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Positional expression

The first requirement is the definition of a low-dimensional space of reaction coordinates that still captures the essential dynamics of the processes we consider. Motions in the perpendicular null space should have irrelevant detail and equilibrate fast, preferably on a time scale that is separated from the time scale of the essential motions. Motions in the two spaces are separated much like is done in the Born-Oppenheimer approximation. The average influence of the fast motions on the essential degrees of freedom must be taken into account this concerns (i) correlations with positions expressed in a potential of mean force, (ii) correlations with velocities expressed in frictional terms, and iit) an uncorrelated remainder that can be modeled by stochastic terms. Of course, this scheme is the general idea behind the well-known Langevin and Brownian dynamics. [Pg.20]

Note that both the numerator and denominator in the final expression are always positive expressions in the case of the denominator, we know this because is the lowest energy eigenvalue of the unperturbed system. (The denominator reduces to a difference in orbital energies.)... [Pg.271]

The rat cell line R3/1 was established from cells obtained from broncho-alveolar tissues of foetal Wistar rats at 20 days of gestation. This cell line displays a phenotype with several characteristic features of ATI cells. R3/1 cells were analysed to show a positive expression for mRNA and protein content of markers related to the ATI cell type (e.g., Tla, ICAM-1, connexin-43 and caveolin-1 and -2) [79], Whether or not this cell line can form functional tight junctions is currently under investigation in our laboratories. [Pg.268]

Murphy and colleagues (1997) compared 31 patients with childhood-onset OCD and Tourette s disorder with 21 healthy volunteers. The patient group had 100% positive expression the D8/17 marker, regardless of whether the symptoms were temporally related to... [Pg.179]

The position expression, Z(f), is obtained from a mass balance ... [Pg.780]

For other non-linear parameters, such as nuclear positions, more complicated gradient expressions are needed (see, for example, Gerratt and Mills37 for nuclear position expressions) and also sometimes more complicated constraints (for instance, constraints to prevent effective translation and rotation of the molecule as a whole in the nuclear position case), but there are no essential differences in principle. [Pg.54]

Direct immunohistochemical analysis of prostatic tissue has become very popular since the development of AR antibodies. However, a disadvantage of this technique in quantitative analysis is that the intensity of the immunohistochemical stain is dependent on the intactness of the structure of the AR. Therefore, mutations or alterations in the structure may reduce staining intensity (T5). Biochemical and immunohistochemical studies of AR content in relation to grade or stage of disease, as well as prediction of response to endocrine therapy, has been inconsistent. Nearly all primary prostate cancer specimens positively express AR protein, as determined by quantitative reverse transcriptase polymerase chain reaction (RT-PCR) analysis as well as by immunohistochemical analysis on formalin-fixed, paraffin-embedded primary prostate tissues (D12, H14). In advanced-stage prostate cancer, immunohistochemical techniques has shown that metastases in bone, the... [Pg.109]

The original method for refining an atomic position, developed for Fobs maps, was to analyze the slope and curvature of the electron density at the input position of an atom. Andrew D. Booth showed how this could be done. The slope and curvature of the electron density correspond, respectively, to the first and second derivatives of the electron density with respect to the atomic positions. Expressing the slope and curvature at the atomic center by a truncated Taylor s series,the correction to the atomic positions was derived ... [Pg.361]

This still leaves the question of whether the native receptors adopt this distribution. We took two separate approaches to this. First, we carried out the transfection with the a1B-AR-GFP fusion protein under its own promoter (20). This proved negative in vascular smooth muscle, presumably because the native expression level is low, but positive expression was found in adventitial cells. This not only showed that the transfection/promoter system was effective when the native expression level was high, but also suggested that a1B-AR expression... [Pg.156]

In order to find a discrete time and position expression for the fractional Riesz derivative in Eq. (130), we employ the Griinwald-Letnikov scheme [110-112], whence we obtain... [Pg.489]

Test sensitivity indicates the percentage of individuals in whom a test is positive for the disease in question. It is the same as the TPF. The better the sensitivity of the test, the fewer are the false negatives. Tests with a very high sensitivity can, if negative, be used to exclude the relevant disease. Test specificity refers to the percentage of individuals without the disease in question in whom a test is negative. It is the same as the TNF. The better the specificity of the test, the fewer are the false positives. Expressed somewhat differently, the false-positive rate = 1 - (specificity). Also, the falsenegative rate = 1 - (sensitivity). [Pg.626]

While it is quite likely that individuals and groups who support very liberal legalization policies also support harm-reduction groups, that does not lead to a conclusion that harm-reduction groups are attempting to legalize drugs. However, that seems to be the position expressed in the NDCS. [Pg.57]

P + F = K + 2 holds in particular if thermal, manal, and chemical equilibriums are established. There may be certain cases that need a modification, or positively expressed, the phase rule can be extended to other cases under which the conditions are not valid, e.g., surface energy. We show possible sets of solutions for phases, freedoms, and components in Table 7.1. [Pg.260]

Finally, there is the kinematic boundary condition that is just a restatement of the fact that the fluid velocity at the interface is equivalent to the total time derivative of the interface position. Expressing the total derivative using the convective terms discussed previously, we find that an interface whose position is described by a vector R obeys... [Pg.46]

The promoterless luxABCDE km operon is optimized from Gram-positive expression and is silent on pXen-5. When transposition occurs, the strength of... [Pg.236]

From Pj-, the position expressed with base coordinate 0 is given by ... [Pg.78]


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See also in sourсe #XX -- [ Pg.215 ]




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