Vomiting and nausea in pregnancy

Ruangsri. Ginger for nausea and vomiting in pregnancy randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001 97(4) 577-582. 

Dicycloverine was formerly combined with doxylamine succinate and sometimes with pyridoxine in Debendox (Bendectin) tablets, which were used in certain countries for the treatment of nausea and vomiting in pregnancy. There has been a widely discussed suggestion... 

Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 2003 189 1374-1377. 

The H, antagonists are used to treat allergic reactions, motion sickness, vertigo, nausea and vomiting in pregnancy, preoperative sedation, and in over-the-counter sleeping pills. 

Smith, C., C. Crowther, K. Willson, N. Hotham, and V. McMUlian. 2004. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet. Gynecol. 103(4) 639-645. 

Effectiveness of acupuncture and acupressure for nausea and vomiting of pregnancy has not been clearly proven in clinical studies, but both methods are safe to recommend.10,16 Benefits may include a reduction in nausea and dry heaving but not in vomiting.10... 

Hyperemesis gravidarum A rare disorder of severe and persistent nausea and vomiting during pregnancy that can result in dehydration, malnutrition, weight loss, and hospitalization. 

Antiemetic (parenteral only) - In controlling nausea and vomiting (excluding nausea and vomiting of pregnancy). As pre- and postoperative and pre- and postpartum adjunctive medication to control emesis. 

Nausea and vomiting in early pregnancy should be managed in the first place by reassurance, attention to emotional factors, and general measures such as a cup of tea and biscuit, and light and frequent meals with adequate fibre intake. In resistant cases, drug therapy may be necessary. 

Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2003. 

Backon J. Ginger in preventing nausea and vomiting of pregnancy a caveat due to its thromboxane synthetase activity and effect on testosterone binding [letter]. Eur J Obstet Gynecol Reprod Biol 1991 42 163-164. 

It is mainly used as an antiemetic in the prevention and treatment of motion sickness. It may also he used in post-operative vomiting, the nausea and vomiting of pregnancy, drug-induced nausea and vomiting and in irradiation sickness. 

Chittumma, R, K. Kaewkiattikim, and B. Wiriyasiriwach. 2007. Comparison of the effectiveness of ginger and vitamin for treatment of nausea and vomiting in early pregnancy A randomized double-bUnd controlled trial. J. Med. Assoc. Thai. 90(l) 15-20. 

Sripramote, M., and N. Lekhyananda. 2003. A randomized comparison of ginger and vitamin B in the treatment of nausea and vomiting of pregnancy. /. Med. Assoc. Thai. 86 846-853. 

Bryer, E. 2005. A literature review of the effectiveness of ginger in alleviating mild-to-moderate nausea and vomiting of pregnancy. /. Midwifery Womens Health 50 (l) el-3. 

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