Major histocompatibility complex restriction

Haselden BM, Kay AB, Larche M Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions. J Exp Med 1999 189 1885-1894. 

Andersen PS, Stryhn A, Hansen BE, Fugger L, Engberg J, Buns S, A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells, Proc. Natl. Acad. Sci. USA., 93 1820-1824, 1996. 

Kohler J, Martin S, Pflugfelder U, et al. Cross-reactive trinitrophenylated peptides as antigens for class II major histocompatibility complex-restricted T cells and inducers of contact sensitivity in mice. Limited T cell receptor repertoire. Eur J Immunol. 1995 25 92-101. 

Naisbitt DJ, Farrell J, Gordon SF, Maggs JL, Burkbart C, Pichler WJ, Pirmohamed M, Park BK. Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation. Mol Pharmacol 2002 62 628-637. 

Tsomides, T.J., Walker, B.D., and Eisen, H.N. (1991) An optimal viral peptide recognized by CD8+T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc. Natl. Acad. Sci. USA 88, 11276-11280. 

McMenamin C, Holt PG The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class Il-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J Exp Med 1993 178 889-899. 

Di Lorenzo, T. P., Graser, R. T., Ono, T., Christianson, G. J., Chapman, H. D., Roopenian, D. C., Nathenson, S. G. and Serreze, D. V. (1998). Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc. Natl. Acad. Sci. USA 95, 12538-12543. 

Buer , Lanoue A, Franzke A, Garcia C, von Boehmer H, Sarukhan A Interleukin 10 secretion and impaired effector function of major histocompatibility complex class ll-restricted cells anergized in vivo. J Exp Med 1998 187 177-83. 

Major Histocompatibility Complex Class I and II Expression. INFy is the principal enhancer of MHC class I expression on many different types of cells. In contrast to type IIFN, it is also an inducer of MHC class II expression in AFCs (mast cells included) and lymphocytes, promoting the activation of class Il-restricted CD4 T cells. These cells are an important target for IFNy, leading to the differentiation of the Th 1 subset and inhibiting the proliferation of Th2 cells. 

BOUR, H PEYRON, E GAUCHERAND, M GARRIGUE, J-L., DESVIGNES, C KAISERLIAN, D., REVILLARD, J.-P. NICOLAS, J.-F. (1995) Major histocompatibility complex class 1-restricted CD8+ T cells and class Il-restricted CD4+ T cells, respectively, mediate and regulate contact sensitivity to dinitro-fluorobenzene. European Journal of Immunology, 25, 3006-3010. 

Buer J, Lanoue A, Franzke A, Garcia C, von Boehmer H, and Sarukhan A. Interleukin 10 secretion and impaired effector function of major histocompatibility complex class ll-restricted T-cells anergized in vivo. J Exp Med 1998 187 177-183. Bucy RP, Xu XY, Li J, and Huang G. Cyclosporin A-induced autoimmune disease in mice. J Immunol 1993 151 1039-1050. Dustin ML, Cooper JA. The immunological synapse and the actin cytoskeleton molecular hardware for T-cell signaling. Nat Immunol 2000 1 23-29. 

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