Dendritic scaffolding

Remarkable concentration of the photon energy absorbed by aromatic dendritic scaffold toward the focal point (herein called antenna effects ) is one of the most distinct features of the dendritic macromolecules. Poly(benzyl ether) (PBE) dendron [1] has been studied most extensively as an efficient antenna dendron. Careful studies have revealed the crucial role of the symmetric dendritic structure for the antenna effect. 

Fig. 3. A large multiporphyrin array arranged in a dendritic scaffold...

The preparation of biocompatible SWNTs, noncovalently functionalized with bioactive glycodendrimers, has been reported (Scheme 29).253 A bifunctional dendritic scaffold 284 was built using the 2,2-bis(hydroxymethyl)propanoic acid as a building block 281, which was linked to an azidopyrene tail (280) capable of binding the surface... 

Scheme 1 Sialoside precursors having varied functionalities for direct attachment to hyperbranched or dendritic scaffolds...

For the synthesis of perfectly dendronized sohd-phase polymers (Fig. 7.4) various dendritic structures were prepared based on amide connections [6]. For example, the naturally occurring amino acid lysine was used as a building block in creating a dendritic scaffold [33]. The synthesis of symmetrical tri-branching den-drimers on aminomethyl polystyrene macrobeads was also described in literature [34]. Recently, aryl ether dendrimers were prepared on hydroxymethyl polystyrene using a Mitsunobu reaction with 3,5-bis(acetoxymethyl)phenol [35]. 

Ligand Dendritic Scaffold Metal Reaction Metal/Substrate Conversion (%) Recovery Method Comment Rejs. 

In the case of complex dendrimers with differing branches or differing dendryl substituents on a non-dendritic scaffold it is necessary to include further details in the name. For this reason, a more detailed cascadane nomenclature [45] has been developed, according to which the above POPAM would be called ... 

Fig. 8.17 Cadomer 24 (schematic) 24 gadolinium ions (green) are bound in 24 peripherally attached cyclen ligands 18 lysine units form the dendritic scaffold. The molar mass is 17 kDa...

There is also a lack of straightforward standard and low-cost syntheses for higher generations of certain dendritic scaffolds, such as those in which nitrogen atoms are responsible for branching. As our knowledge of dynamic non-... 

Scheme 4.12. Lysine-based dendritic scaffolding used for the preparation of polyimmunogens.

---