N-Vinylpyrrolidinone

Acrylamide copolymers designed to reduce undesired amide group hydrolysis, increase thermal stability, and improve solubility in saline media have been synthesized and studied for EOR applications. These polymers still tend to be shear sensitive. Acrylamide comonomers that have been used include 2-acrylamido-2-methylpropane sulfonate, abbreviated AMPS, (1,321-324), 2-sulfo-ethylmethacrylate (325,326), diacetone acrylamide (324, 326), and vinylpyrrolidinone (327,328). Acrylamide terpolymers include those with sodium acrylate and acrylamido-N-dodecyl-N-butyl sulfonate (329), with AMPS and N,N-dimethylacrylamide (330), with AMPS and N-vinylpyrrolidinone (331), and with sodium acrylate and sodium methacrylate (332). While most copolymers tested have been random copolymers, block copolymers of acrylamide and AMPS also have utility in this application (333). 

The observation that the quaternary ammonium monomer content of MDTHD.-DMAEMA and DMAEMA CH3C1 DMAEMA copolymers had little effect on their silica fines stabilization properties of prompted an investigation of nonionic polymers as mineral fines stabilizers (17,18). A series of N-vinylpyrrolidinone (NVP) copolymers with DMAEMA have been studied. Results are summarized in Table VII. 

Nonionic copolymers of N-vinylpyrrolidinone also functioned as mineral fine particle stabilizers. 

Nitroalkane expl N-vinylpyrrolidinone 100, divinylbenzene 1.0 0.3 parts azodiisobutyro-... 

Polyquatemium-11 is the copolymer of N-vinylpyrrolidinone and dimethyl-aminoethyl methacylate quatemized with dimethylsulfate (20). It is used widely but provides litde hold to the hair. Its primary advantage is its ability to improve the ease of wet combing and control static while giving a light set hold. 

Copolymers of N-vinylpyrrolidinone and vinyl acetate were used by Bayer and Geckeler for the synthesis of peptides With symmetric anhydrides as coupling... 

Matyjaszewski et al. first used initiators bearing an unsaturated group for the ATRP process of styrene. In 1998, they [318] used vinyl chloroacetate as the initiator for the ATRP of styrene. As VAc was unreactive towards styrene in radical copolymerization, vinyl chloroacetate was able to initiate the ATRP of styrene (Scheme 65). The resulting PS macromonomers, with molar mass ranging from 5 x 103 to 15 x 103 gmol, were copolymerized with N-vinylpyrrolidinone. The amphiphilic copolymers obtained were used as hydrogels. 

Polypropylene fumarate (PPF) has been in development since the mid-1990s as an injectable, absorbable bone cement with tissue engineering potential. In a 5-week in vivo study in rats, a PPF-based composite crosslinked with N-vinylpyrrolidinone showed good biocompatibility with bone ingrowth and no inflammatory response. Peter and co-workers provide an extensive review of the early development of PPF composite materials, including information about its synthesis, crosslinking, degradation, and... 

Matyjaszewski, K., et al. (1998). Hydrogels by atom transfer radical polymerization. I. poly(N-vinylpyrrolidinone-g-styrene) via the macromonomer method. J. Polym. Sci., Part A Polym. Chem., 36(5) 823-830. 

Poly (N-vinylpyrrolidinone) has many uses in biotechnology and medicine. Here we review our recent work on materials based on this polymer that have applications in drug release or as potential mitogens. The synthesis of crosslinked PNVP hydrogels and highly branched polymers is covered. 

PoIy(N-vinylpyrrolidinone) (PNVP) has been used in medical applications for many years. Its history can be traced back to the Second World War where in its un-crosslinked form it was used as a blood plasma expander (I). This un-crosslinked PNVP when added to iodine forms a complex, in solution this complex is better known as Povidone-iodine or by its trade name Betadine , a surgical antiseptic. PNVP is also used as a binder in many pharmaceutical tablets as low molecular weight PNVP can be removed from the body by the kidneys. These polymers have also been investigated for use as wound dressings, drug... 

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