3- propanol preparation

Show reagents and experimental conditions that can be used to synthesize these compounds from 1-propanol (any derivative of 1-propanol prepared in an earlier part of this problem may be used for a later synthesis) (See Examples 8.5, 8.6, 8.9, 8.10)... 

Dilute the sample in water so that the ethyl alcohol concentration is about 1 per cent. Add to this solution 1 per cent of w-propanol. Prepare... 

Tertiary butyl alcohol, trimethyl carbinol, tertiary butanol. 2-methyl-2-propanol, Me3COH. Colourless prisms, m.p. 25°C, b.p. 83°C. Prepared by absorbing isobutene (2-methylpropene) in sulphuric acid, neutralizing and steam distilling the liquor. Converted to isobutene by heating with oxalic acid. Potassium-/-buloxide is a very strong base. 

Glycerol -dichlorohydrin, 2.3-dichloro-propanol, CH2CI CHC1 CH2 0H. Colourless liquid, b.p. 182 C. Prepared by the chlorination of propenyl alcohol. Oxidized by nitric acid to 1,2-dichloropropionic acid. Reacts with NaOH to give epichlorohydrin. 

Figure Bl.19.32. AFM image of Blue Seript II plasmid (400 mu x 400 mu) in propanol, taken with super tip , prepared by earbon deposition on nomral tip in SEM, followed by ion milling. (Taken from [152], figure 1.)...

Does the NMR spectrum shown in Figure 22 10 correspond to that of 1 amino 2 methyl 2 propanol or to 2 ammo 2 methyl 1 propanoD Could this compound be prepared by reaction of an epoxide with ammonia" ... 

PVF has low solubdity in all solvents below about 100°C (61). Polymers with greater solubdity have been prepared using 0.1% 2-propanol polymerization modifier and were characterized in /V, /V- dim ethyl form am i de solution containing 0.1 AlLiBr. ranged from 76,000 to 234,000... 

HVP products prepared by hydrolysis with HCl contain varying amounts of glycerol chlorohydrins, such as 3-chloro-l,2-propanediol [96-24-2] and l,3-dichloro-2-propanol [96-23-1J, depending on reaction conditions and Hpid contents of the starting material (135). As a result of their toxicides, regulating agencies in many countnes have restncted the contents of these compounds in food. 

Docusate Calcium. Dioctyl calcium sulfosuccinate [128-49-4] (calcium salt of l,4-bis(2-ethylhexyl)ester butanedioic acid) (11) is a white amorphous soHd having the characteristic odor of octyl alcohol. It is very slightly soluble in water, and very soluble in alcohol, polyethylene glycol 400, and com oil. It may be prepared directly from dioctyl sodium sulfo succinate dissolved in 2-propanol, by reaction with a methan olic solution of calcium chloride. 

MMA and MAA can be produced from ethylene [74-85-1/ as a feedstock via propanol, propionic acid, or methyl propionate as intermediates. Propanal may be prepared by hydroformylation of ethylene over cobalt or rhodium catalysts. The propanal then reacts in the Hquid phase with formaldehyde in the... 

Many members of this series are known based on nitroparaffin condensations with aldehydes of longer chain length than formaldehyde. However, only the five primary amino alcohols discussed in the following are manufactured on a commercially significant scale. N-Substituted derivatives of these compounds also have been prepared, but only 2-dimethylamino-2-methy1-1-propanol has been available in commercial quantities (Table 1). 

Eatty amine oxides are most frequendy prepared from alkyldimethylarnines by reaction with hydrogen peroxide. Aqueous 2-propanol is used as solvent to prepare amine oxides at concentrations of 50—60%. With water only as a solvent, amine oxides can only be prepared at lower concentrations because aqueous solutions are very viscous. Eatty amine oxides are weak cationic surfactants. 

Halogenated 2-propanol derivatives, eg, l,3-dichloro-2-propanol [96-23-1], are generally prepared from glycerol [56-81-5] (qv). These materials are used in the preparation of halogen-containing phosphates to plasticize and lower the flammability of plastics, eg, polyurethanes and ceUulosics. 

