Peracetic acid, disinfectant

Lomas, R. J., L. M. Jennings, J. Fisher, and J. N. Kearney. 2004. Effects of a peracetic acid disinfection protocol on the biocompatibility and biomechanical properties of human patellar tendon allografts. Cell and Tissue Banking 5(5)(5V) 149-160. 

Peracetic Acid. Peracetic acid (peroxyacetic acid) [79-21-0] the peroxide of acetic acid, is a disinfectant having the desirable properties... 

Peptizers, in tire compounding, 21 810 Pepto-Bismol, 4 36 Peptone, killing rate of e. coli, 8 64It Peracetic acid, 21 46-47 disinfection via, 8 630 production from acetaldehyde, 1 102, 111 Peracids, 9 369-370, 370-371, 372 10 378, 380... 

Uses Manufacture of acetic acid, acetic anhydride, aldol, aniline dyes, 1-butanol, 1,3-butylene glycol, cellulose acetate, chloral, 2-ethylhexanol, paraldehyde, pentaerythritol, peracetic acid, pyridine derivatives, terephthalic acid, trimethylolpropane, flavors, perfumes, plastics, synthetic rubbers, disinfectants, drugs, explosives, antioxidants, yeast silvering mirrors hardening gelatin fibers. 

The most common disinfectants in use nowadays are sodium hypochlorite, peracetic acid, ammonium quaternary salts, aldehydes, alcohols and phenol compounds. However, according to [25], all disinfectants require special attention. Indeed, glutaraldehyde, used widely in the past but now generally discarded in favour of compounds with a smaller impact on WWTP biological processes, has been found in concentrations ranging from 0.5 to 3.72 mg [15]. Moreover, triclosan, a common detergent and antimicrobial agent found in many personal care... 

The peroxygen compounds, hydrogen peroxide and peracetic acid, have high killing activity and a broad spectrum against bacteria, spores, viruses, and fungi when used in appropriate concentration. They have the advantage that their decomposition products are not toxic and do not injure the environment. They are powerful oxidizers that are used primarily as disinfectants and sterilants. 

Sterilization of a membrane system is also required to control bacterial growth. For cellulose acetate membranes, chlorination of the feed water is sufficient to control bacteria. Feed water to polyamide or interfacial composite membranes need not be sterile, because these membranes are usually fairly resistant to biological attack. Periodic shock disinfection using formaldehyde, peroxide or peracetic acid solutions as part of a regular cleaning schedule is usually enough to prevent biofouling. 

Peracetic acid is a particularly powerful biocide used for disinfection of raw or partially treated sewage effluents and sewage sludge. Peracetic acid can also be successfully used for the disinfection of drinking water.50... 

Peracetic acid is the most widely used organic peroxy acid. It is a strong oxidizer, which could he used in disinfection and bleaching agent. Peracetic acid can be synthesized from acetic acid and hydrogen peroxide. The formation of peracetic acid takes place in the equilibrium reaction (1). In order to accelerate the reaction rate, acid catalyst is needed (Swem, D., 1970). Conventionally homogeneous sulphuric acid catalyst is used. The reaction scheme is shown in Eq. (1)... 

Pettas, LA. and Karayannis, M.I. (2004) Simultaneous spectra-kinetic determination of peracetic acid and hydrogen peroxide in a brewery cleaning-in-place disinfection process. Anal... 

Copper 8-quinolinolate disinfectant, antiseptic shampoo Cetethyidimonium bromide disinfectant, antiseptic toothpastes Cetethyidimonium bromide disinfectant, beverage equipment Peracetic acid... 

Biological Iron reducing bacteria, sulphur reducing bacteria, mycobacteria, pseudomonas EDTA or BIZ type detergents at high pH shock disinfection with hydrogen peroxide, peracetic acid... 

The CIP system is used for chemical sanitising also. Disinfection was discussed in Section 2.2. The most common chemical disinfectants are chlorine, hydrogen peroxide and peracetic acid. 

The fresh water for the bottle rinsing and cooling is another miaobiological risk point. Microbiological control of the fresh water is essential to avoid any re-contamination of the bottle after cleaning. Disinfection with, for example, chlorine dioxide or peracetic acid is used to reduce the risk of microbiological infection in the rinsing zones. 

In the special case of aseptic filling, it may be necessary to decontaminate the PET bottles before filling. Usually hydrogen peroxide or peracetic acid is used for disinfection. Aseptic filling is not necessary for filling beer and beer products. 

More innovative but less successful innovations in line cleaning include novel approaches such as the use of ozone, chlorine dioxide and peracetic acid. Although these are well-accepted approaches in (brewery) CiP disinfection, none have made an impact on dispense line cleaning, although, pleasingly, ozone has at least been evaluated under controlled conditions (Fielding et al., 2007). 

Crebelli, R. et al., Genotoxicity of the disinfection by-products resulting from peracetic acid or hypochlorite disinfected sewage wastewater, Wat. Res., 39, 1105, 2005. 

Before working the inside of the isolator has to be cleaned and disinfected. Disinfection can be done with peracetic acid or hydrogen peroxide, using special disinfection devices and procedures. For small scale or incidental use ethanol 70-80 % may be used as an alternative. 

The few publications which discuss the action of peracetic acid against drinking water or wastewater biofilms suggest that practice-relevant concentrations of peracetic acid cause a relatively fast and effective inactivation of biofilm bacteria, but result in no or minimal removal of the biofilm under these conditions. This is considered to be a disadvantage for at least the drinking water area, where residual biofilm material on surfaces can promote recontamination of the water (Exner et al., 1987 Morin, 2000). In this context, Mathieu et al. (1990) reported that the discontinuous application of peracetic acid led to an incomplete disinfection and dissolution of biofilms, but nevertheless can significantly limit the extent of biofilm development. 

Sanchez-Ruiz, C., Martinez-Royano, S. and Tejero-Monzon, I., 1995. An evaluation of the efficiency and impact of raw wastewater disinfection with peracetic acid prior to ocean discharge. Water Science and Technology 32, 159-166. 

Wutzler, P. and Sauerbrei, A., 2000. Viricidal efficacy of a combination of 0.2% peracetic acid and 80% (v/v) ethanol (PAA-ethanol) as a potential hand disinfectant. Journal of Hospital Infection 46, 304-308. 

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