Lipid phospholipids and

Gn Pig (NS) 11 d 1 hr/d 20 M (decreased cerebral hemisphere and brain stem total lipids and phospholipids) ... 

The advantages of isotopically depleted media are not exclusive to proteins, spectra of lower molecular weight compounds, such as lipids and phospholipids, also benefit from improved mass accuracy in those cases where the isotopic-depletion stragegy can be employed. 

Jones, J. J. Stump, M. J. Fleming, R. C. Lay, J. O. Wilkins, C. L. Strategies and data analysis techniques for lipid and phospholipid chemistry elucidation by intact cell MALDI-FTMS. /. Am. Soc. Mass Spectrom. 2004,15,1665-1674. 

Schiller, J. Suss, R. Amhold, J. Fuchs, B. Lessig, J. Muller, M. Petkovic, M. Spalteholz, H. Zschomig, O. Arnold, K. Matrix-assisted laser desorption and ionization time-of-flight (MALDI-TOF) mass spectrometry in lipid and phospholipid research. Prog. Lipid Res. 2004, 43, 449-488. 

The main action of vitamin E in human tissue is to prevent oxidation of polyunsaturated fatty acids (PUFA), thereby protecting lipid and phospholipids in membranes. Vitamin E interacts syn-ergically with other nutrients, such as vitamin C, selenium, and zinc, which are also involved in the oxidation pathway. The recommended intake is strongly related to the quantity of PUFA consumption. Some studies [454-456] on animal models and epidemiological trials in human suggest... 

Fig. 10. Structures of polymerizable dienoyl ammonium lipid and phospholipids.

Odutuga, A. A., Prout, R. E. S. Fatty acid composition of neutral lipids and phospholipids of enamel and dentin from rat incisors and molars. Arch, oral Biol. 18, 689 (1973)... 

Table 4.4. Content of Glycerol Ethers In Neutral Lipids and Phospholipids Isolated from Bovine Colostrum (Means from Four Swedish Red and White Cows from Days 1 to 5) and Milk (Mean for Four Swedish Red and White Cows from 2nd Wk to 7th Mo)a Week 2 to Month 7.

Morrison, W. R., Jack, E. L. and Smith, L. M. 1965. Fatty acids of bovine milk glyco-lipids and phospholipids and their specific distribution in the diacylglycerophos-pholipids. J. Am. Oil Chem. Soc. 42, 1142-1147. 

Lipids and phospholipids too accumulate at the site of active mineralization. It has been proposed that phosphatidylserine can combine with hydrated metal ions and form a bi-or possibly a tridentate complex417. In forming such a complex, the hydrophilic properties of Ca2+ are decreased and ligands could associate with the... 

All the characteristics expressed in the biological lipids and phospholipids are also expressed in peptide amphiphiles. A variety of alkyl and dialkyl oligoglutamates will be initially discussed as representative of such molecules, which helped in the determination of the structure/assembly relationship (Figure 7.9). The latest advances that demonstrate how using this knowledge, peptide-derived materials were tailored for the construction of functional nanostructures amphiphiles will also be discussed. 

TL Swenson, RW Brocia, AR Tall. Plasma cholesteryl ester transfer protein has binding sites for neutral lipids and phospholipids. J Biol Chem 263 5150-5157, 1988. 

Poulin and Krishnan (1995) developed a method to predict tissue blood PCs for incorporation into physiologically based pharmacokinetic (PBPK) models. Tissue blood partitioning was calculated as an additive function of partitioning into the water, neutral lipids and phospholipids constituent of individual tissues. These were calculated using published values for lipid and water content of tissues and the octanol-water PC of the compounds. Poulin and Krishnan (1998 1999) used this method to predict tissue blood PCs that were subsequently incorporated into a quantitative structure-toxicokinetic model. The prediction of tissue plasma PCs to describe distribution processes and as input parameters for PBPK models has been extensively researched by Poulin and coworkers a great deal of further information can be obtained from their references (Poulin and Theil, 2000 Poulin et al., 2001 Poulin and Theil, 2002a Poulin and Theil, 2002b). 

Chowdhury, N. De Rycke, P. H. (1976). Qualitative distribution of neutral lipids and phospholipids in Hymenolepis microstoma from the cysticercoid to the egg producing adult. Zeitschrift fur Parasitenkunde, 50 151-60. 

Frayha, G. J., Bahr, G. M. Haddad, R. (1980). The lipids and phospholipids of hydatid protoscolices of Echinococcus granulosus (Cestoda). International Journal for Parasitology, 10 213-6. 

The value of this approach is that neutral lipid and phospholipid fractions can be separated very quickly and then examined cleanly separated from each other. Columns as small as 1 g and as large as 200-1000 g have been employed in this type of separation procedure. 

Lysosomes are in effect a cellular waste-bin, and play an important role in the turnover and degradation of cytoplasmic organelles and phago-cytosed particles. They facilitate receptor-mediated endocytosis of many macromolecules from the cell membrane. Lysosomes carry hydrolases that degrade nucleotides, proteins, lipids and phospholipids they also remove carbohydrate, sulphate, or phosphate groups from molecules. Lysosomes store iron, either as soluble ferritin or as products of ferritin degradation, such as haemosiderin. Abnormalities associated with lysosomal function cause a variety of storage disorders such as Tay-Sachs disease [9]. 

A significant variation in milkfat composition can occur in colostrum milk. Ahren et al. (27) analyzed the content of glycerol ethers in neutral lipids and phospholipids isolated from bovine colostrum and milk (Table 10). Lactone content of butter fat has also been determined (Table 11). 

TABLE 10. Content of Glycerol Ethers In Neutral Lipids and Phospholipids Isolated from Bovine Colostrum and Milk (27). 

MacDonald, R., Zhang, W Zhang, J.-P, and Sun, G. Y. (1996). Brain neutral lipids and phospholipids are modified by long-term feeding of beef tallow vs. com oil diets. /. Nufr, 126,1554-1562. 

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