Personalized medicine delivery

Keywords Drug delivery systems Targeted drug delivery Nanoparticles Nanobiotechnology Personalized medicine Routes of drug administration Drug delivery devices Controlled release Protein/peptide delivery Drug formulations... 

The remaining elements of this chapter do not address adherence per se but the types of dose form that may be valuable in personalized medicine, from the very simple fast-dissolving tablets and buccal films to more complex electronically driven microdevices. Some delivery systems can take the patient side of variability out of the equation. It is suggested that intelligent inhalers (13) reduce the dependence of inhaled dose of the patient s inspiratory flow, for example. 

Volume 2 addresses the applications and approaches in advanced drug delivery systems, including transdermal, pulmonary, and ocular routes. In addition, this text discusses the impact of the shift to personalized medicines in the fields of pharmaceutical biotechnology, pharmacogenomics, and nanotechnology. 

Overall, by using the principles of pharmacogenomics, personalized medicine, and pharmacotyping in patient care, and by monitoring their impact on current drug development and delivery, a major benefit is expected upon co-evaluation of... 

Vizirianakis IS (2004). Challenges in current drug delivery from the potential application of pharmacogenomics and personalized medicine in clinical practice. Curr. Drug Deliv. 1 73-80. 

The next step in this development is using dendritic scaffolds for the construction of theranostic nanodevices, that is, systems that combine therapeutic delivery with diagnostic imaging. Such systems are of great interest for more individualized therapy (personalized medicine) in which targeting ligands are also incorporated. Of course, such systems are indeed very complicated and will require much of the synthetic design to be reproducible. Very few examples have so far... 

Although it may often be permissible for health reasons to classify patients by race or ethnicity, some uses of race in the health area would not be acceptable, for example, unfounded negative stereotypes about the need of African Americans for pain relief or other medical procedures. (Institute of Medicine, 2002). The impermissibility of some uses of race, however, does not negate their permissibility in other areas. As we will see, the impermissible uses are more likely to involve health delivery issues, are less closely tied to the health effects of biological or genotypic differences, and are only indirectly connected with minority health care. In addition, another person is often excluded or hurt by the racial classification at issue. 

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