Pityrosporum ovale

Ketoconazole, 1% shampoo, apply every 3-4 days Nizoral A-D Synthetic azole antifungal agent with activity versus Pityrosporum ovale, a fungus that may cause seborrhea and dandruff. Massage over entire scalp for 3 minutes. Rinse thoroughly and repeat application. 

Leino, M., Reijula, K., Makinen-Kiljunen, S., Haahtela, T., Makela, M.J., and Alenius, H. 2006. Cladosporium herbarum and Pityrosporum ovale allergen extracts share crossreacting glycoproteins. Int Arch Allergy Immunol 140(1) 30-35. 

Lithium succinate ointment also has proved to be useful in the treatment of seborrhoeic dermatitis, having an effect both on the lipid metabolism of the normal skin fungus, Pityrosporum ovale, which proliferates excessively in this condition, and on the general inflammatory effect, which is the normal response to such fungal attack (212, 213). Further extensions of the antiviral and topical uses are expected and the area is rapidly developing. 

Moniliella suaveolens, Trichoderma harzianum, Pityrosporum ovale, and Ceratocytis moniliformis form decalactones (problems with phenolic components)... 

It is now generally recognised to be associated with the presence of high levels of the yeast Pityrosporum ovale, although it has not been determined conclusively whether the yeast is the cause of the condition or merely encouraged by the abundance of nutrients from shed skin cells. 

Seborrheic dermatitis, resulting from an excess production of sebum and overgrowth of the commensal yeast Pityrosporum ovale,improves rapidly but only temporarily after the application of TCA peels. Follow-up treatment after the peels consists simply of applying vinegar every morning before showering (for the antiseptic qualities of the acetic acid) and the use of antimycotic creams. In some cases, the reaction of the yeast and metabolites causes eczema, which can be treated with topical corticosteroids. It should be noted that Easy Phytic ... 

Gardnerella vaginalis Staphylococcus aureus Pityrosporum ovale ... 

Benham, R. W. Cultural characteristics of Pityrosporum ovale — a lipo-... 

For example, the yeast Pityrosporum ovale, the major scalp resident, is able to metabolize lipid substrates to 4-hydroxy-aclds which readily undergo ring closure to the volatile and odorous Y lactones. The technique of headspace concentration on Tenax followed by gas chromatographic/mass spectrometric analysis has been used to profile all the volatiles produced by Pityrosporum (Figure 1). These compounds Include isopentanol, benzyl... 

Figure 1. Odor profile of Pityrosporum ovale C501...

Acne itself is a disorder of the pilosebaceous follicles and these follicles as well as the adjacent skin surface are well populated with micro-organisms. Three micro-organisms have been implicated in 2icnc - Propionibacterium acnes, Staphylococci spp. and Pityrosporum ovale-With the former being the most important. However, micrococci, sarcina and yeasts are also present and a change in their population may predispose the patient to acne (Holland and Cunliffe, 1979). 

Activity as fungicide (IOO5), against Pityrosporum ovale (2286). 

Kieffer M, Bergbrant IM, Faergemann J, Jemec GB, Ottevanger V, Stahl Skov P, Svejgaard E. Immune reactions to Pityrosporum ovale in adult patients with atopic and seborrheic dermatitis. J Am Acad Dermatol 1990 22(5 Pt l) 739-742. 

Rokugo M, Tagami H, Usuba Y, Tomita Y. Contact sensitivity to Pityrosporum ovale in patients with atopic dermatitis. Arch Dermatol 1990 126(5) 627-632. 

It is clear that oleic acid enters into the growth requirements of a sufficiently wide variety of micro-organisms to make it not unlikely that it w ill be found of general importance. The variation of concentration required, from about 100 mg./lO ml. medium with the fungus Pityrosporum ovale to 0.01 mg./ml. for Cl. tetani suggests that it may be used for quite different functions in these organisms. This does not exclude also some common functions. 

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