Micro total analytical systems

Lu H, Schmidt MA, Jensen KF (2001) Photochemical Reactions and On-Line UV Detection in Microfabricated Reactors. Lab Chip 1 22-28 Manz A, Harrison DJ, Verpoorte EMJ, Fettinger JC, Ludi H, Widmer HM (1991) Miniaturization of Chemical-Analysis Systems - A Look into next Century Technology or just a Fashionable Craze. Chimia 45 103-105 McCreedy T (1999) Reducing the Risks of Synthesis. Chem Ind 15 588-590 McCreedy T (2000) Fabrication Techniques and Materials Commonly Used for the Production of Microreactors and Micro Total Analytical Systems. Trac Trends Anal Chem 19 396-401... 

Zourob, M. Mohr, S. Fielden, P. R. McDonnell, M. B. Goddard, N. J., Small volume refractive index and fluorescence sensor for micro total analytical system (p TAS) applica tions, Sens. Actuators B 2003, 94, 304 312... 

T. McCreedy, Fabrication techniques and materials commonly used for the production of microreactors and micro total analytical systems, Trends Anal. Chem., 19 (2000) 396-401. 

Shoji S, Esashi M (1995) Irnvan den Berg A, Bergveld P (eds) Micro total analytical systems. Kluwer Academic Publishers, Dordrecht, p 165... 

Microfluidics and miniaturization hold great promise in terms of sample throughput advantages [100]. Miniaturization of analytical processes into microchip platforms designed for micro total analytical systems (/i-TASs) is a new and rapidly developing field. For SPE, Yu et al. [123] developed a microfabricated analytical microchip device that uses a porous monolith sorbent with two different surface chemistries. The monolithic porous polymer was prepared by in situ photoinitiated polymerization within the channels of the microfluidic device and used for on-chip SPE. The sorbent was prepared to have both hydrophobic and ionizable surface chemistries. Use of the device for sorption and desorption of various analytes was demonstrated [123]. 

Mercury him electrode Micro-total analytical system Molecularly imprinted polymer Multiple linear regression Multiwall carbon nanotube Collection efficiency Number of electrons transferred Normal pulse... 

The so-called micro-total analytical systems (/tTAS) can integrate sample handling, separation, and detection on a single chip [9]. Postcapillary reaction detectors can be incorporated as well [10]. Fluorescence detection is the most common method employed for these chip-based systems. A commercial instrument (Agilent 2100 Bioanalyzer) is available for DNA and RNA separations on disposable chips using a diode laser for LIF detection. In research laboratories, polymerase chain reaction (PCR) has been integrated into a chip that provides size separation and LIF detection [11]. 

G.M. Greenway, S.J. Haswell, P.H. Petsul, Characterisation of a micro-total analytical system for the determination of nitrite with spectrophotometric detection, Anal. Chim. Acta 387 (1999) 1. 

Cullen, C.J., et al. Rapid phase space surface generation using an integrated microfabricated device reaction detection system and automated control, in Micro Total Analytical Systems 2006 The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2006, Tokyo Society for Chemistry and Micro-Nano Systems. 

See also Capillary Electrophoresis Overview. Mass Spectrometry Overview Principles. Micellar Electroki-netlc Chromatography. Micro Total Analytical Systems. 

The so-caUed micro-total analytical systems (mTAS) can integrate sample handling, separation, and detection on a... 

T. McCreedy, Rapid prototyping of glass and PDMS microstructures for micro total analytical systems and micro chemical reactors by microfabrication in the general laboratory. Anal Chim. Acta 2001, 427, 39 3. 

Lab-on-valve , Lab-on-chips , Micro Total Analytical Systems (p-TAS) or Micro Electro Mechanical Systems (MEMS) that operate on micro- and nanometer scales are good examples of new trends and achievements in the area of instrumentation. These enable complex processes such as sampling, reagent addition, calibration, temperature control, and analysis, to be incorporated into... 

The bulkiness of optical sensor instrumentation has prevented - so far - the use of optical chemical sensors ("optodes") in micro total analytical systems (p-TASs) This is going to change in the next future Three kinds of approaches toward optode miniaturization are presented which appear promising in context with p-TAS schemes The following are considered to hold particular promise... 

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