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Pharmaceuticals, synthesis

A catalyst is a substance whose presence increases the rate of a chemical reaction. The exercise of using catalysts is called catalysis. Today the vast majority of all commercially important chemical reactions involve catalysts, especially in the fields of energy production, petrochemicals manufacture, pharmaceuticals synthesis, and environmental protection. [Pg.223]

Bench-scale experimentation, in large-scale pharmaceutical synthesis,... [Pg.91]

Milling equipment, pilot plant, 18 732 Milling techniques, in large-scale pharmaceutical synthesis, 18 729 Millipedes, alkaloids in, 2 75 Millisecond catalytic cracking (MSCC) process, 11 685... [Pg.588]

Pharmaceuticals, 18 682-721. See also Food and Drug Administration (FDA) Large-scale pharmaceutical synthesis Pharmaceutical products accelerated development/review for, 18 697... [Pg.690]

Process research, in fine chemical research and development, 11 426 Process reviews, 10 163 Process risk analysis, in large-scale pharmaceutical synthesis, 16 726 Process safety, 20 731-732 Process safety management, 21 826 standards for, 21 592 Process Safety Management (PSM) of Highly Hazardous Chemicals standard, 21 829... [Pg.762]

Hsu et have cloned two enzymes from Deimcoccus radiodurans for overexpression in E. coli in order to carry out a dynamic kinetic resolution to obtain L-homophenylalanine, frequently required for pharmaceutical synthesis. The starting material is the racemic mixture of A acetylated homophenylalanine, and the two enzymes are an amino acid A -acylase, which specifically removes the acetyl group from the L-enantiomer, and a racemase, which interconverts the D- and L-forms of the A acyl amino acids. The resolution was carried out successfully using whole-cell biocatalysts, with the two enzymes either expressed in separate E. coli strains or coexpressed in the same cells. [Pg.85]

In the pharmaceutical synthesis industry, piperidine is used in some drugs such as budipine (antiparkinsonian drug), raloxifene (used in the prevention of osteoporosis), minoxidil (an oral drug to treat high blood pressure). Minoxidil has the interesting side effect of hair growth and reverses hair loss. A two percent minoxidil solution can be used to treat this condition. [Pg.117]

Five- and six-membered azacyclic rings are the basic building blocks of pharmaceutical synthesis. Several powerful methods for the construction of such rings that recently have been developed are highlighted here. [Pg.74]

While N-heterocycles have dominated pharmaceutical synthesis from its inception, the increasing facility with which complex cyclic ethers can be assembled suggests that such cyclic ethers could also be suitable pharmaceutical platforms. [Pg.102]

The major uses of mixed xylene are in aviation gasoline and protective coatings, and as a solvent for alkyd resins, lacquers, enamels and rubber cements. wetrr-Xylene is used as a solvent, as an intermediate for dyes and organic synthesis, especially isophthalic acid and insecticides, and in aviation fuel or// o-xylene is used in manufacture of phthalic anhydride, vitamin and pharmaceutical synthesis, dyes, insecticides, motor fuels para-xylene is used in synthesis of terephthalic acid for polyester resins and fibres, vitamin and pharmaceutical syntheses, and insecticides (Lewis, 1993). [Pg.1190]

CyanessigsUure-amid or Malonsaure-amid-nitril in Ger), NC.CH2CONH2 mw 84.08, N 33-32% wh crysts, mp 120°, bp dec sol in w ale prepd by ammon(jlysis of cyano acetic ester or by dehydration of ammonium cyano-acetate. The compd is highly toxic. It is used in plastics and as an intermediate in general in org pharmaceutical synthesis Refs l)Beil 2, 589, (256) [534] 1632 2)Kay-Fries Chemicals, Inc (NY) Tech Data Bull (preliminary) "Cyanoacetamide (Feb 1951) 3)Sax (1957), 522 4)Cond Chem Diet (1961), 322... [Pg.366]

Understand the role of green chemistry in pharmaceutical synthesis and be able to analyze a synthesis using various green metrics... [Pg.321]

Know the role of regulatory agencies in the oversight of pharmaceutical synthesis... [Pg.321]

At least one of the 12 principles—number 2, design safe products—is a must for pharmaceutical synthesis. Indeed, pharmaceutical products are regulated and tested for safety. Principle number 7, maximize atom economy, refers to a metric against which the greenness of a process may be evaluated. Green metrics are covered in the next section. [Pg.342]


See other pages where Pharmaceuticals, synthesis is mentioned: [Pg.305]    [Pg.71]    [Pg.259]    [Pg.512]    [Pg.118]    [Pg.128]    [Pg.411]    [Pg.510]    [Pg.650]    [Pg.709]    [Pg.788]    [Pg.788]    [Pg.788]    [Pg.866]    [Pg.869]    [Pg.917]    [Pg.72]    [Pg.15]    [Pg.174]    [Pg.33]    [Pg.259]    [Pg.748]    [Pg.794]    [Pg.1169]    [Pg.321]    [Pg.322]    [Pg.324]    [Pg.326]    [Pg.328]    [Pg.330]    [Pg.332]    [Pg.334]    [Pg.336]    [Pg.338]    [Pg.340]    [Pg.342]    [Pg.344]   
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See also in sourсe #XX -- [ Pg.185 ]

See also in sourсe #XX -- [ Pg.693 ]

See also in sourсe #XX -- [ Pg.215 , Pg.299 , Pg.333 , Pg.355 ]




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Active pharmaceutical ingredients synthesis

Active pharmaceutical synthesis

Application in the Synthesis of Pharmaceutically Active Ingredients

Application in the Synthesis of Pharmaceuticals

Aspects in Pharmaceutical Synthesis

Asymmetric epoxidation pharmaceutical products synthesis

Biological Synthesis of Pharmaceuticals

Chiral pharmaceuticals, synthesis

Diols pharmaceutical syntheses

Drug synthesis pharmaceutical applications

Examples of Pharmaceutical Co-crystal Synthesis and Screening Using Mechanochemistry

Fine chemical and pharmaceutical synthesis

Mechanochemical Synthesis of Pharmaceutical Salts

Modification of Gums Synthesis Techniques and Pharmaceutical Benefits

Pharmaceutical products process synthesis

Pharmaceutical research company synthesis

Pharmaceuticals chemical synthesis

Pharmaceuticals, organic synthesis

Proteins, chemical synthesis pharmaceuticals

Synthesis of Natural Products and Pharmaceuticals via Catalytic C-H Functionalization

Synthesis of Pharmaceutical Compounds

Synthesis of Pharmaceutically Relevant Chiral Tetrahydrofurans

Synthesis of pharmaceuticals

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