Block copolymers of vinyl acetate with methyl methacrylate, acryflc acid, acrylonitrile, and vinyl pyrrohdinone have been prepared by copolymeriza tion in viscous conditions, with solvents that are poor solvents for the vinyl acetate macroradical (123). Similarly, the copolymeriza tion of vinyl acetate with methyl methacrylate is enhanced by the solvents acetonitrile and acetone and is decreased by propanol (124). Copolymers of vinyl acetate containing cycHc functional groups in the polymer chain have been prepared by copolymeriza tion of vinyl acetate with A/,A/-diaIlylcyanamide and W,W-diaIl5lamine (125,126). 

International Specialty Products (ISP) suppHes ethyl, isopropyl, and -butyl half-esters of PMVEMA as 50% solutions in ethanol or 2-propanol. Typical properties are shown in Table 8. These half-esters do not dissolve in water but are soluble in dilute aqueous alkaU and in aqueous alcohoHc amine solutions. The main appHcation for the half-esters is in hairsprays where they combine excellent hair-holding properties at high humidity without making the hair stiff or harsh. These half-esters are easily removed during shampooing, have a very low order of toxicity, and form tack-free films that exhibit good gloss, luster, and sheen (see Hair preparations). 

PZN-PT, and YBa2Cug02 g. For the preparation of PZT thin films, the most frequently used precursors have been lead acetate and 2irconium and titanium alkoxides, especially the propoxides. Short-chain alcohols, such as methanol and propanol, have been used most often as solvents, although there have been several successful investigations of the preparation of PZT films from the methoxyethanol solvent system. The use of acetic acid as a solvent and chemical modifier has also been reported. Whereas PZT thin films with exceUent ferroelectric properties have been prepared by sol-gel deposition, there has been relatively Httle effort directed toward understanding solution chemistry effects on thin-film properties. 

Cyclopropyl-1 lodo-2-propanol (6). To freshly scraped samanum powder (300 mg, 2 at) at O C was added a few drops of a solution of 4 (34 mg, 1 mmol) and 5 (803 mg, 3 mmol), in THF (6 mL). After initiation, the rest was added with stirring dunng 20 min, end after 20 min at 0°C, the mixture was treated with 1 N HCI and extracted with ether. The combined extracts were washed with aq Na2S203 solution and brine, and dned over MgSOs Evaporation and preparative TLC gave 175 mg of 6 (77%)... 

Similar procedures have been used in preparing other 2-alkylaminoethanols and N-alkyl derivatives of l-amino-2-pro-panol, 2-amino-l-propanol, 3-amino-l-propanol, 2-amino-l-bu-tanol, and l-amino 2-methyl-2-propanol. ... 

This dialkoxydiphenylsulfurane has been prepared by the reaction of diphenyl sulfide, 2,2,2-trifluoro-l-phenyl-l-(trifluoromethyl)ethyl hypochlorite, and potassium l,l,l,3,3,3-hexafluoro-2-phenyl-2-propanolate and by the reaction of diphenyl sulfide with 1 equivalent of chlorine and 2 equivalents of potassium 1,1,1,3,3,3-hexafluoro-2-phenyl-2-propanolate in diethyl ether. ... 

A recent study of the reduction of cholest-4-en-3-one with an excess of NaBH4 in 2-propanol shows that the corresponding cholest-4-en-3 -ol is the major product (44% yield) 4 other compounds (5a-cholestan-3a- and -3jS-ols, a sterol, possibly 5y -cholestan-3l -ol and an unidentified hydrocarbon) have also been isolated. When the reduction is carried out in the presence of ultraviolet light cholest-4-en-3/5-ol is still the major product (34%) but 7 other products are also obtained. These results show clearly the benefit of using Li[OC(CH3)3]3AlH for the preparation of the 4-en-3 -ol. ... 

As a second exanple, consider the preparation of l-bromo-2-methyl-2-propanol from rcrr-butyl alcohol. 

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