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Small-cell lymphocytic lymphoma

Indications Acute lymphocytic leukemia, Non-Hodgkin s lymphoma, Small cell lung cancer Category Antineoplastic Topoisomerase 2 inhibitor Half-life 45 minutes... [Pg.555]

CD25 functions as a low-affinity interleukin-2 receptor and may be found on a number of cell types including activated T cells. This antigen is characteristically expressed on hairy cell leukemia, mast cell lesions, and certain T-cell malignancies but may be seen at low levels in certain B-cell lymphomas, particularly small cell lymphocytic lymphoma/chronic lymphocytic leukemia. Targeted therapy is available for this antigen (Ontak). [Pg.158]

INTERPHASE FISH Several recurrent genetic abnormalities identified in small cell lymphocytic lymphoma/chronic lymphocytic leukemia have had a direct relationship to disease progression. These abnormalities are ... [Pg.170]

Of particular interest is the 17p deletion, which is thought to be associated with p53 deletion. This abnormality confers the worse prognosis of any of the above-listed abnormalities but also seems to indicate therapy selection. This abnormality confers fludarabine resistance and there is evidence to suggest that first-line therapy treatment with Campath would be indicated. These abnormalities may be detected in up to 80% of cases of small cell lymphocytic lymphoma. [Pg.170]

CHRONIC LYMPHOCYTIC LEUKEMIA-SMALL CELL LYMPHOCYTIC LYMPHOMA... [Pg.389]

Chronic lympho- + cytic leukemia/ small cell lymphocytic lymphoma + + S S N N N N + S N N S... [Pg.390]

ANLL, acute nonleukocytic leukemia ALL, acute lymphocytic leukemia BM, bone marrow CIcr, creatinine clearance CLL, chronic lymphocytic leukemia CML, chronic myelogenous leukemia DNA, deoxyribonucleic acid HD, Hodgkin s disease HSV, herpes simplex virus IT, intrathecal MDS, myelodysplastic syndrome NHL, non-Hodgkin s lymphoma NSCLC, non-small-cell lung cancer PCP, Pneumocystis carinii pneumonia RNA, ribonucleic acid WBC, white blood cells. [Pg.2299]

European phase II study of rituximab (chimeric anti-CD20 monoclonal antibody) for patients with newly diagnosed mantle-cell lymphoma and previously treated mantle-cell lymphoma, immunocytoma, and small B-cell lymphocytic lymphoma. [Pg.185]

PURPOSE Mantle-cell lymphoma (MCL), immunocytoma (IMC), and small B-cell lymphocytic lymphoma (SLL) are B-cell malignancies that express CD20 and are incurable with standard therapy. [Pg.185]

Tworek JA, Singleton TP, Schnitzer B, et al. Flow cytometric and immunohistochemical analysis of small lymphocytic lymphoma, mantle cell lymphoma, and plasmacytoid small lymphocytic lymphoma. Am J Clin Pathol. 1998 110(5) 582-589. [Pg.185]

Hairy cell leukemia chronic lymphocytic leukemia small cell non-Hodgkin s lymphoma... [Pg.854]

Pediatric acute lymphocytic leukemia, osteogenic sarcoma, Burkitts lymphoma, non-Hodgkin s lymphoma, breast, head, neck, small cell lung, choriocarcinoma, psoriasis, rheumatoid arthritis. [Pg.127]

NHL non-Hodgkin s lymphoma CLL chronic lymphocytic leukemia AML acute myelogenous leukemia CRC colorectal cancer NSCLC non-small cell lung cancer EGFR epidermal growth factor receptor VEGF vascular endothehal growth factor. [Pg.334]

See other pages where Small-cell lymphocytic lymphoma is mentioned: [Pg.158]    [Pg.158]    [Pg.157]    [Pg.170]    [Pg.170]    [Pg.389]    [Pg.79]    [Pg.49]    [Pg.53]    [Pg.126]    [Pg.410]    [Pg.312]    [Pg.315]    [Pg.411]    [Pg.117]    [Pg.364]    [Pg.274]    [Pg.1143]    [Pg.3071]    [Pg.427]    [Pg.165]    [Pg.169]    [Pg.172]    [Pg.181]    [Pg.882]    [Pg.185]    [Pg.509]    [Pg.353]    [Pg.23]    [Pg.543]    [Pg.583]    [Pg.615]    [Pg.622]    [Pg.635]    [Pg.636]   
See also in sourсe #XX -- [ Pg.389 ]



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