Persulfides

Chemical Designations - Synonyms Phosphoric sulfide Phosphorus persulfide Thiophosphoric anhydride Chemical Formula PjSj-P Sm. 

Hydro-peroxyd, n. hydrogen peroxide, -per-sulfid, n. hydrogen persulfide, hydro-phil, n. hydrophile, hydrophil(ie). -phob, a. hydrophobe, hydrophobie. 

Poly-morphie, /. polymorphism, polymorphy, -nom, n. polynomial, -saure, f. poly add. -schwefelwasserstoff, m. hydrogen persulfide (either H2S2 or HaSa). -sUiciumsaure,/. polysilicic acid, -styrol, n. polystyrene, -thion s ure, /. polythionic acid, -zimtsaure, /. polycinnamic acid, polyzyklisch, a. polycyclic. 

Inhibition of monoamine oxidase has been proposed as a possible mechanism underlying the hydrogen sulfide-mediated disruption of neurotransmission in brain stem nuclei controlling respiration (Warenycia et al. 1989a). Administration of sodium hydrosulfide, an alkali salt of hydrogen sulfide, has been shown to increase brain catecholamine and serotonin levels in rats. It has also been suggested that persulfide formation resulting from sulfide interaction with tissue cystine and cystinyl peptides may underlie some... 

The PHSS method of real-time H2S measurement allows for investigating the potentially complex H2S kinetic responses of organs, tissues, cells, and mitochondria as levels of 02 and NO as well as metabolic state are adjusted within physiological limits. Kinetic changes in H2S concentration continuously reported by the PHSS, which are not seen with other H2S measurement techniques, suggest potentially complex interactions of H2S production and consumption mechanisms. H2S may likely exist as a cellular pool of free and labile persulfides able to rapidly respond to redox challenges with production and consumption pathways that operate to maintain the pool. This possible scenario reinforces the need for the PHSS as a valuable tool to provide a continual report of H2S throughout the course of an experimental treatment or to accurately determine H2S levels in situ. 

Another enzyme, cysteine desulfurase, converts L-cysteine to L-alanine and a sulfane sulfur - a chain of divalent sulfur atoms. A protein-bound cysteine persulfide is formed on a conserved cysteine residue. Such enzymes have important roles in the biosynthesis of Fe-S clusters and sulfur-containing cofactors.9... 

The metabolism of cyanide has been studied in animals. The proposed metabolic pathways shown in Figure 2-3 are (1) the major pathway, conversion to thiocyanate by either rhodanese or 3-mercapto-pyruvate sulfur transferase (2) conversion to 2-aminothiazoline-4-carboxylic acid (Wood and Cooley 1956) (3) incorporation into a 1-carbon metabolic pool (Boxer and Richards 1952) or (4) combining with hydroxocobalamin to form cyanocobalamin (vitamin B12) (Ansell and Lewis 1970). Thiocyanate has been shown to account for 60-80% of an administered cyanide dose (Blakley and Coop 1949 Wood and Cooley 1956) while 2-aminothiazoline-4-carboxylic acid accounts for about 15% of the dose (Wood and Cooley 1956). The conversion of cyanide to thiocyanate was first demonstrated in 1894. Conversion of cyanide to thiocyanate is enhanced when cyanide poisoning is treated by intravenous administration of a sulfur donor (Smith 1996 Way 1984). The sulfur donor must have a sulfane sulfur, a sulfur bonded to another sulfur (e.g., sodium thiosulfate). During conversion by rhodanese, a sulfur atom is transferred from the donor to the enzyme, forming a persulfide intermediate. The persulfide sulfur is then transferred... 

Recently, however, polyferrocenes have been found which display a different electrochemical behaviour. For example, Figure 27 shows the cyclic voltammetric response of poly(ter/-butylferrocenyl)persulfide. 

Figure 27 Cyclic voltammogram recorded in a CH2CI2 solution of polyf tert-butyl-ferrocenyl) persulfide...

The appearance of two separate oxidation processes in these polymers is attributed to the existence of electronic communication between the ferrocene units, so that the first oxidation is centred on alternating ferrocene sites, whereas the second oxidation is centred on the remaining sites. For example, for polyferrocenyl-persulfide, the electron removal path reported in Scheme 3 has been proposed (the oxidation state of the iron atoms is represented).42... 

Clausen T, Kaiser JT, Steegborn C, et al. 2000. Crystal structure of the cystine C-S lyase from Synechocystis stalibization of cysteine persulfide for FeS cluster biosynthesis. Proc Natl Acad Sci USA 97 3856-61. 

Silver M, Kelly DP. 1976b. Thin layer chromatography of oxidised and reduced lipoate and lipoamide and their persulfides. J Chromatog 123 479-81. 

Synonyms Phosphorus sulfide phosphorus persulfide phosphorus sulfide, thiophosphoric anhydride... 

Reaction of this with Sg molecules gives a persulfidic complex (X benzothiazole). 

Phosphorus Bromide Phosphorus Oxychloride Phosphorus Pentasulfide Phosphorus Persulfide Phosphorus Tribiomide Phosphorus Trichloride... 

PHOSPHORUS PENTASULFIDE Phosphoric sulfide, Phosphorus persulfide, Thiophosplioric anhydride Flammable Solid, II 3 2 W... 

A crystal structure determination of [pyH]4[Mo203(S04)(NCS)6] has shown the two molybdenum atoms to be bridged by one oxo and the sulfato ligand. The terminal oxygens are syn and each molybdenum has a distorted octahedral geometry.415 Persulfide bridges have been identified in several dimeric Mov complexes. In each molybdenum is... 

Both noselite and ultramarine contain AI, i,Om formula units. What is the charge on this unit tn addition, noselite contains a sulfate ion and ultrumunnc has a persulfide ion. How many sodium ions are present in each overall empirical formula ... 

Thus any simple attempt to let thiols coordinate to Cu(ll) wdl result in persulfides and Cu(l). 

A peculiarity of several acyl-CoA dehydrogenases is a bright green color with an absorption maximum at 710 nm. This was found to result from tightly bound coenzyme A persulfide (CoA-S-S ).244-245... 

Coenzyme A persulfide 790 Coenzyme A transferases 662 Coenzyme 788 Coenzyme M 813s, 814, 815 Coenzyme M reductase mechanism of 881 scheme 880... 

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