Meningitis, Neisseria

Meropenem (Merrem IV) inhibits syndiesis of die bacterial cell wall and causes die deadi of susceptible cells. This drug is used for intra-abdominal infections caused by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and odier susceptible organisms Meropenem also is effective against bacterial meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Hemophilus influenzae. 

The treatment of bacterial infections of the central nervous system highlights a number of important therapeutic considerations. Bacterial meningitis is caused by a variety of bacteria although their incidence varies with age. In the neonate, E. coli and group B streptococci account for the majority of infections, while in the preschool child H. influenzae is the commonest pathogen. Neisseria meningitidis has a... 

Bacterial meningitis is the most common cause of CNS infections. An epidemiologic review of bacterial meningitis in 1995 revealed that Streptococcus pneumoniae (pneumococcus) was the most common pathogen (47%), followed by Neisseria... 

Neisseria meningitides 2.27/2081 (70) Communicable meningitis sometimes fatal. Contains abundant simple sequence contingency loci... 

CNS infections may be caused by a variety of bacteria, fungi, viruses, and parasites. The most common causes of bacterial meningitis include Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes, and Haemophilus influenzae. 

Bacterial meningitis (pediatric patients 3 months of age or older only) Bacterial meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae ( -lactamase and non- -lactamase-producing strains), and Neisseria meningitidis. 

Meningococcal vaccines Purified surface polysaccharide antigens of one or more strains of Neisseria meningitidis Active immunization against Neisseria meningitidis (can cause meningitis and septicaemia)... 

Neisseria meningitidis (meningococcus) Meningitis Penicillin G 3rd-generation cephalosporin... 

Humphries, H.E., Triantafilou, M., Makepeace, B.L., Heckels, J.E., Triantafilou, K., Christodoulides, M. Activation of human meningeal cells is modulated by lipopolysaccha-ride (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling. Cell Microbiol 7 (2005) 415-430. 

Neisseria gonorrhoeae and Neisseria meningitides are pathogenic for humans in which they cause gonorrhea and meningitis. Both of these organisms, which infect human mucosal surfaces, elaborate a highly... 

Benzylpenicillin achieves peak CSF levels that are reliable for treating sensitive strains of Streptococcus pneumoniae and Neisseria meningitidis but not Haemophilus influenzae and therefore cefotaxime or ceftriaxone are more reliable for suspected H. influenzae meningitis. 

Other indicalions First-year colle students living in dormitories microbiologists who are routinely exposed to isolates of Neisseria meningitids, military recruits and persons who travel to or live in countries in which meningococcal disease is hyperendemic or epidemic (eg, the "meningitis belt" of sub-Saharan Africa duringthe dry season pecember-June]), particularly... 

A series of vaccines against Haemophilus influenzae, started at two months of age, has greatly reduced the incidence of that form of meningitis. Vaccines also exist against Neisseria meningitidis and Streptococcus pneumoniae bacteria, but these vaccines are only recommended for those people who have particular susceptibility to those organisms, due to certain immune deficiencies, lack of a spleen, or sickle cell anemia. 

---