Lifestyle intervention

Classic risk factors of atherosclerosis must first and foremost be fought with lifestyle interventions such as diet, physical activity, and smoking cessation. Indeed, and although it effectively relieves angina, simply... 

Diabetes Prevention Program Research Group Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl 3 Med 2002 346 393. 

Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002 346(6) 393 103. 

Nicolson DJ, Dickinson HO, Campbell F, Mason JM. Lifestyle interventions or drugs for patients with essential hypertension a systematic review. 

Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu RT, et al. Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance systematic review and meta-analysis. BMJ. 2007 334 299. 

Clearly, regular exercise remains an important lifestyle intervention with significant survival benefit for all patients with chronic ischemic heart disease, and should be encouraged at every opportunity. A minimum of 30 minutes of walking should be prescribed, preferably on a daily basis. 

Wing RR, Venditti E, )akicic )M, Polley BA, Lang W Lifestyle intervention in overweight individuals with a family history of diabetes. Diabetes Care 21 350-359, 1998. 

Dickinson, H.O. J.M. Mason D.J. Nicolson F. Campbell F.R. Beyer J.V. Cook B. Williams G.A. Ford. Lifestyle interventions to reduce raised blood pressure A systematic review of randomized controlled trials./. Hypertens. 2006, 24, 215—233. 

Balagopal P, Geerge D, Yarandi H, et al. Reversal of obesity-related hypeadipenectinemia by lifestyle intervention—a controlled randomized study in obese adolescents. J Clin Endecrinel Metab 2005 90 6192-6197. 

Corpeleijn E, Feskens EJ, Jansen EH, et al. Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities the SLIM study. Diabetologia. 2006, 49 2392- 401. 

Diabetes Prevention Program Research Group (2002) Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin, N. Engl. J. Med. 346, 393-404. 

Vogeser M, Konig D, Frey I, Predel HG, Parhofer KG, Berg A (2007) Fasting serum insulin and the homeostasis model of insulin resistance (HOMA-IR) in the monitoring of lifestyle intervention of obese persons. Clin Biochem 40 964-968... 

Role of Pioglitazone and Berberine in Treatment of Non-Alcoholic Fatty liver Disease Completed Nonalcoholic fatty liver disease Lifestyle intervention Drug pioglitazone Drag berberine... 

Aleman, G., Torres, N., and Tovar A, R. 2004. Peroxisome proliferator-activated receptors (PPARs) in obesity, and insulin resistance development Rev Invest Clin 56 351-367. An, C., Wang, H., Liu, X. et al. 2009. Serum retinol binding protein 4 is elevated and positively associated with insulin resistance in postmenopausal women. Endocr J 56 987-996. Balagopal, P., Graham, T. E., Kahn, B. B. et al. 2007. Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention Association with subchnical inflammation. J Clin Endocrinol Metab 92 1971-1974. 

A systematic review of nine randomised clinical trials of adequate methodological quality addressed the efficacy and safety of metformin combined with lifestyle interventions in the management of adolescent obesity. The results indicate that among obese adolescents with no associated diseases, the administration of metformin is relatively effective in the short term for reducing BMI. Long-term drug s effects were unknown [22 ]. 

---