Oleanolic glycosides

Matsuda H, Dai Y, Ido Y, et al. Studies on Kochiae fiructus. V. Antipruritic effects of oleanolic acid glycosides and the structure-requirement. Biol Pharm Bull 1998 21 1231-1233. 

Licania pittieri Prance is a tree up to 15 meters high growing in the cloud forests at 1800 m in altitude. From the methanol extract of the leaves, collected in the Parque Nacional Henry Pittieri, oleanolic acid (1), ursolic acid (2), catechin (3), epicatechin (4), quercetin (5), and four glycosidic derivatives, quercetin 3-O-P-D-galactopyranoside (6), quercetin 3-O-P-D-glucopyranoside (7), quercetin 3-O-a-L-rhamnopyranoside (8), and quercetin 3-O-a-L-arabinopyranoside (9) were identified directly by comparing their spectroscopic data with those reported in the literature and/or authentic samples [see Fig. (1)] [5]. 

Oleanolic acid glycosides Chenopodium quinoa (quinoa) Bitter... 

The satire approach was used for the structural determination of five oleanolic acid glycosides from Calendula arvensis 32-36 (23) and 3p, 2ip, 23 trihydroxy-olean-12-en-28-oic acid bisglycoside 44... 

The flowers contain triterpenoid glycosides based on oleanolic acid, sesquiterpenes, carotenoids and flavonoids. Infusions and tinctures are used topically for inflammations of the skin and to promote wound healing (cicatrisation). 

An inhibitory effect against VSV multiplication was observed for five oleanolic acid glycosides from Calendula arvensis while rhinovirus (HRV) replication was significantly affected by only one compound, a bidesmosidic triglycoside of oleanolic acid [157],... 

Some saponins have been reported to present potent sedative activity. Namely, two jujubogenin -3-O-glycosides from Colubrina asiatica [211] and oleanolic acid glycosides from Cussonia barteri significantly inhibited the spontaneous motility of the mice even at low doses (lmg/kg) [212]. The colubrinosides showed an antagonistic effect on amphetamine and exerted a synergistic activity on chlordiazepoxide [211]. 

Ginsenoside R oleanolic acid a.s aglycone The glycosides contain glucose, arabinose, rhamnose and glucuronic acid HI (drug) < 1000... 

The bisdesmosidic tritcrpene glycosides of oleanolic and 28-hydroxy-oleanolic acids, such as hederacoside B and C, are found as dark grey-blue zones in the lower R, range... 

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