Muscle spasm vitamin

Lack of sufficient vitamin D causes faulty bone mineralization as previously described. The symptoms of vitamin D deficiency are the same as for calcium deficiency—tingling, muscle spasms, and numbness. Using mineral oil, barbiturates, or cholestyramine, or abusing alcohol can cause vitamin D deficiency. So can fiver or kidney disorders, or certain bowel prob-... 

Observational studies The effect of daily therapy with lyg alfacalcidol for 6 months on musculoskeletal function in elderly patients with reduced bone mass has been examined. Adverse effects reported included epigastric pain, nausea, vomiting, agitation, chest pain, asthenia, dehydration, malaise, muscle spasm, pruritus and gastroenteritis. No serious adverse reactions or hypercalcaemia was observed [35 -]. No adverse events were associated with vitamin... 

Endocrine A rare case of hypoparathyroidism in a 12-year-old child receiving (11.1 mCi) therapy for Graves disease was reported [26 ]. Symptoms of shortness of breath, paraesthesias in extremities, muscle spasms, bone pains, dysphagia, diarrhoea, restlessness, hypocalcemia, hyperphosphatemia and PTH (low-normal range) occurred post RAI. Compounding factors in this case were use of steroids to treat asthma and deliberate vitamin D deficiency. 

A tasteless, odorless, water soluble salt of calcium. It may be administered intravenously for the relief of tetany, caused by an abnormal decrease in blood serum calcium and characterized by cramplike involuntary muscle spasm. Also, calcium gluconate is used as a food additive, buffer, and firming agent, and in some vitamin tablets. 

After the plasma Mg levels had decreased, plasma calcium levels began to drop. The drop in plasma Ca was moderate compared with that in Mg, Plasma Ca levels decreased even though the subjects were receiving adequate amounts of calcium and vitamin D. Neuromuscular symptoms developed after about 4 weeks of the diet. These symphims included tetany, lack of reflexes, tremors, and muscle lAreak-ness. Tetany may be mild, as in mouth twitches, or more severe, as in painful spasms. Hypocalcemia produces a tetany similar to that produced by Mg defi cicncy however. Mg deficiency induced tetany can occur with normal serum calcium levels. The tetany of Mg deficiency can be reversed by administration of Mg but not calcium. Tetany can result from low concentrations of Ca or Mg in the extracellular fluids which surround the nerves) or from an alkaline pH. Low potassium levels in the extracellular fluids, however, do not result in tetany. 

Pathological syndromes may result in muscular spasm, as seen in the exertional myopathies, or weakness, as seen in hyperkalemic periodic paralysis (HYPP). Similarly, infectious diseases may result in muscular rigidity (C. tetani infection (tetanus)) or paralysis (C. botulinum intoxication (botulism)). Overt rhabdomyolysis may result from the ingestion of the coccidiostats monensin, rumensin and lasalocid, or one of a number of plant mycotoxins. Dietary deficiencies of selenium or vitamin E have also been described as having severe deleterious effects on skeletal muscle health. 

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