Particle Sizing Systems

Partikel Messtechnik (PMT) manufacture a range of microprocessor controlled 16 and 32 channel analyzers. 

PMT-2120 counter uses light blockage and can count up to 3,000 particles per second. It covers the size range 1-12,000 pm with selectable 16 or 32 channels. 

Particle Sizing Systems (PSS) is a designer and manufacturer of particle sizing instruments that are used for research and development, USP quality assurance, contamination and in-line monitoring. 

PSS Accusizer 780/SPOS Single particle optical sizer consists of a patented autodilution stage, single particle optical sensor, pulse height analyzer/counter (PHA), systems computer/processor and software control. The autodiluter performs a continuous dilution of the concentrated sample 

A syringe injection sampler, the 780/SIS, which includes 32 user-defined channels that can be converted to 512 channels to give contamination monitoring and particle size analysis in a single system. 

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Optical counters have been widely used to monitor cleanroom technology and particles in oil. Instmments manufactured by Royco Inc. (Menlo Park, California) are available for studying aerosols and particles in Hquids. The HIAC counter (HIAC Instmments, Monte Claire, California) is a widely used stream counter for particles in fluid. One of the more recently developed optical counters is available from Particle Sizing Systems (Santa Barbara, California). The configuration of one of the widely used counters, the Climet counter, is shown in Figure 16. A general review of photozone counters is available (3). 

Fig. 10. Large particle distribution for abused silica slurry (Courtesy of Particle Sizing Systems).

Figure 4. Volume-weighted particles size distribution of calcined MSU-1 Silica obtained with Tergitol 15S12. Particle sizing was performed with an Accusizer 770A (NICOMP, Particle Sizing Systems Co (CA, USA)).

AccuSizer, Particle Sizing Systems Co., 75 Aero Camino, Santa Barbara, California, 93117. 

Figure 2 Zeta potential of DNA-protamine sulfate complexes. Plasmid DNA was condensed with protamine sulfate in increasing ratios (w/w). The surface charge (zeta-potential) was determined using a Nicomp 380 ZLS Zetasizer (Particle Sizing Systems, Santa Barbara, CA).

Effect of Bisphenol A Addition Two-Particle Size Systems. If we modify the Hycar CTBN-epoxy resin system so as to produce a two-particle size system, we can produce the toughest epoxy resins. We modified the CTBN-epoxy resin system by adding bisphenol A. A many-fold improvement in fracture energy is obtained when Hycar CTBN is used with bisphenol A and epoxy resin. The maximum improvement, when 5 phr Hycar CTBN is used, is at a bisphenol A concentration of 24 parts per hundred parts of epoxy resin. Typical data describing the properties of these systems are shown in Table VI. 

Particle-Sizing Systems Inc. Accusizer size-range. Available at http //www.pssnicomp.com/acculab.htm. 

Particle size measurements were made using an UV-laser, shadow photographic technique. The particle sizing system displayed real-time droplet images onto a television monitor. The images (shadows) were obtained when a pulsed (30 times per second) UV-laser beam was directed through a spray scene onto a synchronized UV-sensitive vidicon camera/recorder. The narrow depth of field used by this system can record shadows from 300 in-focus droplets per second with a resolution down to approximately 0.3 /un in diameter. 

Fig. 9.12 Schematic diagram of the Particle Sizing Systems Accusizer autodilution apparatus and optical particle counter.

Nicomp Model 380/L is designed for on-line monitoring either by itself or in combination with the Particle Sizing System AccuSizer. These instruments are available from Particle Sizing Systems. 

Nicomp Particle Sizing Systems, 75 Aero Camino, Suite B, santa Bardera, CA 93117, USA, (805) 968 1497... 

Particle Sizing Systems, 75 Aero Camino, Santa Barbara, CA 93117, (805)968-1497Pascall Ltd, Gat wick Road, Crawley, Sussex, RHIO 2RS, UK Pascal Ltd.,Gatwick Road, Crawley, Sussex, RHIO 2RS, UK PenKem(now Dispersion Technology)... 

Mean hydrodynamic diameters of vesicles (liposomes, nanospheres, nanobeads) can be determined by dynamic laser light scattering, e.g. the NICOMP 380 particle sizing instrument, Particle Sizing Systems (Sta. Barbara, CA, USA). 

Figure 19.6 Schematic illustration of light-diffraction particle sizing system.

Photon correlation spectroscopy has several important features, most notably the duration of the experiment is short, and it is readily automated so that reliable measurements can be made even by inexperienced operators. The method has modest development costs. Commercial particle sizing systems mostly operate at only one angle (90°) and use red light (wavelength, 675 nm). Usually in these systems the dependence of light-scattering intensity on concentration is neglected. 

Some of these develc nnents are st towards "in-line or on-line analysis [128-131]. Malvern offers a Master Sizer (36(X) EQ for this use, as does Particle Sizing Systems (NKTOMP 370 L), and Leeds Nordmip (Micro Trac SRA-1(X)). Insitec markets three specific in-line instrum its for particle measurement in the range 0.5-1500 pm, but these are used primarily on powdered materials or... 

In Table 12.2, the averages d , d i, ds, and distribution data are available then it is posable to compute any die particle size averages. 

Figure 12.13 Auto-dilution and optical particle sensor schematic of the Accusizer 770, where MC = mixing chamber, Vi, Vi, V3 = valves, P = pump, OPS = optical particle sensor, LS = laser source, D = detector, V s volts and PHA = pulse height analyser. (Courtesy of Particle Sizing Systems.)...

As well as the chemical testing, inhalers require specific characteristics to be determined. Dose delivery and number of doses and particle size, which is crucial for delivery to the lung, should be determined. The testing for inhalers is a labor-intensive activity. The robustness of the delivery, number of doses and particle size, system, the container and valve seal, and propellant losses are all determined. 

Orlando, FL., Fall 1996, p.34-5. 012 HIGH-RESOLUTION PARTICLE SIZE ANALYSIS OF MOSTLY-SUBMICRON EMULSIONS BY SIMULTANEOUS COMBINATION OF DLS AND SPOS McKenzie C D Wn J S Chang Y J O Hagan P Hasapidis K Particle Sizing Systems... 

The Particle Sizing System (PSS) AccusizerLPC Is Available for Both Bench-top Bottle Sample Measurement and On-line Semi-continuous Particle Measurement (see http // pssnicomp.com/products/accusizer last accessed November 2014). 

Solution 3.12 In principle, the particle-sizing system should be able to find the distribution of molecular weig M of a polymer in solution. Assume a narrow distribution of M around M given by... 

Goossens et al. (1971) modified the equation by Wen and Yu (1966b) on the minimum fluidization velocity for single particle size systems by substituting with the mixture particle density, pp, and the mixture particle size, d , of a binary mixture as follows ... 

The particle size analysis of the powder after crushing for 2 h with the assistance of a planetary crusher at a rate of 250 revolutions/min and calibrated with 100 mm was determined using a Particle Sizing Systems (Inc. Santa Barbara, California, USA Model 770 AccuSizer). The particle diameters range varied from 0.5 to 54 mm (Fig. 2). 

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