Polychlorinated biphenyls biomarkers

Fierens, S., Mairesse, H., Heilier, J.F., De Burbure, C., Focant, J.F., Eppe, G., De Pauw, E., and Bernard, A., Dioxin/polychlorinated biphenyl body burden, diabetes and endometriosis Findings in a population-based study in Belgium, Biomarkers, 8 (6), 529-534, 2003. 

Troisi, G.M. and C.F. Mason. 1997. Cytochromes P450, P420 mixed-function oxidases as biomarkers of polychlorinated biphenyl (PCB) exposure in harbour seals (Phoca vitulina). Chemosphere 35 1933-1946. 

G. Liljegren et al., Case-control Study on Breast Cancer and Adipose Tissue Concentrations of Congener Specific Polychlorinated Biphenyls, DDE and Hexachlorobenzene, Eur. J. Cancer Prev. 7 (1998) 155-40 R. J. Helzlsouer et al., Serum Concentrations of Organochlorine Compounds and the Subsequent Development of Breast Cancer, Cancer Epidemiol. Biomarkers. Prev. 8 (1999) 525-52 J. F. Dorgan, Serum Organochlorine Pesticides and PCBs and Breast Cancer Risk Results from a Prospective Analysis, Cancer Causes and Control 10 (1999) 1-11 G. A. S. Mendonca et al., Organochlorines and Breast Cancer a Case-control Study in Brazil, Int. 

I. Romieu et al., Breast Cancer, Lactation History, and Serum Organochlorines, Am. J. Epidemiol. 152 (2000) 565-70 R. Millikan et al., Dichlorodiphenyldichloroethene, Polychlorinated Biphenyls, and Breast Cancer Among African-American and White Women in North Carolina, Cancer Epidemiol. Biomarkers. Prev. 9 (2000) 1255-40 S. D. Stellman et al., Breast Cancer Risk in Relation to Adipose Concentrations of Organochlorine Pesticides and Polychlorinated Biphenyls in Long Island, New York, Cancer Epidemiol. Biomarkers. Prev. 9 (2000) 1241-49 T. Zheng et al., Risk of Female Breast Cancer Associated with Serum Polychlorinated Biphenyls and l,l-dichloro-2,2 -bis(p-chlorophenyl)ethylene, Cancer Epidemiol. Bio-... 

F. Laden et al., Plasma Organochlorine Levels and the Risk of Breast Cancer An Extended Follow-up in the Nurses Health Study, Int. J. Cancer 91 (2001) 568-74 K. J. Aronson et al., Breast Adipose Tissue Concentrations of Polychlorinated Biphenyls and Other Organochlorines and Breast Cancer Risk, Cancer Epidemiol. Biomarkers. Prev. 9 (2000) 55-65. 

For chemicals with half-lives of months or years—such as dioxins, polychlorinated biphenyls (PCBs), polybrominated biphenyl ethers, and first-generation halogenated insecticides—biomarkers can detect exposures months or even years after they have occurred. Such lipophilic chemicals are usually measured in blood, and the principal exposure source is usually diet. After ingestion, they are readily absorbed into the blood supply blood concentration then decreases rapidly as the blood supply equilibrates with... 

Aronson, K.J., Wilier, A.B., Woolcott, C.G., Sterns, E.E., McCready, D.R., Lickey, L.A., Fish, E.B., Hiraki, G.Y., Holloway, C., Ross, T., Hanna, W.M., SenGupta, S.K., Weber, J.P., 2000. Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk. Cancer Epidemiol. Biomark. Prev. 9,... 

Griffin, P., Jones, K., and Cocker, J., Biological monitoring of polychlorinated biphenyls in plasma a comparison of enzyme-linked immunosorbent assay and gas chromatography detection methods, Biomarkers, 2, 193-195, 1997. 

Biomarkers Used to Identify or Quantify Exposure to Polychlorinated Biphenyls... 

Aronson KJ, Miller AB, Woolcott CG, et al. 2000. Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk. Cancer Epidemiol Biomarkers Prev 9 55-63. 

Moysich KB, Shields PG, Freudenheim JL, et al. 1999. Polychlorinated biphenyls, cytochrome P4501 Al polymorphism, and postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev 8 41-44. 

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