Mass spectrometry selectivity

Selected Reaction Monitoring (SRM) Data acquired from specific product ions corresponding to m/z selected precursor ions recorded via two or more stages of mass spectrometry. Selected reaction monitoring can be preformed as tandem mass spectrometry in time or tandem mass spectrometry in space. The term multiple reaction monitoring is deprecated [1],... 

Perri, E., A. Raffaelli, and G. Sindona. OE067 Quantitation of oleuropein in virgin olive oil by ionspray mass spectrometry-selected reaction monitoring. J OE068 Agr Food Chem 1999 47(10) 4156-4160. 

Tanchotikul, U., and T. C. Y. Hsieh. An improved method for quantification of 2 acetyl l pyrroline, a pop-com like aroma, in aromatic rice by high-resolution gas chromatography/ mass spectrometry/selected ion monitoring. J Agr Food Chem 1991 39(5) 944-947. 

Solid Phase MicroExtraction (SPME) is a solvent-free sample preparation method based on the adsorption of analytes directly from an aqueous sample onto a coated fused-silica fiber. Headspace SPME was used in combination with gas chromatography-mass spectrometry/ selective ion monitoring (GC/MS-SIM) to analyze for TCA in wine. 

We have used headspace SPME in combination with GC/mass spectrometry-select ion monitoring to analyze for cork taint impact compounds in wine. Table II lists the analytical parameters that the authors developed for the analysis of TCA in wine (37). 

Fig. 4. GC-ECNI high resolution mass spectrometry selected ion chromatograms of the C10H15C17 formula group, based on the [M-Cl] ion, for beluga blubber samples from Cumberland Sound and Hudson Bay are compared with an extract of an air sample from Alert (NWT) at the northern tip of Ellesmere Island and in the PCA-60 standard. The air sample shows a strong resemblance to the commercial product while the profile in beluga suggests considerable biotransformation. Results from Tomy et al. [78]...

Mol, H. G. J., Van Dam, R. C. J., and Steijger, O. M., Determination of polar organophosphorus pesticides in vegetables and fruits using liquid chromatography with tandem mass spectrometry selection of extraction solvent, J. Chromatogr. A, 1015, 119-127, 2003. 

Practice of Modem Mass Spectrometry Selected Examples.73... 

Friess, S.D. and Zenobi, R. (2001) Protein structure information from mass spectrometry. selective titration of arginine residues by sulfonates. /. Am. Soc. Mass Spectrom., 12, 810-818. 

Quantitation of the Antitumor Agent N-(Phosphonacetyl)-L-aspartic Acid in Human Plasma and Urine by Gas Chromatography-Mass Spectrometry-Selected Ion Monitoring J. Chromatogr. 182(2) 163-169 (1980) CA 93 18827e... 

Determination of Uracil and Thymine and Their Nucleosides and Nucleotides in Picomole Amounts by Gas Chromatography Mass Spectrometry Selected Ion Monitoring Biomed. Mass Spectrom. 6(5) 194-199... 

Schlemmer, F., and Davis, J. M. Quantitation of Amphetamine in Plasma and Cerebrospinal Fluid by Gas Chromatography-Mass Spectrometry-Selected Ion Monitoring Using 6-Methylphenethylamine as an Internal Standard... 

Biomolecule detectors incorporate a biorecognition device capable of selectively recognizing the analyte of interest in connection with a signal transducer and a suitable output device. Transduction methods include a variety of optical (surface plasmon resonance [SPR], fluorescence), electrochemical (voltammetry, impedance, field effect), mechanical (cantilever, surface probe microscopy), and mass-based systems (quartz crystal microgravimetry [QCM], mass spectrometry). Selection of the appropriate transduction system is partially determined by the nature of information sought (quantitative or qualitative), the analyte (concentration, molecular weight), the sample size, and assay timeline. 

Tanchotikul, U. Hsieh, T.C.Y. An Improved Method for Quantification of 2-Acetyl-l-Pyrroline, a "Popcorn"-Like Aroma, in Aromatic Rice by High-Resolution Gas Chromatography/Mass Spectrometry/Selected Ion Monitoring. J. Agr. Food Chem. 1991, 39, 944-947. 

The organization of PMMA-/7-PS-Z7-PMMA triblock copolymers at the interface of immiscible homopolymers [87] was studied by dynamic secondary ion mass spectrometry. Selective labeling of either the two end blocks or the central block provided the contrast necessary to determine the spatial arrangements of the blocks at the interfaces. It was found that the triblock copolymer chains were organized such that the central block preferentially segregated to one homopolymer, whereas the end blocks segregated to the other, thus adopting a hairpin type of conformation as indicated in Fig. 19. 

Thumhofer, S. and Vetter, W., A gas chromatography/electron ionization-mass spectrometry-selected ion monitoring method for determining the fatty acid pattern in food after formation of fattty acid methyl esters, J. Agric. Food Chem., 53, 8896-8903, 2005. 

Chart 5.5 Chemical structures of selected base-damage products identified by gas chromatography/mass spectrometry-selective ion monitoring (CC/MS-S/M) technique [89],... 

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