Dry preparation

As vaccine is required to meet orders, bulk vaccine is distributed into single dose ampoules or into multidose vials as necessary. Vaccines that are filled as liquids are sealed and capped in their containers, whereas vaccines that are provided as dried preparations are fieeze-dried before sealing. 

The color was very stable in dry preparations. Sugar flowers for cake decoration maintained their color during years of storage. Foods prepared with the color include gelatin and ice cream. The color was mixed with other colorants to obtain a range of shades and hues. 

As the concentration of parathion in the propylene glycol solutions is increased, it follows that the area covered by the solution is decreased. That this is a factor in toxicity is indicated by the greater toxicity of the 10 mg. per ml. solution than the 50 mg. per ml. solution. This relationship appears to be true also of the various dry preparations, in that the 1% powder is somewhat more toxic than the 15%. The addition of water to convert the powder to paste does not appreciably influence the toxicity. In comparable concentrations the wettable powder formulation is less toxic than the propylene glycol solution. 

Most proteins are not sufficiently stable in aqueous solution to allow formulation as a sterile solution. Instead, the protein is freeze-dried and reconstituted before use. Development of a freeze-dried protein formulation often requires special attention to the details of the freezing process (potential pH shifts and ionic strength increase with freezing) as well as to potential loss of activity with drying. Formulation additives, such as sugars and polyhydroxy compounds, are often useful as cryoprotectants and lyoprotectants. Residual moisture may also be critical to the stability of the dried preparation [33],... 

Hydrazide-activated (strept)avidin may be stored as a freeze-dried preparation without loss of activity. 

Lacour, C., Laher-Lacour, F Dubon, A., Lagues, M., Mocaer, P. Freeze-drying preparation of yttrium barium copper oxide. Correlations between electrical and microstructural properties. PhysicaC (Amsterdam), 167 (3-4), p. 287-290, 1990... 

Oxidation of the Leuco-Base.—In a round-bottomed flask (capacity 1-5 1.) 11 g. of the dried preparation are dissolved in 80 c.c. of hot 2 N-hydrochloric acid and the practically colourless solution is diluted with 800 c.c. of water. To the diluted solution, which is kept cool in ice and continually shaken, a suspension of 9 g. of lead dioxide in 30 c.c. of water is added slowly in small portions. Since commercial lead dioxide often reacts badly the oxidising agent should be prepared in the laboratory by the method given below. 

Giilzow, E., Schulze, M., Wagner, N., Kaz, T., Schneider, A., and Reissner, R. New dry preparation technique for membrane electrode assemblies for PEM fuel cells. Fuel Cells Bulletin 1999 2 8-12. 

The anti-D immunological preparations used are purified from the serum or plasma of Rh-negative individuals who have been immunized against Rh-D antigen. The purified antibody preparations may be marketed as a liquid (shelf-life of 2 years when stored refrigerated) or as a freeze-dried preparation, which exhibits a shelf-life of up to 5 years. 

While the test tube dries, prepare a solution of 0.5 g of benzoin in 10 ml of methyl methacrylate. Then add 0.5 g of dibenzoyl peroxide (see Note 2). 

The drug is formulated as a freeze-dried preparation because the aqueous solution is unstable when stored for a prolonged period. However, the freeze-dried preparation does not need storage in a refrigerator. 

Separate the precipitated sodium bisulphide crystals by means of a glass filter No. 2, wash it with absolute diethyl ether, and transfer it for drying into a test tube with a ground-glass joint. Connect the test tube to a vacuum system and keep it under a vacuum (10- mmHg) at 20 G during 30 minutes. Put the dry preparation... 

Molnar, Z. Development of the parietal bone of young mice. I. Crystals of bone mineral in frozen-dried preparations. J. Ultrastructal Res. 3, 39 (1959)... 

Iley and Riley (36) have prepared graphite by cracking hydrocarbons in the presence of a fused silica support at 800° to 1300° C. Both moist and dry preparations at 1000° to 1200° C. contain from 0.5 to 1% hydrogen. They propose that these hydrogen atoms are on peripheral carbon atoms and probably inhibit crystal growth. 

Foods are supplemented with vitamin A in the form of standardized preparations of synthetic fatty acyl esters, nowadays chiefly retinyl palmitate. The preparations are available commercially as either dilutions in high-quality vegetable oils containing added vitamin E as an antioxidant or as dry, stabilized beadlets in which the vitamin A is dispersed in a solid matrix of gelatin and sucrose or gum acacia and sucrose. The oily preparations are used to supplement fat-based foods such as margarines the dry preparations are used in dried food products such as milk powder, infant formulas, and dietetic foods (24). 

Measurements are usually made on dry preparations in order to avoid the swelling of the fibres in a liquid. In this case the microscope slide is conveniently smeared with a dilute hot gelatine solution, on which the fibres are placed immediately. 

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