Polypeptide polymeric

Polypeptide Polymerized amino acid molecules formed by enzymatically regulated stepwise polymerization in vivo between the carboxyl group of one amino add and the amino group of a second amino acid. 

Applications of click chemistry are already far too numerous to acknowledge by even offering an example fi om each area herein. Some of these areas include dendrimers, polypeptides, polymeric materials, conformationally restricted macrocycles, new ligand designs, and carbohydrates. One representative procedure is provided below. A related study describes sugar-based silica gels for use as hydrophilic interaction chromatography (HILIC) for separation of monosaccharides. ... 

I UP AC, Abbreviated nomenclature of synthetic polypeptides (polymerized amino acids) revised recommendations (1971), Biopolymers 11, 321-327 (1972). 

During the formation of the polypeptide polymeric chain, one water molecule is lost per amino acid. This is why the constituents of the proteins are called amino acid residues. There are four different types of protein structures recognized in the field. These are described in the subsequent text. 

The values of P-parameters of atoms and radicals given in the Table define their approximate equality in the directions of interatomic bonds in polypeptide, polymeric and other multiatom biological systems. 

Polyethylene (Section 6 21) A polymer of ethylene Polymer (Section 6 21) Large molecule formed by the repeti tive combination of many smaller molecules (monomers) Polymerase chain reaction (Section 28 16) A laboratory method for making multiple copies of DNA Polymerization (Section 6 21) Process by which a polymer is prepared The principal processes include free radical cationic coordination and condensation polymerization Polypeptide (Section 27 1) A polymer made up of many (more than eight to ten) amino acid residues Polypropylene (Section 6 21) A polymer of propene Polysaccharide (Sections 25 1 and 25 15) A carbohydrate that yields many monosacchande units on hydrolysis Potential energy (Section 2 18) The energy a system has ex elusive of Its kinetic energy... 

Using the same method a block copolymer of polypeptides and vinyl monomers was also prepared. As mentioned in Section II, Bamford and Mullik [22] introduced an interesting method of photoinitiation of vinyl monomers by the Mn2(CO)io or the Re2(CO)io/C2F4 system. By these methods polymeric molecule with (CO)sMn—CF2CF2—terminals is produced (see Scheme [12]). If a polymer of this kind is heated to 100°C in the presence of vinyl monomer, a block copolymer AB or ABA with Cp2- F2 linkage is produced [ ] ... 

By means of a ring-opening polymerization of the condensation type Vlasov et al. [50] synthesized polypeptide based MAIs with azo groups in the polymeric backbone. The method is based on the reaction of a hydracide derivative of AIBN and a N-carboxy anhydride. Containing one central azo group in the polymer main chain, the polymeric azo initiator was used for initiating block copolymerizations of styrene and various methacrylamides. 

Polymerization of amino acid iV-carboxyanhydrides to polypeptides exemplifies another interesting reaction which exhibits a number of unusual features. This reaction has been, and is still being, vigorously investigated by several independent groups of workers, and some recent results are particularly intriguing and deserve a detailed discussion. 

Since the late 1940s, NCA polymerizations have been the most common technique used for large scale preparation of high molecular weight polypeptides [13]. However, these materials have primarily been homopolymers, random copolymers, or graft copolymers that lack the sequence specificity and monodispersity of natural... 

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