Mean cell hemoglobin concentration

Mean cell hemoglobin concentration (MCHC) Iron Studies Serum iron 33.4-35.5 g/dL (334-355 g/L) Hemoglobin divided by the hematocrit also low in iron-deficiency anemia. 

G) reductions, - 10%, in hemoglobin and mean cell hemoglobin concentration anemia) ... 

MCV, mean cell volume MCHC, mean cell hemoglobin concentration SI, serum iron TIBC, transferrin iron-binding capacity. 

Gd gestational day (Gl) = gastric intubation (GO) = gavage in oil Hemato - hematological incr. = increased IPTPP = isopropyl triphenyl phosphate LD = lethal dose, 50% kill LOAEL = lowest-observed-adverse-effect level M = male MCV = mean corpuscular volume MCHC = mean corpuscular hemoglobin concentration mo = month(s) Musc/skel = musculoskeletal NOAEL = no-observed-adverse-effect level NS = not specified NTE = neurotoxic esterase RBC red blood cell Resp = respiratory TBEP = tributoxyethyl phosphate TBP = tributyl phosphate TMP = trimethyl phosphate TNBP = tri-n-butyl phosphate TOP = trioctyl phosphate wk = week(s) x = times yr = year(s). 

F, female M, male MCH, mean corpuscular hemoglobin MCHC, mean corpuscular hemoglobin concentration MCV, mean corpuscular volume RBC, red blood cell RDW, red blood cell distribution TIBC, total iron-binding capacity. 

Patients with this abnormality suffer from mild hypochromic anemia with microcytosis and signs of hemolysis a highly characteristic property is the 2- to 3-fold increase in the relative production of Hb-Aa. The Hb-level may vary between 7.5 and 11.5 g/100 ml. Anemia is the most common disturbance followed by hepatomegaly, gall stones, jaundice, splenomegaly, and others (G5). The red blood cell count varies between 5.5 and 7,5 million/mm with mean cell volumes (MCV) of 55-80 and mean cellular hemoglobin concentrations (MCHC) of 25-30%. The peripheral blood film shows hypochromia and microcytosis,... 

Both the hematocrit values and the red cell counts (A) show much the same story. When these values were used to compute the mean corpuscular hemoglobin concentration (Figure 3) and the mean cell volumes (Figure 4) it was found that indeed a microcytic hypochromic anemia had been produced at the lowest iron intake levels.- However, the effect was much more pronounced when 20% protein was fed than when the diet contained 10% casein. 

When rats were exposed to 5, 25, or 77 ppm 2-butoxyethanol 5 days per week, 6 hours per day, for 13 weeks, decreased red blood cell count was observed at 77 ppm in males and females females also exhibited decreased hemoglobin and mean corpuscular hemoglobin concentration at 77 ppm (Dodd et al. 1983). Thus, 25 ppm is the NOAEL for hematological effects in rats after intermediate-duration inhalation exposure to 2-butoxyethanol. Based on this value, an intermediate inhalation MRL of 3.0 ppm for 2-butoxyethanol was calculated as described in the footnote to Table 2-1 and in Appendix A. 

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