Quadriceps femoris muscles

Figure 2. Force generation and energy metabolism in human quadriceps femoris muscle stimulated intermittently at 20 Hz, with 1.6 sec tetani with 1.6 sec rest periods between tetani. The upper panel shows force, ATP turnover rate, and pH the middle panel, the concentrations of PCr, P and lactate and the lower panel, ATP, ADP, IMP, H, and calculated H2PO4. From Hultman et al. (1990), with permission from Human Kinetics Publishers.

Intramuscular injections. Generally, intramuscular injections are made with small gauge needles into the epaxial muscles on either side of the lumbar vertebral column or the quadriceps femoris muscle on the ventral side of either rear leg. Due to the small size of mice, very small volumes (e.g., 0.05 mL) should be injected. 

The time course of use and replenishment of creatine is shown in the study of exercising human subjects reported in Figure 4.36, The subjects exercised on a stationary bicycle that was adjusted so that exhaustion would be reached after 6 minules. Muscle biopsies, taken before and after exercise, from the quadriceps femoris muscle of the leg were used for analysis of cneatine-P The data demonstrate that the reservoir of creatine-P, substantially depleted by the end of the exercise period, was rapidly repleted during the subsequent resting period. 

FrCiURE 4.36 Creiitine phosphate concern rations before and after OKencise. Human subjects exercised on a stationary bJeycIc, adjusted SO that exhaustion was reached after 6 min. Muscle biopsies, taken from the quadriceps femoris muscle of the leg, were used for analyses of creatine phosphate. (Redrawn with permission from Harris ct u/., 1976.)... 

Mase Jr., V.J., Hsu, J.R., Wolf, S.E., Wenke, J.C., Baer, D.G., Owens, J., Badylak, S.F., Walters, T.J., 2010. Clinical application of an acellular biologic scaffold for surgical repair of a large, traumatic quadriceps femoris muscle defect. Orthopedics 33, 511. 

Kinugasa R, Watanabe T, Ijima H et al. (2006) Effects of vascular occlusion on maximal force, exercise-induced T2 changes, and BMG activities of quadriceps femoris muscles. Int J Sports Med 27, 511-516. 

In the lower limbs the quadriceps femoris muscles are most severely affected and undergo progressive atrophy, particularly of the vastus medialis and lateralis, with relative sparing of the rectus femoris (Figure 9.2). As in the upper limbs the weakness is often more severe on the nondominant side. Weakness of the ankle dorsiflexors is also common but severe foot-drop occurs infrequently. Other muscle groups such as the hip extensors and abductors and ankle plantar flexors are usually only mildly affected. 

Figure 4 Neuromusclar stimulation of the quadriceps femoris muscles.

Jakobsson P, Jordfelt I, Henriksson J. Metabolic eirzyme activity in the quadriceps femoris muscle in patients with severe COPD. Am J Respir Crit Care Med 1995 151 374-377. 

Selkowitz DM. Improvement in isometric strength of the quadriceps femoris muscle after training with electrical stimulation. Phys Ther 1985 65 186-196. 

Lewek M, Stevens J, Snyder-Mackler L. The use of electrical stimulation to increase quadriceps femoris muscle force in an elderly patient following a total knee arthroplasty. Phys Ther 2001 81(9) 1565-1571. 

Lewek MD, Rudolph KS, Snyder-Mackler L (2004) Quadriceps femoris muscle weakness and activation failure in patients with symptomatic knee osteoarthritis. J Orthop Res 22 110-115... 

The anterior compartment of the thigh includes the sartorius and the quadriceps femoris muscle. Addi-... 

Protein metabolism Cortisol promotes the breakdown of proteins and inhibits protein synthesis. This leads to muscle wasting in the quadriceps-femoris groups, and muscular activities may become difficult as a result. The effect of cortisol is opposite to that of insulin. 

To determine the effects of GA on different tissues, the following tissues were examined, namely, liver (L), kidney (K), visceral and subcutaneous adipose tissues (VAT and SAT), quadriceps femoris (QF), and abdominal muscles (AM). 

The quadriceps femoris consists of four muscles of the anterior thigh. These knee extensor muscles are, perhaps, the most significant. Weakened quadriceps muscles decrease the stability of the knee and make it more prone to injury. 

Slowly progressive muscle weakness and atrophy selective pattern with quadriceps femoris and finger flexors affected first, followed by other muscle groups frequently asymmetric and more severe on nondominant side... 

Fig. 1. Concentration of radioactivity in rat tissues after single subcutaneous injection of 0.098 /ig (11.5 ftC) of estradiol-6,7- H in 0.5 ml of saline. Liver and kidney points are mean values of 3 aliquots of dried pooled tissue other points are median values of individual samples from 6 animals. Muscle is M. quadriceps femoris. From Jensen and Jacobson (1962).

A muscle consists of groups of muscle bundles that join into a tendon at each end. The muscle bundles in the quadriceps are the vastus medialis, rectus femoris, vastus inter-medialis and vastus lateralis. Each bundle is separately wrapped in a sheath of connective tissue. Each muscle is composed of many fibres, packaged into bundles of about... 

Fig. 13.2a-c Normal quadriceps muscle, a-c Schematic drawings of a coronal view through the anterior thigh showing the muscle bellies forming the quadriceps from deep (a) to superficial (c). a,b The vastus intermedius (VI) is the deepest muscle. On each side, it is partially covered by the vastus lateralis (VX) and the more distal vastus medialis (VM). c The rectus femoris (RF) is located more superficially. It arises from a direct (DT) and an indirect (IT) tendon from the anterior inferior iliac spine and inserts into a long flat tendon (asterisk) that forms the superficial layer of the quadriceps tendon... 

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