Polyurethane biodegradation

Keywords Dried distillers grains Liquefaction Bio-polyols Polyurethane Biodegradable... 

Starch-Modified Polyurethane Biodegradable thermoplastic starch-grafted polyurethane. 

Effect of processing parameters on polyurethane biodegradation characteristics... 

Wagstaff MJD, Schmitt BJ, Caplash Y, Greenwood JE. Free flap donor site reconstruction a prospective case series using an optimised polyurethane biodegradable temporising matrix (BTM). ePlasty 2015 15 231 8. 

Whereas polyetheylene, polypropylene, and polystyrene are virtually non-biodegradable, only specially modified, not widely employed, polyamides and polyurethanes are susceptible to biodegradation [2]. Consequently, the use... 

Trimethylhexamethylene diisocyanate (TMDi) FIGURE 8.1 Diisocyanates in biodegradable polyurethanes (PUs). 

De Groot JH, de Vrijer R, Pennings AJ, Klompmaker J, Veth RPH, and Jansen HWB. Use of porous polyurethanes for meniscal reconstruchon and meniscal prosthesis. Biomaterials, 1996, 17, 163-174. Borkerhagen M, Stoh RC, Neuenschwander P, Suter UW, and Aebischer P. In vivo performance of a new biodegradable polyester urethane system used as a nerve guidance channel. Biomaterials, 1998, 19, 2155-2165. 

Goma K and Gogolewski S. Biodegradable polyurethane implants U in vitro degradadon and calcification of materials from poly (e-caprolactone)-polyethylene) diols and various chain extenders. J Biomater Res, 2002, 60, 592-606. 

Skaija GA and Woodhouse KA. In vitro degradation and erosion of degradable, segmented pol3mreth-anes containing amino acidbased chain extender. J Biomater Sci Polym Ed, 2001, 12, 851-873. Fromstein JD and Woodhouse KA. Elastomeric biodegradable polyurethane blends for soft hssue application. J Biomater Sci Polym Ed, 2002, 13, 391 06. 

Biodegradable polyurethanes have been proposed and studied before (9-72). The difference in our study is the inclusion of a phosphoester linkage instead of the commonly used polyester component. This seems to provide more flexibility as the side chain of the phosphate or phosphonate can be varied. For controlled drug delivery applications, drugs can be linked to this site to form a pendant delivery system. Moreover, for certain medical applications, fast degradation rate is obtainable by the introduction of these hydrolyzable phosphoester bonds. With the LDI based polyurethanes, drugs or other compounds of interest can also be coupled to the ester side chain of the lysine portion. 

Choi, S.H., Moon, S.H., and Gu, M.B., Biodegradation of chlorophenols using the cell-free culture broth of Phanerochaete chrysosporium immobilized in polyurethane foam, J. Chem. Technol. Biotechnol., 77, 999-1004, 2002. 

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