Licensing, cost

Other factors include available resources in terms of money and manpower to develop the system in-house, outsource, or purchase from e-clinical proprietary vendors, reliability, flexibility, and security. Some coordinating centers have chosen OSS/FS over proprietary vendors based on the criteria of cost, reliability, flexibility, and security [38]. The rationale is that although both have service comparability, proprietary software licensing costs, both for initial purchases and annual licensing, are significant. 

Here was a shadow under a larger shadow. That the license cost only 100,000 Reichsmarks was understandable, for Farben was merely paying itself a substantial sum for being itself ... 

The all-inclusive model, where the price of the chiral ligand includes not only the manufacturing but also the IP license costs. 

For HCS to be fully accepted by academia, several conditions will need to be fulfilled. Current HCS instruments are closed black boxes and their expensive maintenance contracts do not allow any hardware or software modifications for adaptation to the diverse needs of academic research. Academic research is typically more diversified than pharmaceutical industry research and the instruments need to be more customizable than they are now. In addition, the image and data formats need to be accessible and open. In academia data is shared between collaborators and will be analyzed with various, partly custom-made software. Therefore the data needs to be accessible and open. Lastly, the yearly costs of maintenance contracts and licenses are particularly difficult to finance in academic research that relies heavily on grants. Grants typically do not cover licensing costs or if they do, when the grant runs out, new sources of funding must be found. In reality, those costs must generally be covered by institutional funds. 

Table 1 contains 1995 estimated materials costs for a single photo-thermal detoxification unit chamber fitted with six 15-kW medium-pressure mercury lamps. Labor and licensing costs were not included (D117317, p. 9). 

For a plant in Brazil it is important to verify that the amount to be paid in foreign currency is about 30% of process equipment and engineering, plus licensing costs. Total imports will represent about 13% to 15% of the total investment costs. 

However, in such a high-temperature option, even if the HTE development is a success, a critical issue will remain providing heat at around 900°C, which would require heavy reactor developments for a rather limited market, thus leading to development, engineering and licensing cost amortisation. 

Limited accessibility to all the necessary sources due to licensing costs... 

Predictable license costs Broadly used, mature technology... 

Assumes 14,000 mi/yr driving and 350 mile range (except the Battery EV that has 120 mile range) vehicle costs are adjusted for resale value with monthly payments over 5 years at 4% finance rate insurance, tax, and license costs are excluded. 

The Wasa and PEG. Because of storage and preservation problems, as much as possible of the disconnected wooden material from the Wasa wreck site was left on the seabed during the preliminary work to raise the hull. However, divers brought up some pieces, and in 1958 some small sculptures were treated with PEG. The salvage operation leader and head of the naval dockyard, Edward Clason, got written permission from the license holders Mo och Domsjo AB and Centerwall, dated February 9, 1959, to use the PEG method without license cost. 

You have licensed the use of a hybridoma cell line that secretes tPA monoclonal antibody for the development of your affinity columns (life of column is 3 years). The license costs... 

Operating costs include all fixed cosfs (i.e., fhose independent of how effectively the plant is operated) plus fuel costs (which are nominally directly proportional to the output electric energy from fhe plant). Aside from fuel cosfs, employee costs (salary and benefits) are typically the major component, plus costs of materials and supplies, as well as normal office and facilify expenses, light, heat, and air conditioning. Other fixed costs include taxes, contractor costs, and licensing costs. 

The approach to initially use fuel of the current PWR type (UO2 with enrichment below 5%) provides a readily available, low cost solution, with already established fuel performance, and no ad hoc testing or licensing costs. More advanced fuel and fuel cycle may be introduced when fully developed, licensed, and if justified by market conditions, however IRIS deployment does not depend on these developments. 

The next figure is tree structure diagram showing typical components of life cycle cost for a safety instrumented system. A more comprehensive list would have to show details of all project related costs. For annual costs the model has to includes items such as the service agreement and software licensing costs for the logic solver. A model with suitable... 

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