Likely Future Directions

The properties of block copolymers, on the other hand, cannot be calculated without additional information concerning the block sizes, and whether or not the different blocks aggregate into domains. The results of calculations using the methods developed in this book can be inserted as input parameters into models for the thermoelastic and transport properties of multiphase polymeric systems such as blends and block copolymers of immiscible polymers, semicrystalline polymers, and polymers containing various types of fillers. A review of the morphologies and properties of multiphase materials, and of some composite models which we have found to be useful in such applications, will be postponed to Chapter 19 and Chapter 20, where the most likely future directions for research on such materials will also be pointed out. 

The future direction of polyester R D efforts is likely to involve further progress in polyester synthesis given the wide range of potential monomer combinations, new blending technology and the use of advanced functional additives such as nanoclay reinforcements, reactive impact modifiers, anti-hydrolysis agents and chain extenders. 

In addition to the classical approaches described above, scientihc and technological advances in recent years have engendered a number of experimental approaches. Some of these are likely to have major impacts on the future direction of vaccine development. 

For example, the EU recently cleared the herbicide glyphosate (Roundup), which is practically nontoxic to humans, for consumer use. Nevertheless, KEMI has notified importers and distributors that sales of glyphosate to the public will be severely restricted in the future. Faithful to its socialist traditions, the almighty Swedish State attaches no value to the billions of Swedish crowns invested by private homeowners in lawns, flowerbeds, rose gardens, and so on. An appeal to KEMI s decision will most likely be directed to the European Court of Justice. 

However, it should be mentioned that there is a flexible hand-held electrochemical instrument on the market, which can be programmed to be used in a variety of voltammetric/amperometric modes in the field [209]. Although the majority of biosensor applications described in this review were for single analyte detection, it is very likely that future directions will involve development of biosensor arrays for multi-analyte determinations. One example of this approach has been described in an earlier section, where five OPs could be monitored with an array of biosensors based on mutant forms of AChE from D. melanogaster [187]. This array has considerable potential for monitoring the quality of food, such as wheat and fruit. Developments and applications of biosensors in the area of food analysis are expected to grow as consumer demand for improved quality and safety increases. Another area where biosensor developments are likely to increase significantly is in the field of environmental analysis, particularly with respect to the defence of public... 

Apparently, a future direction for studies into climatic instability and related catastrophic events, like Hurricane Katrina (13 years after the most powerful in the history of Miami Hurricane Andrew) in late August 2005 did huge economic damage, completely flooding New Orleans and destroying many buildings, is a search for connections between temperature variations at different scales in different basins... 

Before attempting to assess the likely future of thermodynamics in chemical engineering, it may be useful briefly to recall the past. In chemical engineering, the primary use of thermodynamics was, and still is, concerned with application of the first law (conservation equations), in particular, with energy balances that constitute an essential cornerstone of our discipline. Another primary use was, and still is, directed at description of fluid behavior, as in nozzles, heat engines, and refrigerators. The fundamentals of these important applications were extensively developed in the first third of this century. 

Future directions in the development of polarizable models and simulation algorithms are sure to include the combination of classical or semiempir-ical polarizable models with fully quantum mechanical simulations, and with empirical reactive potentials. The increasingly frequent application of Car-Parrinello ab initio simulations methods " may also influence the development of potential models by providing additional data for the validation of models, perhaps most importantly in terms of the importance of various interactions (e.g., polarizability, charge transfer, partially covalent hydrogen bonds, lone-pair-type interactions). It is also likely that we will see continued work toward better coupling of charge-transfer models (i.e., EE and semiem-pirical models) with purely local models of polarization (polarizable dipole and shell models). 

The future direction of polystyrene R D efforts is uncertain but it is likely that it will continue focusing on lowering manufacturing costs, improving product performance/properties (especially flow/strength balance), reducing the level of residual small molecules left in the product, and developing new applications. 

As to future directions, the problem of the canonical density matrix, or equivalently the Feynman propagator, for hydrogen-like atoms in intense external fields remain an unsolved problem of major interest. Not unrelated, differential equations for the diagonal element of the canonical density matrix, the important Slater sum, are going to be worthy of further research, some progress having already been made in (a) intense electric fields and (b) in central field problems. Finally, further analytical work on semiclassical time-dependent theory seems of considerable interest for the future. 

Based on these future directions, I would like to now address specific policies. 

Each of the questions listed above forms a subsection of this paper. A review of the recent advances in these areas, the requirements for answering the questions, and likely limitations to present solutions are discussed. The final section of the paper integrates these different aspects into a discussion of the risks associated with fault seal evaluation, and attempts to identify the future directions which will help remove the present limitations. 

Current Transform Writing Procedures. At this point we held a project review meeting with the chemists to assess progress and point future directions. The chemists felt they would like to continue to improve the data base, and Dr. Tom Beattie suggested that we send a memo to each Merck chemist asking for volunteers to summarize reactions for transform writing. 

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