Pit viper venom

Ancrod is an enzyme obtained from Malayan pit viper venom. It produces... 

Waglerin-1 (= 22 amino acid peptide)] (polypeptide) Wagler s pit viper venom GABAA-R chloride current block (3)... 

Hemolytic anemia may be induced in domestic animals by copper, zinc, phenothi-azine, onions, TIcernibrum (red maple), Srassica species (rape e and forage), kale], saponin-containing plants, and rattlesnake or other pit viper venoms. 

A. Thrombin-Like Enzymes. Because the high coagulant activity of Malayan pit viper venom, the thrombin-like enzyme arvin (ancrod) was isolated from this venom. Arvin has been extensively studied because it is used as a therapeutic drug for diseases such as thrombosis or myocardial infarction, which involve fibrinogen. 

Fibrinolytic effecting protease enzyme with glycoprotein structure relative mol mass ca. 30000. Isolation from the poison secretion (venom) of Agkistrodon rhodostoma (malayan pit viper) with chromatographic purification. 

Zagreb antivenin European viper venom antisera Polyvalent Crotalidae antivenin Micrurus fulvius antivenin Australian polyvalent antivenins Adder bites One or more species of viper Any one of four species of pit viper (including Western diamond back and South American rattlesnake Eastern coral snake Micrurus fulvius) Any one or combination of black snake, brown snake, death adder, taipan and tiger snake... 

Snake bite (pit vipers) Antivenin (Crotalidae) polyvalent, equine The entire dose should be given within 4 hours after the bite by the IV or IM route (1 vial = 10 mL) Minimal envenomation 2-4 vials Moderate envenomation 5-9 vials Severe envenomation 10-15 vials Additional doses may be required. Neutralizes the venom of rattlesnakes, copperheads, cottonmouths, water moccasins, and tropical and Asiatic crotalids. Serum sickness occurs in almost all patients who receive > 7 vials. 

Molossin is a 15 amino acid moiety derived from the snake venom of the American pit viper Crotuluis molossus molossus, encompassing the RGDNP motif which has an affinity for and integrins. A 31 amino acid peptide containing molossin for cellular targeting and an oligolysine of 16 residues (K16) as... 

Venom of the Malayan pit-viper Agkistrodon rhodostoma Triethylaminoethyl cellulose powder (Serva) tris(Hydroxymethyl)aminomethane... 

The discovery of teprotide led to a search for new, specific, orally active ACE inhibitors. Ondetti et al. (172) proposed a hypothetical model of the active site of ACE, based on analogy with pancreatic carboxypeptidase A, and used it to predict and design compounds that would occupy the carboxy-terminal binding site of the enzyme. Carboxyalkanoyland mer-captoalkanoyl derivatives of proline were found to act as potent, specific inhibitors of ACE and 2-D-methyl-3-mercaptopropanoyl-L-proline (131) (captopril) was developed and launched in 1981 as an orally active treatment for patients with severe or advanced hypertension. Captopril, modeled on the biologically active peptides found in the venom of the pit viper, made an important contribution to the understanding of hypertension and paved the... 

Agistrodon Piscivorus Most poisous snakes in the United States and tropical regions are pit vipers. Pit vipers are a group of venomous snakes that have deep depressions on each side of the face between the nostril and the eye. These are associated with a membrane that is incredibly sensitive to changes in temperature and serves to detect the presence of infra-red heat. Equipped with the most efficient natural heat receptors in the animal world, these pits allow the snake to sense the heat difference between a small animal and the cooler rocks, plants and other objects in the area. When a warm-blooded animal ventures closer than 20", the snake can detect the prey entirely... 

Anticoagulant thrombin-like enzyme found in venom of Malayan pit viper, Agkistrodon rhodostoma. 

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