Medial preoptic nucleus

Malinina, E., Druzin, M. 8r Johansson, S. (2005). Fast neurotransmission in the rat medial preoptic nucleus. Brain Res. 1040, 157-68. 

A variety of chemically-identified neurons within the ARC receive both indirect (extrinsic) and direct (intrinsic) enkephalinergic neuronal input (Magoul et al., 1993) suggesting a role for enkephalin in the neuroendocrine regulation of pituitary hormone secretion. Enkephalin-IR perikarya in the bed nucleus of the stria terminalis, medial preoptic nucleus, periventricular nucleus and dorsomedial nucleus all provide extrinsic input to the rostral ARC, whereas intrinsic enkephalin neurons connect the rostral and caudal portions of the ARC (Magoul et al., 1993). Enkephalin-IR neurons innervate TH-IR neurons (perikarya and dendrites) in the DM-ARC (but not in the VL-ARC), (5-endorphin neurons in the VL-ARC, and NPY neurons in the ventromedial ARC (Magoul et al., 1994). There are symmetrical synaptic connections between enkephalin axon terminals and POMC perikarya in the ARC (Zhang et al., 1987), and reciprocal synaptic associations with NPY neurons in the ventromedial ARC (Li et al., 1993). 

Agonists and antagonists of delta opioid receptors do not alter PHDA neuronal activity (Manzanares et al., 1993). No information is available regarding the effects of delta opioid receptor activation or blockade on the activities of IHDA or PeVDA neurons in the rostral periventricular nucleus and medial preoptic nucleus. 

The compact part of the medial preoptic nucleus is negative for substance P (see Fig. 7 of Halliday etal, 1995, in which this structure is visible but not labeled). 

Mo5DL motor trigeminal nucleus, dorsolateral part 56-57 Mo5VM motor trigeminal nucleus, ventromedial part 56-57 Mol molecular layer of the dentate gyrus 35, 79, 87, 106 mp mammillary peduncle 39-43, 80-81, 94-95 MPA medial preoptic area 18-23, 80-81, 93-97 MPB medial parabrachial nucleus 54-60, 83-84, 99-101 MPBE medial parabrachial nucleus external part 56-57 MPn medial pontine nucleus 51 MPO medial preoptic nucleus 23-24, 80, 92-97 MPOC medial preoptic nucleus, central part 21-22, 80 MPOL medial preoptic nucleus, lateral part 18-22 MPOM medial preoptic nucleus, medial part 21-22 MPT medial pretectal nucleus 38-41, 80, 109-110 MRe mammillary recess of the 3rd ventricle 36-38, 79 MRVL medial rostroventrolateral medulla 67-68 MS medial septal nucleus 13-18, 79-80, 103-108 MSO medial superior olive 54-60, 90... 

Preoptic region and hypothalamus Lateral preoptic area Medial preoptic area Medial preoptic nucleus Magnocellular preoptic nucleus Suprachiasmatic nucleus Supraoptic nucleus Anterior hypothalamic area Lateral hypothalamic area Periventricular nucleus Paraventricular hypothalamic nucleus Arcuate nucleus Dorsal hypothalamic area Ventromedial hypothalamic nucleus Dorsomedial hypothalamic nucleus Compact part Tuber cinereum Posterior hypothalamic area Premammillary nucleus Supramammillary nucleus Medial mammillary nucleus Lateral mammillary nucleus... 

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