Poly matrix assisted laser desorption

Arnold, R. J. Reilly, J. P. Observation of tetrahydrofolyl-poly-glutamic acid in bacteria cells by matrix assisted laser desorption/ionization mass spectrometry. Anal. Biochem. 2000,281,45-54. 

Figure 15.1. MALDI spectrum of a polycarbonate sample along with peak assignment. In the inset, an expansion of the spectral region from 3.0 up to 3.7 kDa is shown. (Reproduced from Puglisi, C. et al., 1999. Analysis of Poly(bisphenol A Carbonate) by Size Exclusion Chromatography/Matrix-Assisted Laser Desorption/lonization. I. End Group and Molar Mass Determination. Rapid Communications in Mass Spectrometry, 13 2260-2267. With permission of John Wiley Sons, Inc.)...

Matrix-Assisted Laser Desorption/lonization Time-of-liight Mass Spectrometry (MALDI-TOF MS, PerSeptive Biosystems Voyager-DE STR) was used to characterize the molecular weight distribution and the number average molecular weight (M ) of the poly(methacrylic acid) (PMAA) degradation products as described elsewhere [25]. 

The use of diisoprop anolamine in the synthesis of the hyperbranched poly-esteramide resins has led to defined molecules according to the predicted structures (Fig. 7) as confirmed by MALDI-TOF (Matrix Assisted Laser Desorption Ionization - Time Of Flight) and ESI (Electro Spray Ionization) mass spectra... 

Abbreviations AOD, Acousto-optical deflection BCB, bisbenzyocyclobutadiene CCD, indirect contact conductivity detection CL, chemiluminescence ECD, electron capture detector FCS, fluorescence correlation spectroscopy FRET, fluorescence resonance energy transfer ICCD, integrated contact conductivity detection GMR, giant magnetoresistive LED-CFD, light emitting diode confocal fluorescence detector LIF, laser-induced fluorescence LOD, limit of detection MALDI, matrix-assisted laser desorption ionization PDMS, poly(dimethylsiloxane) PMMA, poly(methylmetha-crylate) SPR, surface plasmon resonance SVD, sinusoidal voltammetric detection TLS, thermal lens spectroscopy. 

There has been considerable debate over the reason why TEMPO does not work well for acrylates. CNRS researchers utilized NMR and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) techniques to look at the terminal end-groups on poly(n-butyl acrylate) produced using TEMPO mediation [19]. They found that most of the chains were terminated by co-unsaturation resulting from either elimination or O-H TEMP from the chain-end or disproportionation between TEMPO and the polyradical (Scheme 8.7). 

Laser desorption/ionization (LDI) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MSs have become useful tools for the characterization of various conducting polymers. For instance, analysis of poly[2,5-di(thien-2-ylidene)-l,3,4,6-tetrathiapentalene] 56 (DT-TTP) showed ions above mlz = 500 corresponding to oligomers of DT-TTP with up to five monomer units <2000JMP550>. 

For natural poly-APS alkaloids (77), matrix assisted laser desorption ionization-time-of-flight (MALDI-TOF) spectrometric analysis showed that the compounds comprised a mixture of two polymers with molecular weights centred at around 5520 Da and 18900 Da and with a low degree of polydispersity [34]. 

Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry of Anthocyanin-poly-flavan-3-ol Oligomers in Cranberry Fruit Vaccinium macrocarpon. Ait.) and Spray-Dried Cranberry Juice... 

Muller, M., Schiller, J., Petkovic, M., Oehrl, W., Heinze, R., Wetzker, R., Arnold, K. and Arnhold, J., Limits for the detection of (poly-)phosphoinositides by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDITOF MS), Chem Phys Lipids, 110 (2001) 151-164. 

Bullock J, ChowdhuryS, Johnston D (1996). Characterization of poly (ethylene glycol)-modified superoxide dismutase Comparison of capillary electrophoresis and matrix-assisted laser desorption/ionization mass spectrometry. Analyt. Chem. 68 3258-3264. 

