O-dinitrophenol

Other Names P-Dinitrophenol 2,6-DNP 2,6-Dinitrophenol NSC 6215 Phenol, P-dinitro- o-Dinitrophenol... 

Landsteiner and Jacobs (1935) chose 1-2,4 chlordinitrobenzene and other derivatives of benzene for their work on the sensitization of guinea pigs. This eczematogenic substance had already been used by Wedroff (1933) in man. A very close derivative, O-dinitrophenol, was known to be a frequent cause of allergy in workers handling this substance (Frumess, 1934). 

The nitration of anisole in 40% aq. nitric acid in the presence of some nitrous acid yielded 2,4-dinitrophenol as the main product. In more concentrated solutions of nitric acid 0- and />-nitroanisoles were the main products, less than o-1 % of the weta-isomer being formed. " The isomeric ratios for nitration imder a variety of conditions are given later ( 5.3.4). 

The procedure of simultaneous extracting-spectrophotometric determination of nitrophenols in wastewater is proposed on the example of the analysis of mixtures of mono-, di-, and trinitrophenols. The procedure consists of extraction concentrating in an acid medium, and sequential back-extractions under various pH. Such procedures give possibility for isolation o-, m-, p-nitrophenols, a-, P-, y-dinitrophenols and trinitrophenol in separate groups. Simultaneous determination is carried out by summary light-absorption of nitrophenol-ions. The error of determination concentrations on maximum contaminant level in natural waters doesn t exceed 10%. The peculiarities of application of the sequential extractions under fixed pH were studied on the example of mixture of simplest phenols (phenol, o-, m-, />-cresols). The procedure of their determination is based on the extraction to carbon tetrachloride, subsequent back-extraction and spectrophotometric measurement of interaction products with diazo-p-nitroaniline. 

Dimethyl sulfate, 57 Dimethyl sulfide, 57 Dimethyl sulfoxide, 57 Dimethyl terephthalate, 57 Dimetilan, 57 Dinitroanilines, 57 Dinitrobenzenes, 58 Dinitrolmide, 58 Dinitronaphthalenes, 58 Dinitro-o-Cresol, 58 Dinitrophenols, 58... 

Dinitrophenol (DNP) gives a single wave in NPV and a pair of anodic and cathodic peak currents in CV at the NB/W interface in pH range studied. Figure 7 shows a cyclic voltammogram of 0.6 mM DNP (NB) at O.IM TPenATPB (NB)-O.IM LiCl, 50 mM phosphate buffer, pH 6.3 (W), that can be assigned to one-proton transfer assisted by A present in NB. The E]j2 vs. pH plot is shown in Fig. 8, in which the results obtained with... 

At first we determined, by means of the DVP method, ifTMAX of 2,4-dinitro-phenolate, 2,5-dinitrophenol picrate, acetate and benzoate, which lay between 10 3 and 10 5. Next, separate potentiometric titrations of 2,5-dinitrophenol and picric acid were carried out on the basis of the previously known (see above) ptfax = 6.5 and P hx2- = 100 for 2,5-dinitrophenol and p.fiTHX = 3.0 for picric acid, we calculated titration curves for estimated values of 0 and obtained, for the best fit between the experimental and calculated curves, K o = 10 21 for both 2,5-dinitrophenol and picric acid. In both instances changing fTMA0H for 1 to 10 6 did not alter the calculated titration curve. Finally, for potentiometric titrations of other acids with TMAOH while using / TMAX values from DVP results, in addition to Kn 0 = 10 21, we obtained the best fit between the experimental and calculated curves again when pifbenzoic acid = 1 (see Fig. 4.12)... 

Dinitrophenol 4,6 -Dinitro-o -cresol V-Nitrosodimethylamine V-Nitrosodiphenylamine V-Nitrosodi-n-propylamine Pentachlorophenol Phenol... 

Interaction in THF gives 2,4-dinitrophenol and ammonia, and on one occasion a violent detonation occurred potassium dinitrophenoxide may have been involved. See Sodium 2,4-dinitrophenoxide See other n-o compounds, polynitroaryl compounds... 

