Propyl 4-hydroxybenzoate sodium salt

Synonyms E217 propyl 4-hydroxybenzoate sodium salt sodium propyl hydroxybenzoate soluble propyl hydroxybenzoate. 

See Potassium propylparaben Propyl-4-hydroxybenzoate, sodium salt Propyl-p-hydroxybenzoate, sodium salt. See Sodium propylparaben... 

Synonyms p-Hydroxybenzoic acid, propyl ester, sodium deriv. 4-Hydroxybenzoic acid, propyl ester, sodium salt Propyl-4-hydroxybenzoate, sodium salt Propyl-p-hydroxybenzoate, sodium salt Propylparaben sodium Propylparaben sodium salt Sodium 4-propoxycarbonylphenoxide Sodium propyl 4-hydroxybenzoate Sodium propyl p-hydroxybenzoate... 

Propyl parasept 4-hydroxybenzoic acid propyl ester Propyl parahydroxybenzoate Propylparaben Nipasol M E 216 (sodium salt E 217). 

Applications. In many countries the methyl, ethyl and n-propyl esters of p-hydroxybenzoic acid, as well as their sodium salts, are permitted for preservation of some foods. The maximum permissible quantity is around 0.1%. In the USA methyl- and propyl-paraben are considered GRAS. The maximum permissible quantity is 0.1%. Their main field of use is not food preservation but the preservation of pharmaceutical and cosmetic fat emulsions. The usage of the butyl ester is not allowed in food applications. 

Boil about 01 g with 50 ml of N sodium hydroxide for thirty minutes under reflux. Cool, add 50 ml of 01N bromine and 10 ml of concentrated hydrochloric acid. Allow to stand for half an hour, shaking repeatedly during the first fifteen minutes, add 2 g of potassium iodide and titrate the liberated iodine with O IN sodium thiosulphate. 1 ml of 0 1 N bromine == 0 002536 g methyl hydroxybenzoate, CgHgOa 0 002902 g sodium salt of the methyl ester 0 003003 g propyl hydroxybenzoate, C10H12C3, and 0 003370 g sodium salt of the propyl ester. 

Prochlorperazine Edisylate Prochlorperazine edisylate is not compatible with sodium chloride solutions containing methyl hydroxybenzoate and propyl hydroxy-benzoate as preservatives, but is compatible with solutions containing benzyl alcohol. Prochlorperazine edisylate salts are incompatible with a number of drugs such as aminophylline, amphotericin, ampicillin sodium, some barbiturates, ben-zylpenicillin salts, calcium gluconate, cefmetazole sodium, cephalothin sodium, chloramphenicol sodium succinate, chlorothiazide sodium, chloramphenicol, morphine sulfate containing phenol, magnesium trisilicate mixture, sodium succinate, chlorothiazide sodium, dimenhydrinate, heparin sodium, hydrocortisone sodium succinate, midazolam hydrochloride, and some sulfonamides.166... 

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