Phenobarbitone sodium

Jalsenjak, I., Nicolaidou, C.F. and Nixon, J.R. (1976) The in vitro dissolution of phenobarbitone sodium from ethylcellulose microcapsules. Journal of Pharmacy and Pharmacology, 28, 912-914. 

Male albino rats within the weight range 150-250 g are treated with phenobarbitone sodium 16mgml 1, 2.5mlkg 1 in sterile saline, and /i-naphthoflavonc 20 mg ml-1 in com oil. A fine suspension of the latter is achieved by sonicating for lh. These solutions are dosed by intraperitoneal injection on days 1, 2, and 3. 

Phenobarbitone sodium is normally administered between 0.5 and 2h prior to /Tnaphthoflavonc. 

Procedure Weigh accurately 0.5 g phenobarbitone sodium and dissolve in 15 ml of DW. Add to it 5 ml of 2 M hydrochloric acid and extract with 50 ml of ether and then with successive 25 ml quantities of ether until complete extraction is affected. Wash the combined extracts with two 5 ml quantities of DW and wash the combined aqueous extracts with 10 ml quantities of ether. Add the ether to the main ethereal extract, evaporate to low bulk, add 2 ml of absolute ethanol, evaporate to dryness and dry the residue to constant weight at 105°C. Each g of residue is equivalent to C12HnN2Na03. 

Methadone Hydrochloride Visual incompatibilities of methadone hydrochloride were observed with solutions of aminophylline, ammonium chloride, amylo-barbitone sodium, chlorothiazide sodium, heparin sodium, nitrofurantoin sodium, novobiocin, pentobarbitone sodium, phenobarbitone sodium, phenytoin sodium, quinalbarbitone sodium, sodium bicarbonate, sodium iodide, sulfadiazine sodium, sulfafurazole diethanolamine, or thiopentone sodium. 

Phenobarbitone Sodium Phenobarbitone sodium decomposes in aqueous solutions. Barbiturate poisoning may be treated with stomach wash and administration of activated charcoal. Monitoring respiratory, cardiovascular, and renal functions, hemodialysis, charcoal administration, forced diuresis, symptomatic and supportive therapy, and peritoneal dialysis may be performed. 

Phenmetrazine chlorotheophyllinate, 882 Phenmetrazine hydrochloride, 882 Phenmetrazine theoclate, 882 Phenobarbital, 883 Phenobarbital sodium, 883 Phenobm bitone, 25, 883 (metabolite), 771,923 therapeutic drug monitoring, 109 Phenobarbitone sodium, 883 Phenobarbitone, soluble, 883 Phenoctide, 830 Phenododecinium bromide, 570 Phenol, 884 (metabolite), 380 Phenolphthalein, 885 Phenomorphan, xvii Phenomycilline, 887 Phenoperidine, 885 Phenoperidine hydrochloride, 886 Phenopromini sulphas, 349 Phenopropazine, 599 Phenothiazine, 886... 

SYNS 5-ETHYL-5-PHENYLBARBITUR1C ACID SODIUM 5-ETHYX-5-PHENYLBARBITURIC ACID SODIUM SALT 5-ETHYL-5-PHENYL-2,4,6-(1 H,3H,5H)PYRIMIDINETRIONE MONOSODIUM SALT GARDENAL SODIUM LUMINAL SODIUM PBS PHENEMALUM PHENOBAL SODIUM PHENOBARBITAL ELIXIR PHENOBARBITAL Na D PHENOBARBITAL SODIUM PHENOBARBITAL SODIUM SALT PHENOBARBITONE SODIUM PHENOBARBITONE SODIUM SALT PHENYLETHYL-BARBITURIC ACID, SODIUM SALT SODIUM-5-ETHYL-5-PHENYLBARBITURATE SODIUM PHENOBARBITAL SODIUM PHENOBARBITONE SODIUM PHENYLETHYLBARBITURATE SODIUM PHENYLETHYLMALONYLUREA SOL PHENOBARBITAL SOL PHENOBARBITONE SOLUBLE PHENOBARBITAL SOLUBLE PHENOBARBITONE... 

Nagavi BG, Mithal BM, Marwadi PR, Dutta R. Solid phase interaction of phenobarbitone sodium with some adjuvants. Indian J Pharm Set 1983 45(Jul-Aug) 175-177. 

Capsules of Amylobarbitone Sodium, J5.P., Tablets of Amylobar-bitone Sodium, P.P. Tablets of Barbitone Sodium, P.P., Tablets of Pentobarbitone Sodium, P.P., and Tablets of Phenobarbitone Sodium, P.P. The tablets are liable to absorb carbon dioxide rapidly on exposure and liberate a considerable proportion of free barbiturate, extractable with ether from the powdered material. 

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