Polarographic studies of a mitochondrial fraction from Hymenolepis diminuta showed that of four substrates tested, DL-glycerol-3-phosphate was the most rapidly oxidized, but the highest respiratory control ratio (1.7) was obtained with dl-isocitric acid. With isocitrate as substrate oxyclozanide at 1.61 nM stimulated O uptake and relieved oligomycin inhibition of adinosine diphosphate-stimulated respiration, but at concentrations above 2 pM progressively inhibited O uptake. Rafoxanide, niclosamide, 3,4,5-tribromo-salicylanilide, nitroxynil, resorantel, di-chlorophen, and 2,4-dinitrophenol exhibited effects similar to those of oxyclozanide on the respiration in cestode mitochondria. The relative potencies were compared and the possible mode of action discussed [38]. 

By further nitration with more concentrated acid o- and p-nitro-phenols are converted into the same 2 4-dinitrophenol, and finally into picric acid. Polynitro-derivatives of benzene, such as picric acid and trinitrotoluene, can be caused to explode by detonation with mercury fulminate or lead azide. (The formulae of these two compounds should be written.) They are endothermic, i.e. the oxygen of the nitro-group can oxidise carbon and hydrogen within the molecule and heat is liberated. This intramolecular combustion is rather considerable in the case of picric acid, which is decomposed in accordance with the equation ... 

Since mtro-groups in the o- and p-positions increase the mobility of halogens directly attached to the aromatic ring (p. 106), nitrophenols can also be obtained from chloronitrobenzenes. Thus p-chloronitro-benzene can be decomposed by alkalis in the autoclave, and 2 4-dinitrophenol, an important intermediate product for the manufacture of sulphur dyes, is produced from the corresponding chlorobenzene by an even milder treatment. 

The electrochemical behavior of the components of a commercial plant growth stimulator (Sviton) was studied. This included determination of o-nitrophenol, p-nitrophenol, 2-methoxy-5-nitrophenol and 2,4-dinitrophenol by differential pulse voltammetry at a hanging mercury drop electrode. The optimum conditions were established for their quantitation over the 1 x 10 7 to 1 x 10-5 M range516. 

Titanium ions can also he used as redox catalysts for the indirect cathodic reduction of nitro compounds (417). The electroreduction is carried out in an H20-H2S04/Ti(S04)2-(Pb/Cu) system at 45 80°C under 5 20Am . Nitrobenzene, dinitrobenzene, nitrotoluene, 2,4-dinitrotoluene, 2-nitro-m-xylene, nitro-phenol, 2,4-dinitrophenol, nitrophenetole, o-nitroanisole, 4-nitrochlorotoluene, ni-trobenzenesulfonic acid, and 4,4 -dinitro-stilbene-2,2 -disulfonic acid can all be reduced by this procedure to the corresponding amino compounds (418) in good yields (Scheme 146) [513-516]. Tin... 

