Locus coeruleus lesions

Braun, C. M. Pivik, R. T. (1981). Effects of locus coeruleus lesions upon sleeping and waking in the rabbit. Brain Res. 230, 133-51. 

Jones, B. E., Harper, S. T. Halaris, A. E. (1977). Effects of locus coeruleus lesions upon cerebral monoamine content, sleep-wakefulness states and the response to amphetamine in the cat. Brain Res. 124, 473-96. 

Mavridis M, Degryse AD, Lategan AJ, Marien MR, Colpaert FC (1991) Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine in monkeys a possible role for the locus coeruleus in the progression of Parkinson s disease. Neuroscience 41 507-523. 

Hammond, D. L. Proudfit, H. K. (1980). Effects of locus coeruleus lesions on morphine-induced antinociception. Brain Res., 188, 79-91. 

Caballero, A. De Andres, I. (1986). Unilateral lesions in locus coeruleus area enhance paradoxical sleep. Electroencephalogr. Clin. Neurophysiol. 64, 339-46. 

Henley, K. 8r Morrison, A. R. (1974). A re-evaluation of the effects of lesions of the pontine tegmentum and locus coeruleus on phenomena of paradoxical sleep in the cat. Acta Neurobiol. Exp. (Wars). 34, 215-32. 

The junction between the MPOA and lateral preoptic areas is the ventral part of the bed nucleus of the stria terminalis (ventral BST), and excitotoxic lesions disrupt retrieval behaviors and other aspects of maternal behavior in postpartum rats (Numan and Numan, 1996). Strong ventral BST projections to the lateral septum, substantia innominata, PVN, VTA, periaque-dutal gray matter, retrorubral field, and the region surrounding the locus coeruleus (Numan and Numan, 1996). 

Magnuson DS, Staines WA, Marshall KC (1993) Electrophysiological changes accompanying DSP-4 lesions of rat locus coeruleus neurons. Brain Res. 628 317-320. 

Srinivasan J, Schmidt WJ (2004c) Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in rats. J. Neural Transm. 111 13-26. 

Haling JH, Davis IN (1985) Refiograde labeling of locus coeruleus neui ons after lesion-induced sproudng of die coeruleohippocam-pal projecdon. Brain Res 360 384-388. 

Haring JH, Davis JN (1985) Retrograde labeling of locus coeruleus neurons after lesion-induced sprouting of the coeruleohippocam-pal projection. Brain Res 360 384—388. 

NT-3 also prevents degeneration of the noradrenergic neurons of the locus coeruleus following lesions (Arenas and Persson, 1994) and corticospinal cells of layer V (Tetzlaff et al., 1994). Interestingly, neurons in the locus coeruleus die in most degenerative disorders affecting the brain (see Table 6). Thus, the survival-promoting effects of NT-3 in the locus coeruleus (Arenas and Persson,... 

Schwartz, W. J., 1978a, 6-Hydroxydopamine lesions of rat locus coeruleus alter brain... 

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