Neuropathy caused

Chamouard JM, Smadja D et al (1993) [Neuropathy caused by necrotizing vasculitis in HIV-1 infection]. Rev Neurol (Paris) 149(5) 358-361... 

JohnsonMK. 1975. The delayed neuropathy caused by some organophosphorus esters Mechanism and challenge. Crit Rev Toxicol 3 289-316. 

Two allelic trembler mutations, which affect only the PNS, result from different point mutations in transmembrane domains of peripheral myelin protein-22 (PMP-22) [1,45] (Table 4-2). The trembler phenotypes are characterized by hypomyelination, continued Schwann cell proliferation and partial paralysis of the limbs. These murine mutants are animal models for some of the inherited human neuropathies caused by abnormalities of the... 

The major toxic effect of exposure to 2-hexanone is neuropathy. Neuropathy can be caused by both 2-hexanone and its metabolite 2,5-hexanedione. A reduction of the neuropathy caused by exposure to 2-hexanone could theoretically be achieved through shunting of metabolism to less toxic metabolites. However, as discussed above, the toxicity of those other metabolites, and the effect of the treatment on metabolism of other potential toxicants, would have to be clearly assessed. 

Davenport JG, Farrell DF, Sumi SM. 1976. Giant axonal neuropathy caused by industrial chemicals Neurofilamentous axonal masses in man. Neurology 26 919-923. 

LHON (Leber s hereditary optic neuropathy) causes blindness arising from mutations in the ND1 gene encoding complex I of the electron transport chain (see Chapter 7). 

Aliphatic hydroxylation. As well as unsaturated aliphatic compounds such as vinyl chloride mentioned above, which are metabolized by epoxidation, saturated aliphatic compounds also undergo oxidation. The initial products will be primary and secondary alcohols. For example, the solvent n-hexane is known to be metabolized to the secondary alcohol hexan-2-ol and then further to hexane-2,5-dione (Fig. 4.9) in occupationally exposed humans. The latter metabolite is believed to be responsible for the neuropathy caused by the solvent. Other toxicologically important examples are the nephrotoxic petrol constituents, 2,2,4- and 2,3,4-trimethylpentane, which are hydroxylated to... 

Vik H, Andersen KJ, Julshawn K, et al. 1985. Neuropathy caused by silver absorption from arthroplasty cement [letter]. Lancet, April 13 1(8433) 872. 

A neuropathy caused by clioquinol (iodochlorohydroxyquin, chinoform) and enhanced by the formation of a clioquinol ferric chelate which initiates lipid peroxidation, leads to complete degeneration of retinal neuroblasts within a day. Vitamin E has a potent protective action against the effects of the chelate [75]. Peroxidative damage to DNA in rat brain, induced by methyl ethyl ketone peroxide, a potent initiator of lipid peroxidation, was inhibited by addition of vitamin E to the diet of rats [76]. 

B16. Bjokenheim, B., Optic neuropathy caused by vitamin BI2 deficiency in carriers of the fish tapeworm Diphyllobothrium latum. Lancet 1, 688-690 (1966). 

Merkies IS, Schmitz PI, Samijn JP, van der Meche EG, van Doom PA (1999) Fatigue in immune-mediated polyneuropathies. Europeau Inflammatory Neuropathy Cause aud Treatmeut (INCAT) Group. Neurology 53 1648-1654. 

Gupta R, Singh S, Tang R, Blackwell TA, Schiffman JS. Anterior ischemic optic neuropathy caused by interferon alpha therapy. Am J Med 2002 112(8) 683. ... 

Miller B, Skupin A, Rubenfire M, Bigman O. Respiratory failure produced by severe procainamide intoxication in a patient with pre-existing peripheral neuropathy caused by amiodarone. Chest 1988 94(3) 663-5. 

Friedman MA, Resnick IS, Baer RL. Subepidermal vesicular dermatosis and sensory peripheral neuropathy caused by pyridoxine abuse. J Am Acad Dermatol 1986 14(5 Pt 2) 915-17. 

Morra M, Philipszoon HD, D Andrea G, et al. (1993) Sensory and motor neuropathy caused by excessive ingestion of vitamin Bg A case report. Functional Neurology 8(6) 429—432. 

Merkies IS, Schmitz PI, van der Meche FG, Inflammatory Neuropathy Cause and Treatment (INCAT) Group et al (2000) Psychometric evaluation of a new sensory scale in immune-mediated polyneuropathies. Neurology 54 943-949... 

Inherited sensory neuropathies caused by mutations in different genes (HSN l-V)... 

Heyman A, Pfeiffer JB, Willett RW, et al Peripheral neuropathy caused by arsenical intoxication. N Engl J Med 254 401-409, 1956 Jenkins RB Inorganic arsenic and the nervous system. Brain 89 479-498,1966 Krainer L, Black DAK, McGill RJ, et al Arsenical encephalopathy in Indian troops. 

Peripheral neuropathy causing muscle weakness and sensory loss... 

Swelling and necrosis of cells edema of myelin sheaths in CNS Delayed neuropathy, causing paralysis of muscles... 

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