Liquid Bandage

The wrinkled or corrugated texture of the skin is illustrated in Fig. 2.4. The skin elongates under lateral stress and relaxes when stress is removed. A liquid bandage applied to the skin must be able to adhere to the skin and possess a stress/strain property similar to skin in order to remain attached to the skin. 

An illustration of the application of an emulsified liquid bandage is shown in Fig. 2.5. The microscopic view of this film formation shows microscopic spherical particles coalescing to form a continuous film. The advantage of the emulsion is that it is a waterborne and contains no solvents (i.e., organic solvents) which is preferred over organic solvents for the biocompatible property. 

Narang et al. (2003) reported that 2-octylcyanoacyrlate-based films are excellent microbial barriers. Dermabond Topical Skin Adhesive and Liquid BandageR are... 

The protocol was structured to test the barrier properties of the Liquid BandageR product on rats when challenged with inoculations of bacteria, and the results successful. 

Cyanoacrylates are still used in a variety of medical applications to close wounds and to protect wounds from infection. The 2-octyl ester is used for this purpose because it has fewer hazardous side effects than do the methyl and ethyl esters. Cyanoacrylate is preferred to stitches for closing wounds because it is less likely to become infected and tends to leave fewer scars. For this reason, the compound is often used for cuts on the face, although it cannot be used in the nose or mouth. Consumers can buy cyanoacrylate products such as BandAid brand Liquid Bandage for home use. 

The highly stable product, bis(trimethylsilyl) ether or hexamethyldisiloxane, is produced in many reactions involving trimethylsilyl groups and is often discarded. Its inertness, however, makes for several uses, including liquid bandages such as Cavilon spray, which can be sprayed on broken or tender skin as protection against infection. 

Q. Is an injury that results in treatment with Band-Aid Brand Liquid Bandage considered first aid or medical treatment ... 

After the surgery, Maureen applies Indermil, which is a type of liquid bandage, to Robert s incision sites. Liquid bandages are tissue adhesives that seal surgical or wound incisions on a patient. Stitches and staples are not required and scarring is minimal. The polymer in a liquid bandage is typically dissolved in an alcohol-based solvent. The alcohol also acts as an antiseptic. 

OCA has a longer side chain than butyl cyanoacrylate. It was approved by the FDA for use in the United States in August 1998 for certain types of laceration. Its applications have been expanded and it is now marketed as Dermabond (a trademark of Ethicon, Inc., a Johnson Johnson Company) topical skin adhesive for closure of lacerations and incisions in place of sutures or staples. Later on, a 2-OCA formulated for greater flexibility, Liquid Bandage, was approved for use in the over-the-counter market in the United States for the treatment of minor cuts and abrasions [29]. 

Eye Contact Speed in decontaminating the eyes is absolutely essential remove person from the liquid source, flush the eyes immediately with water by tilting the head to the side, pulling the eyelids apart with the fingers, and pouring water slowly into the eyes do not cover eyes with bandages but if necessary, protect eyes by means of dark or opaque goggles seek medical attention immediately. 

The liquid instilled in the rabbit eye caused slight to moderate pain, conjunctival irritation, and corneal injury that disappeared after 24 hours. When bandaged onto the shaved abdomen of the rabbit for 72 hours, moderate redness, edema, and blistering were observed. ... 

A working knowledge of the physical properties of skin is essential because a liquid dressing (bandage) applied directly to skin will be attached to the skin... 

Sterilization The destruction of all microorganisms in or on a material (as bandages) or liquid (such as irritant fluids)... 

Formulations of 2-octyl cyanoacrylate (Liquid Bandage12), polyvinyl acetate, poly-butryal were successful in rat studies, however, a spray-on bandage is recommended for ease-of-use and, especially for one-hand application such as with a pump-type spray bottle. Aerosol cans are under pressure and may not be allowed to be carried on aircraft. 

As in WWI, WWn recommendations aimed at the relief of symptoms, the control of the lesion, and the prevention of secondary infections and complications. The patient was to be reassured he would not be blinded by the medical practitioner opening his eyelids. Bandages were not to be used. Symptomatic treatment of conjunctivitis was to be treated with irrigation, often with sodium bicarbonate solution (Sorsby, 1939 Cowell, 1939 Bickerton, 1940). Caster oil drops or liquid paraffin drops were thought to be helpful. First-aid treatment with cod-liver oil was felt to do no harm and had been found to give immediate pain relief. It also smoothed comeal roughness and eased lacrimation in... 

Cuts and burns should receive prompt attention. Fires may be extinguished by wet sand, if caused by burning liquids, or by a damp towel or blanket, if due to burning clothing. Acids and alkalies should be removed from the flesh with warm water, and the injured spot immediately covered with a paste made by mixing sodium bicarbonate and the emulsion of lime water and oil the paste may be held in place by cotton and a linen bandage. 

Do not allow contact with air. Wear protective gloves and eye/face protection as specified by the manufacturer/supplier or the competent authority. Keep away from ignition sources such as heat/sparks/open flame. - No smoking. In case of fire, use. .. for extinction. .. appropriate media specified by the manufacturer/supplier or the competent authority if water increases risk. If on skin immerse in cool water/wrap with wet bandages. Store contents under.... .. appropriate liquid or inert gas specified by the manufacturer/supplier or the competent authority. ... 

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