angew. Chem., Int. Ed., 38, 750-770, 1999. 

Leavitt BR, Wellington CL, Hayden MR. Recent insights into the molecular pathogenesis of Hunting-ton disease. Semin Neurol 1999 19 385-95. 

Nancollas GH, Johnsson MAS Calculus formation and inhibition. Adv Dent Res 1994 8 307-311. White DJ Dental calculus recent insights into occurrence, formation, prevention, removal and oral health effects of supragingival and subgingival deposits. Eur J Oral Sci 1997 105 508-522. Pattanapom K, Navia JM The relationship of dental calculus to caries, gingivitis, and selected salivary factors in 11- to 13-year-old children in Chiang Mai, Thailand. J Periodontal 1998 69 955-961. 

Reconstructing Science Dscovery and Experiment , in D. Batens and J. P. V. Bendegem (eds). Theory and Experiment Recent Insights and Perspectives on Their Relation (Dordrecht D. Reidel, 1988), pp. 33-53. 

H.C. Chen and R.V. Farese, Fatty acids, triglycerides, and glucose metabolism recent insights from knockout mice, Curr. Opin. Clin. Nutr. Metab. Care, 2002, 5, 359-363. 

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