Ranitidine interaction

Pharmacokinetic evidence su ests that neither cimetidine nor ranitidine interact with isoniazid. 

Other studies clearly confirm that cimetidine causes a very significant rise in plasma nifedipine levels and an increase in its effects, whereas ranitidine interacts only minimally. " ... 

Janssen Pharmaceuticals. Cisapride-ranitidine interaction. Data on file (Study R 51 619/74), 1986. 

Fernandes E, Melewicz FM Antacids and theo Jiylline-ranitidine interaction Am Intern Med (1984)101,279. 

Cukier A Vaigas FS, Santos SRCJ, Donzella H, Terra-Filho M, Teixeira L Light RW. Theophylline-ranitidine interaction in elderly COPD patients. BrazJMedBidRes (1995) 28, 875-9. 

Ranitidine 61 Moderate 9 Fa calculated from Fa — F/(l — CLh/Qh). Interaction with transporters... 

Rendic, S., Ruf, S., Weher, P. and Kajfez, F. (1984). Cimetidine and ranitidine Their interaction with human and pig liver microsomes and with purified cytochrome P-450. Eta J. Drug Metab. Pharmacokinet. 9 195-200. 

Ranitidine is a H2-receptor antagonist, which reduces the gastric output. Unlike cimetidine, ranitidine does not interact with cytochrome P450, so does not retard hepatic metabolism of certain drugs, such as warfarin. Ranitidine may be administered as 150 mg twice daily or 300 mg at night. 

Drugs that may interact with alendronate include ranitidine and aspirin. Drugs that may interact with tiludronate include aspirin and indomethacin. Calcium... 

Drug/Lab test interactions False-positive tests for urobilinogen may occur during nizatidine therapy. False-positive tests for urine protein with Multistix may occur during ranitidine therapy testing with sulfosalicylic acid is recommended. 

Drug/Food interactions Food may increase bioavailability of famotidine and nizatidine this is of no clinical consequence. Cimetidine and ranitidine are not affected. 

Deravirdine (Rescnptor) [Antiretroviral/NNRTI] Uses HIV Infxn Action Nonnucleoside RT inhibitor Dose 400 mg PO tid Caution [C, ] CDC recommends HIV-infected mothers not to breast-feed (transmission risk) w/ renal/hepatic impair Contra Use w/ drugs dependent on CYP3A for clearance (Table VI-8) Disp Tabs SE Fat redistribution, immune reconstitution synd, HA, fatigue, rash, T transaminases, N/V/D Interactions T Effects W/ fluoxetine T effects OF benzodiazepines, cisapride, clarithromycin, dapsone, ergotamine, indinavir, lovastatin, midazolam, nifedipine, quinidine, ritonavir, simvastatin, terfena-dine, triazolam, warfarin effects W/ antacids, barbiturates, carbamazepine, cimetidine, famotidine, lansoprazole, nizatidine, phenobarbital, phenytoin, ranitidine, rifabutin, rifampin effects OF didanosine EMS Use of benzodiazepines and CCBs should be avoided may cause a widespread rash located on upper body and arms OD May cause an extension of nl SEs symptomatic and supportive Deferasirox (Exjade) [Iron Chelator] Uses Chronic iron overload d/t transfusion in pts >2 y Action Oral iron chelator Dose Initial 20 mg/kg... 

T Pancreatic insulin release Metformin Peripheral insulin sensitivity hepatic glucose output/production i intestinal glucose absorption Dose Ist-line (naive pts), 1.25/250 mg PO daily-bid 2nd-line, 2.5/500 mg or 5/500 mg bid (max 20/2000 mg) take w/ meals, slowly T dose hold before 48 h after ionic contrast media Caution [C, -] Contra SCr >1.4 mg/dL in females or >1.5 mg/dL in males hypoxemic conditions (sepsis, recent MI) alcoholism metabolic acidosis liver Dz Disp Tabs SE HA, hypoglycemia, lactic acidosis, anorexia, N/V, rash Additional Interactions T Effects W/ amiloride, ciprofloxacin cimetidine, digoxin, miconazole, morphine, nifedipine, procainamide, quinidine, quinine, ranitidine, triamterene,... 

Clinicians should be aware of a few drug interactions with Zolpidem. Flumazenil acts as an antagonist to the hypnotic effects of zolpidem. There is decreased alertness when zolpidem is combined with cimetidine. There is an increase in anterograde amnesia in volunteers treated with a combination of imipramine and zolpidem. Haloperidol, ranitidine, chlorpromazine, warfarin, and digoxin, along with cimetidine and flumazenil, do not alter the pharmacokinetics of zolpidem (Salva and Costa, 1995). 

Drug Interactions Gemfibrozil Niacin Erythromycin Cholestyramine Digoxin Cimetidine/ranitidine/ omeprazole Rifampicin Warfarin Itraconazole Gemfibrozil Niacin Erythromycin Propranolol Digoxin Warfarin Antacids Colestipol Digoxin Erythromycin Oral contraceptives Fibrates Niacin Azole antifungals... 

---