Polyurethane-polydimethylsiloxane copolymer

Copolymer of styrene and acrylonitrile Copolymer of styrene and butadiene Natural rubber Chlorinated polyethylene Chlorosulfonated polyethylene Polyamides Polyesters Polyurethanes Polysulfones Polyacrylates Polyacrylamides Polydimethylsiloxane Copolymer of vinylidene fluoride and hexafluoropropylene... 

Polyesters Polyurethanes Polysulfones Polyacrylates Polyacrylamides Polydimethylsiloxane Copolymer of vinylidene fluoride and hexafluoropropylene... 

Sheth JP, Aneja A, Wilkes GL et al. (2004) Influence of system variables on the morphological and dynamic mechanical behavior of polydimethylsiloxane based segmented polyurethane and polyurea copolymers a comparative perspective. Polymer 45 6919-6932. 

Several polymers were evaluated in the form of a surface coating on glass beads packed in columns to determine their ability to retain platelets when whole human blood passes over the surface. This ability was measured as the platelet retention index p, the fraction of platelets retained on the column. Lowest values of p were found for poly(ethylene oxide), polypropylene oxide), poly(tetramethylene oxide) (in the form of polyurethanes), and polydimethylsiloxane. Highest values (around 0.8) were found for cross-linked poly(vinyl alcohol) and the copolymers of ethylenediamine with diisocyanates. Intermediate values were found for polystyrene and its copolymers with methyl acrylate, for polyacrylate, and for poly(methyl methacrylate). The results are interpreted in terms of possible hydrophobic and hydrogen bonding interactions with plasma proteins. 

Test polymers for visualization studies were polyurethane (Pellethane, 2363-80A, Upjohn), filler-free polydimethylsiloxane (Sil-Med Corporation), two forms of Teflon, sintered (TFE, DuPont) and Fluorofilm (Dilectrix Corporation), and polyurethane-silicone rubber copolymer (AVCOthane 51, AVCO). Samples of 1 cm2 or, for shear studies, 5 X 20 X 0.5-cm sheets, were washed in ionic detergent solution (Alconox) at 60°C for 1 h, rinsed in deionized water, and refluxed in absolute ethanol for 1 h. Materials were dried and stored in a desiccator until use. 

Choi, T. Weksler, J. Padsalgikar, A. Runt, J., Influence of Soft Segment Composition on Phase-Separated Microstructure of Polydimethylsiloxane-Based Segmented Polyurethane Copolymers. Polymer 2009,50, 2320-2327. 

Joki-Korpela, F. Pakkanen, T. T., Incorporation of Polydimethylsiloxane into Polyurethanes and Characterization of Copolymers. Eur. Polym. J. 2011,47, 1694-1708. 

Cardiothane (Avcothane), (Trade name of Kontron Cardiovascular, USA). A copolymer of a polyether polyurethane (90%) and polydimethylsiloxane (10%) chain and activated with reactive acetoxy end-groups to enable moisture curing to be possible. 

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