Preparation drying step

Transparent monoliths can be prepared by drying high density gels (49,50). Control of initial conditions of sol preparation is essential to achieve success during the drying step. 

Ruthenium-copper and osmium-copper clusters (21) are of particular interest because the components are immiscible in the bulk (32). Studies of the chemisorption and catalytic properties of the clusters suggested a structure in which the copper was present on the surface of the ruthenium or osmium (23,24). The clusters were dispersed on a silica carrier (21). They were prepared by wetting the silica with an aqueous solution of ruthenium and copper, or osmium and copper, salts. After a drying step, the metal salts on the silica were reduced to form the bimetallic clusters. The reduction was accomplished by heating the material in a stream of hydrogen. 

Recovery — Recovery control (RC) solutions were prepared in 10/90 v/v ACN/water. Recovery evaluation (RE) samples were prepared in human plasma. Aliquot of RC solutions into assay plates followed sample preparation procedure steps 1 and 2. Instead of adding 50 pL of diluent, wells containing RC solutions were dried down under a steady stream of room temperature N2. The dried wells were then reconstituted with 250 pL of diluent. Reconstituted RC solutions were directly injected onto an HPLC analytical column, bypassing the extraction column. RE samples were aliquoted into an assay plate following normal sample preparation. RE samples were analyzed using the full extraction procedure (with extraction column). The analyte was tested at three concentration levels and the internal standard was tested at one. Mean extraction recovery for fenofibric acid varied from 93.2 to 111.1%, and mean extraction recovery for the Pestanal internal standard was 105.2%. 

Prepare samples (maximum of two) by grinding and weighing 5 g of each into 500-mL Erlenmeyer flasks. Add 50 mL of the HC1 solution prepared in step 1 to each. Bring each to a boil on a hot plate, and then simmer for 5 min. Cool and transfer the supernatents for each to separate 100-mL volumetric flasks. Dilute to the mark with distilled water and shake. Filter each through Whatman 1 filter paper into dry 250-mL Erlenmeyer flasks. Pipet 1 mL of each of these extracts into other clean 100-mL volumetric flasks, and dilute to the mark with water. Save the original extracts in case more dilutions are needed. 

In the preparation of adhesive patches by direct milling on a two-roll mill, the drug and the bioadhesive are homogeneously mixed with or without the aid of a solvent. The polymer/drug mixture may then be compressed to its desired thiekness and patches of appropriate size may be cut or punched out. The polymer/drug mixture prepared with a solvent may require an additional drying step by air or in an oven. 

Usually, samples are presented for analysis as liquids. Thus, solid samples must be dissolved. Analytical or ultra-high-purity grade reagents must be used for dissolution to prevent contamination at trace levels. Certain volatile metals (e.g. cadmium, lead and zinc) may be lost when dry ashing, and volatile chlorides (e.g. arsenic and chromium) lost upon wet digestion. It is particularly easy to lose mercury during sample preparation. Appropriate steps must be taken in the choice of method of dissolution, acids and conditions (e.g. whether to use reflux conditions) to prevent such losses. 

A resist pattern composition, (III), was prepared by Kubota et al. (3) that prevented a fine resist pattern from collapsing in the drying step after treatment with a developing agent. 

Lyophilization is a very common method to prepare enzymes for use in organic media, but the procedure often results in preparations having low catalytic activity. The method can cause inactivation of the enzyme both in the freezing step and in the drying step [7]. FT-IR spectroscopy has been used to study secondary structure in enzyme preparations, and lyophilization has been shown to decrease the a-helix content and increase the (i-sheet content compared to native enzyme and... 

Chlorophyll content of food systems is normally expressed based on a reference system (e.g., wet or dry weight basis). While wet weight chlorophyll content is often reported, it should be considered in the context of the preparation s total moisture, as water content may potentially vary between varieties and preparations. Therefore, these values should be accompanied by moisture content of the tissue in order to account for this innate variability. Alternatively, chlorophy 11 content expressed on a dry weight basis can easily be compared across varieties and preparations. While dry weight content is preferred, it requires a drying step (preferably freeze drying) prior to analysis,... 

The oxo derivative prepared in step (a) or the hydroxy derivative prepared in step (b) is hydrogenated in 2 N hydrochloric acid in the presence of 10% palladium on carbon at 70°C. When the uptake of hydrogen ceases, the reaction mixture is filtered and made alkaline. The product is extracted with methylene chloride which is washed with water, dried and evaporated to dryness. From the residue, which is the product as base, is made the hydrochloride of 4(5)-(2,3-dihydro-2-ethyl-lH-inden-2-yl)imidazole using dry hydrogen chloride in ethyl acetate. It has melting point 211-215°C. 

The preparation of NdP is described by Laubry [268,269]. According to this patent Nd(III) chloride hexahydrate is reacted with the respective phosphoric acid in water/acetone. After several washing and drying steps anhydrous NdP is obtained. 

Once the sections have been picked up on the glass slide and labeled correctly, they are traditionally air dried for several minutes to allow excess water to drain from the section. The prepared slides are then placed in a rack and progressed to the drying step where they are placed in an oven. The heating of the glass slides in the oven provides a twofold benefit. Excess paraffin is removed from the section while simultaneously adhering the tissue section to the slide. At the completion of this step the slides are ready for routine staining. 

---