Preparation Guidelines

As mentioned before, the execution plan and master schedule go hand in hand with the cost estimate. Neither can be completed without the other. The project 

If one worker requires ten days to perform one activity, it may be argued that ten workers could perform it in one day. Unfortunately, that is not the case in project execution all projects involve hundreds, even thousands, of activities, many of which must be performed sequentially. If the activities to be performed in ten days were ten sequential ones instead of a single activity, ten workers could not perform them in one day. More likely, they would perform them in three or four days expending thirty or forty man-days instead of ten. The shortest possible schedule is dictated by the longest string of sequential activities as well as the minimum chronological time and labor hours required to perform each one. The duration of the construction effort is dependent on a number of factors  

A firm Execution Plan cannot be firmed up until  

However, the preparation of execution plans is a bootstrap operation, where a preliminary plan must first be developed to make the execution decisions, which in turn may impact the original data and determine the firm execution plan. The information required to prepare a preliminary project execution plan is essentially the same as that required for the initial plan of action discussed in Chapter 5, except that it is now based on more accurate data. Whereas the latter is based on conceptual data and educated guesses, the preliminary execution plan must reflect, at least, a Phase 0 design and a preliminary or conceptual cost estimate. 

The annotated equipment list developed in the Phase 0 design (see equipment list and cost estimate in Appendix L) will permit the Project Manager to prepare, as indicated in Section 19.1 a conceptual cost estimate including  

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Prepare guidelines for thermal hazard assessment and prevention. 

Regulatory authorities such as the FDA have prepared guidelines on comparability protocol, Comparability Protocols—Chemistry, Manufacturing and Controls Information, to enable manufacturers to follow a plan to establish and substantiate that changes to postapproval processes do not affect drug quality. 

Proposers are strongly encouraged to consult the proposal submission checklist included in the Grant Proposal Guide as they prepare their proposal. Proposals not compliant with the proposal preparation guidelines, as supplemented by the following instructions, may be returned without review. 

Understand Submission Guidelines. Each FDA Center has specific guidelines that must be followed for successful submission. Table 1.1 contains links to Center-specific preparation guidelines and contacts. Table 1.2 lists electronic submissions supported by the FDA ESG. Important information on the use of digital/electronic signatures on FDA forms can be found in Appendix C, Digital Signatures. 

The Committee recommended that WHO prepare guidelines for the labelling of pesticides for public health use, which should be harmonized with the FAO guidelines on good labelling practice (72) while taking into consideration other international guidelines. 

For statistical analysis it is necessary to prepare and to measure each standard at least twice. In routine analysis, carried out according to carefully prepared guidelines, confidence limits are P = 0.95, based on the standard distribution. In all other cases, especially in solving discrepancies between analytical results or for preparing instructions, confidence limits of F = 0.95 or F = 0.99, based on the t distribution, are used. The confidence intervals decrease somewhat more as the number of measurements increases, up to about 6. Above this number the effect is negligible. It can be shown that at a given number of measurements the confidence limit of the final result will be at its minimum if the number of calibration standards equals the number of sample measurements (Weitkamp and Barth, 1976). 

Handling, Storage, and Precautions best used as prepared. Guidelines for the handling of air- and moisture-sensitive materials should be followed. ... 

Thoughts on Scheduling Influential Factors Preparation Guidelines... 

That physicians and pharmacists jointly study the appropriateness of the quantity of drugs on a prescription and prepare guidelines. 

Just what information is required in RIA, and what techniques are required to produce those data for each affected agency remain unclear. At the time of writing this paper, it was generally understood that EPA and other affected agencies were preparing guidelines for preparation of RIAs that would afford additional insight into their approach to these documents. 

The techniques for measurement of photosynthesis in sediments and in macrophytes are less standardised. In a SCOR-workinggroup (UNESCO, 1973) an attempt was made to prepare guidelines for the measurement of... 

WHO has prepared guidelines [17] for in vivo activation analyses in 1977 that limit the dose to the general public to an average of 1 mSv and not exceeding 3 mSv. 

Aseptic National Preparation in class A background preparation guideline class D At each batch extent depending on risk assessment Environmental monitoring Depending on characteristics radiochemical/ radiopharmaceutical validation of labelling limited product dossier... 

Buhlmann X, Gay M, Gubler HU, Hess H, Kabay A, Knusel F, Sackman W, Schiller I, Urban S (1972) Microbiological quality of pharmaceutical preparations. Guidelines and methods. Am J Pharm Sci Support Public Health 144 165-186... 

The authors propose that these models can be used as tools for preparing guidelines for choosing protective clothing in hot and humid environments. 

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