Lipids processing

Salvini, S. et al.. Functional characterization of three clones of the human intestinal Caco-2 cell hne for dietary lipid processing, Br. J. Nutr., 87, 211, 2002. 

Mauro, T.M. et al., Barrier recovery is impeded at neutral pH, independent of ionic effects implications for extracellular lipid processing, Arch. Dermatol. Res., 290, 215,1998. 

Xu, X. Enzymatic production of structured lipids process reactions and acyl migration. Inform 2000, 11 (10), 1121-1131. 

Important information regarding lipid processing behavior... 

Types of lipidations Chemical structures of lipids modifications Biological lipidated processes catalysed by Modification sites Reversibility Cell localizations of lipidated proteins Protein examples... 

Taher et al. (2011,2014b) studied the effect of reaction temperature (35 C-60 C), methanol-to-lipids molar ratios (3 1-15 1), and enzyme loading (10%-50%) on biodiesel production yields from animal fats and microalgae lipids. Process conditions were optimized via response surface methodology. Transesterilication yield of only 40% was obtained when animal fats were used, at 50°C, 200 bar, a 4 1 molar ratio, and a 30% loading of the enzyme (Taher et al., 2011), whereas a conversion above... 

Davies, R.J. (1992a) Advances in lipid processing in New Zealand. Lipid Technol. 4, 6-13. 

Attar PS, Wertz PW, McArthur M, Imakado S, Bickenbach JR, Roop DR (1997) Inhibition of retinoid signalling in transgenic mice alters lipid processing and disrupts epidermal barrier function. Mol Endocrinol 11 792-800... 

Xu X. 2004. Short path distillation for lipid processing. In Lai OM, Akoh CC (editors). Healthful lipid. Champaign, IL AOCS Press, pp. 127-144. 

The modem era of biochemistry and molecular biology has been shaped not least by the isolation and characterization of individual molecules. Recently, however, more and more polyfunctional macromolecular complexes are being discovered, including nonrandomly codistributed membrane-bound proteins [41], These are made up of several individual proteins, which can assemble spontaneously, possibly in the presence of a lipid membrane or an element of the cytoskeleton [42] which are themselves supramolecular complexes. Some of these complexes, e.g. snail haemocyanin [4o], are merely assembled from a very large number of identical subunits vimses are much larger and more elaborate and we are still some way from understanding the processes controlling the assembly of the wonderfully intricate and beautiful stmctures responsible for the iridescent colours of butterflies and moths [44]. 

Permeation process of small molecules across lipid membranes studied by molecular dynamics simulations. J. Phys. Chem. 100 (1996) 16729-16738. 

Although extraction of lipids from membranes can be induced in atomic force apparatus (Leckband et al., 1994) and biomembrane force probe (Evans et al., 1991) experiments, spontaneous dissociation of a lipid from a membrane occurs very rarely because it involves an energy barrier of about 20 kcal/mol (Cevc and Marsh, 1987). However, lipids are known to be extracted from membranes by various enzymes. One such enzyme is phospholipase A2 (PLA2), which complexes with membrane surfaces, destabilizes a phospholipid, extracts it from the membrane, and catalyzes the hydrolysis reaction of the srir2-acyl chain of the lipid, producing lysophospholipids and fatty acids (Slotboom et al., 1982 Dennis, 1983 Jain et al., 1995). SMD simulations were employed to investigate the extraction of a lipid molecule from a DLPE monolayer by human synovial PLA2 (see Eig. 6b), and to compare this process to the extraction of a lipid from a lipid monolayer into the aqueous phase (Stepaniants et al., 1997). 

Chemists and biochemists And it convenient to divide the principal organic substances present m cells into four mam groups carbohydrates proteins nucleic acids and lipids Structural differences separate carbo hydrates from proteins and both of these are structurally distinct from nucleic acids Lipids on the other hand are characterized by a physical property their solubility m nonpolar solvents rather than by their structure In this chapter we have examined lipid molecules that share a common biosynthetic origin m that all their carbons are derived from acetic acid (acetate) The form m which acetate occurs m many of these processes is a thioester called acetyl coenzyme A... 

Peroxide oxidation processes in human organism are one of based phenomena that is responsible for homeostasis. For this reason development and investigation of interaction mechanism between different biomacromolecules and lipids peroxide are important for forming complete picture of functioning of human being as biological system. 

Deficiency of natural AO in the organism brings to intensification of oxidizing processes in lipids and to occurrence in them of oxidation products in quantities that ar e above normal. 

Analysis of neutron data in terms of models that include lipid center-of-mass diffusion in a cylinder has led to estimates of the amplitudes of the lateral and out-of-plane motion and their corresponding diffusion constants. It is important to keep in mind that these diffusion constants are not derived from a Brownian dynamics model and are therefore not comparable to diffusion constants computed from simulations via the Einstein relation. Our comparison in the previous section of the Lorentzian line widths from simulation and neutron data has provided a direct, model-independent assessment of the integrity of the time scales of the dynamic processes predicted by the simulation. We estimate the amplimdes within the cylindrical diffusion model, i.e., the length (twice the out-of-plane amplitude) L and the radius (in-plane amplitude) R of the cylinder, respectively, as follows ... 

Autotrophy A unique form of metabolism foimd only in bacteria. Inorganic compounds (e.g., NH3, N02-, S2, and Fe2+) are oxidized directly (without using sunlight) to yield energy. This metabolic mode also requires energy for C02 reduction, like photosynthesis, but no lipid-mediated processes are involved. This metabolic mode has also been called chemotrophy, chemoautotrophy, or chemolithotrophy. 

The toxic effect depends both on lipid and blood solubility. I his will be illustrated with an example of anesthetic gases. The solubility of dinitrous oxide (N2O) in blood is very small therefore, it very quickly saturates in the blood, and its effect on the central nervous system is quick, but because N,0 is not highly lipid soluble, it does not cause deep anesthesia. Halothane and diethyl ether, in contrast, are very lipid soluble, and their solubility in the blood is also high. Thus, their saturation in the blood takes place slowly. For the same reason, the increase of tissue concentration is a slow process. On the other hand, the depression of the central nervous system may become deep, and may even cause death. During the elimination phase, the same processes occur in reverse order. N2O is rapidly eliminated whereas the elimination of halothane and diethyl ether is slow. In addition, only a small part of halothane and diethyl ether are eliminated via the lungs. They require first biotransformation and then elimination of the metabolites through the kidneys into the... 

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