In poly(ether sulfone)s that are prepared by polycondensation of silyl-ated 4-terf-butylcatechol and 4,4 -difluorodiphenyl sulfone, macrocyclic polymers were obtained to some extent. The cyclic polymers were detected by means of matrix-assisted laser desorption ionization time of flight (MALDI-TOF) mass spectrometry. 

MALDI Matrix-assisted laser desorption/ionization MAPP Maleated poly(propylene)... 

Jackson, A. T., Yates, H. T., Scrivens, J. H., Green, M. R., and Bateman, R. H., Matrix-assisted laser desorption/ionization-collision induced dissociation of poly(styrene), /, Am. Soc. Mass Spectrom., 9, 269, 1998. 

Pastor, S. J., Wood, S. H., and Wilkins, C. L., "Poly(ethylene glycol) Limits of Detection Using Internal Matrix-assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometry," /. Mass Spectrom., 33, 473—479,1998. 

Hoberg, A.-M., Haddleton, D. M., Derrick, P. J., Jackson, A. T., and Scrivens, J. H., The Effect of Counter Ions in Matrix-assisted Laser Desorption/Ionization of Poly(methyl methacrylate), Eur. Mass. Spectrom., 4, 435,1998. 

Haddleton, D. M., Waterson, C., and Derrick, P. Comment A Simple, Low-cost, Air-spray Method for Improved Sample Preparation for Matrix-assisted Laser Desorption/Ionization Mass Spectrometry of Derivatised Poly(ethylene glycol), Eur. Mass. Specirom., 4, 203,1998. 

Danis, P. O. and Karr, D. E., Analysis of Poly(styrenesulfonic acid) by Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry, Macromolecules, 28, 8548, 1995. 

Montaudo, G., Montaudo, M. S., Puglisi, C., and Samperi, P., Characterization of Polymers by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Molecular Weight Estimates in Samples of Var5ring Poly-dispersity Rapid Comm. Mass Spectrom., 9, 453, 1995. 

Lloyd, P. M., Suddaby, K. G., Varney J. E., Scrivener, E., Derrick, P. J., and Eladdleton, D. M., A Gomparison Between Matrix-assisted Laser Desorption/ Ionization Time-of-flight Mass Spectrometry and Size Exclusion Chromatography in the Mass Characterisation of Synthetic Polymers with Narrow Molecular-mass Distributions Poly(mefhyl methacrylate) and Poly(styrene), Eur. Mass Spectrom., 1, 293, 1995. 

Pasch, H. and Gores, R, Matrix-assisted Laser Desorption/Ionization Mass Spectrometry of Synthetic Polymers 2. Analysis of Poly(methyl methacrylate). Polymer, 36, 1999, 1995. 

Williams, J. B., Gusev, A. L, and Hercules, D. M., Use of Liquid Matrices for Matrix-Assisted Laser Desorption Ionization of Polyglycols and Poly(dimeth-ylsiloxanes). Macromolecules, 29, 8144, 1996. 

Weidner, St., Kuhn, G., and Just, U., Characterization of Oligomers in Poly(eth-ylene terephthalate) by Matrix-assisted Laser Desorption/Ionisation Mass Spectrometry, Rapid Comm. Mass. Spectrom., 9, 697,1995. 

Linnemayr, K., Vana, P, and AUmaier, G., lime-delayed Extraction Matrix-assisted Laser Desorption Ionization lime-of-flight Mass Spectrometry of Poly-acrylnitrile and Other S3mthetic Polymers with the Matrix 4-Hydroxyben-zylidene Malononitrile, Rapid Comm. Mass Spectrom., 12,1344, 1998. 

Larsen, S. B., Simonsick, W. J. Jr., and McEwen, C. N., Fundamentals of the Applications of Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry to Low Mass Poly(methylmethacrylate) Polymers, /, Am. Soc, Mass Spectrom., 7, 287, 1996. 

Sakurada, N., Fukuo, T., Arakawa, R., Ute, K., and Hatada, K., Characterization of Poly(methyl methacrylate) by Matrix-assisted Laser Desorption Ionization Mass Spectrometry. A Comparison with Supercritical Fluid Chromatography and Gel Permeation Chromatography, Rapid Comm, Mass Spectrom., 12, 1895, 1998. 

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