Process synthesis future

Computer-aided process synthesis systems do not mean completely automated design systems (57). Process synthesis should be carried out by interactive systems, in which the engineer s role is to carry out synthesis and the machine s role is to analy2e the performance of synthesized systems. Computet apphcations in the future will probably deal with the knowledge-based system in appHed artificial intelligence. Consequendy, research on computer-aided process synthesis should be directed toward the realization of such systems with the collaboration of experienced process engineers. 

Latin hypercube Hammersley sequence sampling (LHSS), 26 1013-1015 Latin hypercube sampling (LHS), 26 1005, 1007-1011, 1012, 1013, 1014, 1015 future trends in, 26 1047 in process synthesis and design,... 

Monte Carlo sampling, 26 999, 1001—1004 in control systems, 26 1046 future trends in, 26 1047-1048 HSGA algorithm and, 26 1032 in process scheduling, 26 1042-1043 in process synthesis and design, 26 1041 quasi-Monte Carlo sampling and, 26 1011-1016 for risk analysis, 26 1045 in supply chain management, 26 1043-1044... 

Romagnoli LG, Knorr D (1988) Effects of ferulic acid treatment on growth and flavor development of cultured Vanilla planifolia cells. Food Biotechnol 2 93-104 Schrader J, Etschmann MMW, Sell D, Hilmer J-M, Rabenhorst J (2004) Applied biocatalysis for the synthesis of natural flavour compounds—current industrial processes and future prospects. Biotechnol Lett 26 463-472... 

The principle of integral process development [26] covers much more than just the optimization of a process. This approach begins with computer-aided decision procedures in the conception phase. Tools are available in which the process structure is suggested, for example should the process be a batch or a continuous operation The software tool for process synthesis PROSYN uses databases which include knowledge of experts, material data and calculation models for unit operations. Interfaces to process simulation tools such as ASPENPLUS and material databases are also supplied. PROSYN also delivers an economic evaluation of the future production process. 

All of the chapters develop highly successful synthesis methods for their respective cutting-edge applications. Nevertheless, they also highlight many unresolved issues in process synthesis and give guidelines for future research. As a result, there are still many challenging research issues in this active field. It is our hope that this volume points these out and spurs future research in this area. 

This entry presents the structure of computer-aided process engineering (CAPE) from the perspective of activities, problems, and methods. More detailed information is presented on process synthesis and chemical product development. Future prospects of process and product design are mentioned briefly. 

Optimal process synthesis Two problems (a) chemical process optimization for maximization of net present value (NPV) while minimizing uncertainty in the future demand of two products, and (b) utility system optimization for minimization of both total annual cost and CO2 emission. Multi-Criteria Branch and Bound (MCBB) Algorithm The existing MCBB algorithm was modified to increase speed, reliability and suitahility for a wide range of applications. Mavrotas and Diakoulaki (2005)... 

Several of the review papers referenced at the end of this chapter point out the future needs and directions of research in process synthesis. Some of the recommendations for areas for further work in separation processes are summarized below ... 

Simple and conventional catalytic synthesis method and stoichiometric organic or inorganic synthesis methods have an economic advantage as industrial process to compare with conventional electrochemical synthesis methods. A serious disadvantage of electrochemical method is complicated cell structure and components. Thus, excellent performances of product yield and selectivity by using unique electrocatalysis is essential to achieve a new green and sustainable electrochemical process in future. 

In this chapter, we have summarized striking examples of cascade reactions for the chemo-enzymatic synthesis of glycoconjugates. The benefit of cascade reactions without intermediate product work-up is emerging in the field of glycan synthesis. Future studies should be therefore directed toward biocatalyst engineering and process design to match the requirements for sequential, one-pot, and convergent cascade reactions. 

J. (2004) Applied biocatalysis for the synthesis of natural flavor compounds - current industrial processes and future prospects. Biotechnol. Lett, 26, 463-472. 

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