Nandrolone 19-nortestosterone

Nandrolone (19-Nortestosterone) Injection sites HPLC Extract with tetrahydrofuran Lichrosorb, C-18, 5 m... 

Bulk Nandrolone (19-Nortestosterone) TLC Dissolve in water, pH 5.5-9.0, extract with CHCI, Silica (activated) MeOH-ammoniated butanol, butanol prepared by shaking 100 ml butanol with 60 ml NH4OH, discard 1% lower layer Ferric chloride USP 23 [2,3,10,958, 1133,1134] [5]... 

For drug therapy, native hormones have been replaced to a large extent by synthetic or semisynthetic derivatives that possess higher and more selective therapeutic potential. Some very important synthetic androgen analogs are the esters and the 17-methyl derivative of testosterone. Of the numerous related anabolic steroids, the esters of nandrolone (19-nortestosterone), methandienone (17a-methyl-17-hydroxy-l,4-androstadien-3-one), stanozolol (17a-methyl-2 H-5a-androst-2-eno[3,2-c]pyrazol-17-ol, and trenbolone acetate (17)S-hydroxy-4,9,ll-estratrien-3-one acetate) are most frequently used. 

Nandrolone (19-nortestosterone, Fig. 4.5, 6) lacks the C-19 methyl residue of testosterone, a fact that causes a considerable change of the dissociation behavior of protonated molecules compared to the 3-keto-androst-4-ene-derived steroids. While the ion at m/z 109 is still observed, the fragmentation of the positively charged species yields many additional abundant product ions, but the diagnostic fragment ion at m/z 97 is not detected due to the lack of the C-19 residue (Fig. 4.6c). 

Chemical Name 170-hydroxyestr-4-en-3-one 3-phenylpropionate Common Name 19-nortestosterone (3-phenylpropionate Structural Formula See Nandrolone Decanoate for the steroid structure Chemical Abstracts Registry No. 62-90-8 434-22-0 (Base)... 

Anabolic activities of testosterone, such as increases in amino acid incorporation into protein and in RNA polymerase activity, have been demonstrated in skeletal muscle. Apart from the direct anabolic effects in specific tissue, androgens antagonize the protein catabolic action of glucocorticoids. The androgen compounds with the greatest ratio of protein anabolic effects to virilizing effects are the 19-nortestosterone derivatives. Compounds that are used clinically (Table 63.3) include nandrolone phenpropionate (Durabolin), nandrolone decanoate... 

Nortestosterone, or Nandrolone as it is more commonly known, is a deviation of the testosterone molecule that results in a highly anabolic/moderately androgenic AAS. Additionally, Nandrolone is very protein sparing and liver friendly according to the drug insert literature. 

Le Bizec et al. [64] demonstrated the detection of 19-norandrosterone and 19-noretiocholanolone in human urine subsequent to boar consumption using positive-ion LC-ESI-MS-MS. The detection of these steroids is generally used to confirm exogenous administration of 19-nortestosterone (nandrolone). However, a (false) positive result can be obtained from an athlete who ate pork meat. In a subsequent study [65], endogenous 19-norsteroids in boar meat were identified and quantified. 

Norpramin desipramine. norsynephrine topamine. m-norsynephrine norfenefirine. 19-nortestosterone nandrolone. nortriptyline [ban, inn] (nortriptyline hydrochloride [jan, usan[ desitriptyline Aventyl Pamelor and many other names) is an active metabolite of amitryptyline, one of the... 

Also known as endogenous in male horses and prohibited as a doping agent is 19-nortestosterone (nandrolone Figure 2.1). Kim et al. (2000a) validated an LC-MS-MS method for the detection and quantitation of three different commercially available esters, but 19-nortestosterone esters are rapidly hydrolyzed in horse plasma, which limits the usefulness of this method in racehorse doping control. 

FHERBOLICO (Nandrolone Ciclohexilpropionate) 50 mg x 3 injections (one amp each). A Spanish steroid derivative of 19-Nortestosterone. It is similar in action to Durabolin and is used in a dose of 100-200 mg weekly. Also, Anabolin and Nandrocot. 

Nandrolone phenpropionate 19-Nortestosteronephenylpropionate Norethandrolone 17 -Ethyl-l 9-nortestosterone... 

Nandrolone phenpropionate and nandrolone decanoate are esters of 19-nortestosterone, as shown in Figure 45.10, that when administered IM, slow in vivo hydrolysis of the ester occurs releasing free 19-nortestosterone over a prolonged period. Nandrolone deoanoate is the longer-acting ester intended for deep IM injeotion, preferably into the gluteal muscle, in the treatment of anemia assooiated with renal insuffioienoy. Nandrolone phenpropionate has a shorter duration of action than the deoanoate and is used in the treatment of metastatio breast cancer in women. 

Joos, P.E. Van Ryckeghem, M. Liquid chromatography-tandem mass spectrometry of some anabolic steroids, Anal.Chem., 1999, 71,4701-4710. [taleranol estriol trenbolone boldenone fluoxymesterone nortestosterone nandrolone methylboldenone zeranol estrone ethinyl estradiol diethylstUbestrol ... 

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