AI3-00040, see Cyclohexanol AI3-00041, see Cyclohexanone AI3-00045, see Diacetone alcohol AI3-00046, see Isophorone AI3-00050, see 1,4-Dichlorobenzene AI3-00052, see Trichloroethylene AI3-00053, see 1,2-Dichlorobenzene AI3-00054, see Acrylonitrile AI3-00072, see Hydroquinone AI3-00075, see p-Chloro-rrr-cresol AI3-00078, see 2,4-Dichlorophenol AI3-00085, see 1-Naphthylamine AI3-00100, see Nitroethane AI3-00105, see Anthracene AI3-00109, see 2-Nitropropane AI3-00111, see Nitromethane AI3-00118, see ferf-Butylbenzene AI3-00119, see Butylbenzene AI3-00121, see sec-Butylbenzene AI3-00124, see 4-Aminobiphenyl AI3-00128, see Acenaphthene AI3-00134, see Pentachlorophenol AI3-00137, see 2-Methylphenol AI3-00140, see Benzidine AI3-00142, see 2,4,6-Trichlorophenol AI3-00150, see 4-Methylphenol AI3-00154, see 4,6-Dinitro-o-cresol AI3-00262, see Dimethyl phthalate AI3-00278, see Naphthalene AI3-00283, see Di-rj-butyl phthalate AI3-00327, see Acetonitrile AI3-00329, see Diethyl phthalate AI3-00399, see Tributyl phosphate AI3-00404, see Ethyl acetate AI3-00405, see 1-Butanol AI3-00406, see Butyl acetate AI3-00407, see Ethyl formate AI3-00408, see Methyl formate AI3-00409, see Methanol AI3-00520, see Tri-ocresyl phosphate AI3-00576, see Isoamyl acetate AI3-00633, see Hexachloroethane AI3-00635, see 4-Nitrobiphenyl AI3-00698, see IV-Nitrosodiphenylamine AI3-00710, see p-Phenylenediamine AI3-00749, see Phenyl ether AI3-00790, see Phenanthrene AI3-00808, see Benzene AI3-00867, see Chrysene AI3-00987, see Thiram AI3-01021, see 4-Chlorophenyl phenyl ether AI3-01055, see 1.4-Dioxane AI3-01171, see Furfuryl alcohol AI3-01229, see 4-Methyl-2-pentanone AI3-01230, see 2-Heptanone AI3-01231, see Morpholine AI3-01236, see 2-Ethoxyethanol AI3-01238, see Acetone AI3-01239, see Nitrobenzene AI3-01240, see I idine AI3-01256, see Decahydronaphthalene AI3-01288, see ferf-Butyl alcohol AI3-01445, see Bis(2-chloroethoxy)methane AI3-01501, see 2,4-Toluene diisocyanate AI3-01506, see p,p -DDT AI3-01535, see 2,4-Dinitrophenol AI3-01537, see 2-Chloronaphthalene... 

Dinitro-2-methylphenol, see 4.6-Dinitro-o-cresol a-Dinitrophenol, see 2,4-Dinitrophenol Dinitrosol, see 4,6-Dinitro-o-cresol Dinitrotoluol, see 2,4-Dinitrotoluene... 

Dinitrotoluol, see 2,6-Dinitrotoluene Dinoc, see 4,6-Dinitro-o-cresol Donofan, see 2,4-Dinitrophenol Dinopol NOP, see Di-n-octyl phthalate Dinoxol, see 2,4-D, 2,4,5-T Dinurania, see 4,6-Dinitro-o-cresol Dioctyl-o-benzenedicarboxylate, see Di-/ -octyl phthalate Dioctyl phthalate, see Bis(2-ethylhexyl) phthalate. Di-n-... 

DNOC, see 4,6-Dichloro-o-cresol DNOP, see Di-n-octyl phthalate DNP, see 2,4-Dinitrophenol... 

Methyl-l,3-dinitrobenzene, see 2,6-Dinitrotoluene 2-Methyl-4,6-dinitrophenol, see 4,6-Dinitro-o-cresol 6-Methyl-2,4-dinitrophenol, see 4,6-Dinitro-o-cresol... 

Nitric acid, see 1-Butene, o-Chloronitrobenzene. p-Chloronitrobenzene, Chloropicrin, 2,3-Dichloronitrobenzene. 3.4-Dichloronitrobenzene. 2,4-Dinitrophenol, Formaldehyde, Isopropylbenzene, Methanol, Methyl mercaptan, 2-Methylphenol, 2-Methylpropene, Methyl sulfide. Nitrobenzene, 2-Nitrophenol, 4-Nitrophenol,... 

Direct amination of benzo[l,2-aqueous base with hydroxylamine-0-sulfonic acid gives a mixture of three diamino derivatives and two monoamino derivatives (Equation (15)). The combined yields of diamino and monoamino products are 45% and 48%, respectively. The three diamino derivatives can be separated by fractional crystallization from ethanol <86JOC979>. A-Amination of triazoles can also be achieved by treatment with NaH in DMF followed by O-amino-2,4-dinitrophenol <85TL335> or 0-(mesitylsulfonyl)hydroxyamine (9lJCS(Pl)2045>. 

Ad 41) L.A. Burrows W.E. Lawson, USP 2175250(1939) (Electric detonators using combustible element comprising of Pb salts of dinitrophenol, mononitroresorcinol, or dinitro-o-cresol also lead nitrato-bis basic lead dinitro-o-cresylate) Ad 4la)... 

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