Lean product design

Products can be designed with a munber of lean attributes. These include  

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This sale and back-lease model is applied by many other pharmaceutical companies. It enables the company to dispose of assets without being forced to lay off employees. The net effect for the industry as a whole is that statistically, the share of outsourcing is increasing. However, the problem of underutilized capacity persists. For a hne-chemical company, the acquisition of an API plant from a pharma company is problematic. Once the supply contract, offered by the pharma company as an incentive for the acquisition, expires, the problem arises as to what the capacity should be used for. This is all the more the case as the plants usually are designed to manufacture just one product and therefore are not truly multipurpose. Last but not least, the plants have been run as cost centers and the implementation of a lean production... 

Because of the frequent use of personal care products by the consumer for hair, body, and skin care, rheological properties are designed to achieve product differentiation. Products are formulated to achieve efficacy within a definite matrix of rheological properties. Certain manufacturers lean toward lower viscosity systems, while others focus on a thicker, richer composition. Regardless of the rheology preference, formulators need to overcome obstacles to achieve robust product design, including variables such as pH and electrolyte concentration. 

Design and Manufacturer/ Lean production 1-Eco efficiency across supply -4,1 -24,5... 

Amid A, Ghodsypour SH, O Brien C (2006) Fuzzy multiobjective linear model for supplier selection in a supply chain. Int J Prod Econ 104(2) 394-407 Amid A, Ghodsypour SH, O Brien C (2011) A weighted max-min model for fiizzy multi-objective supplier selection in a supply chain. Int J Prod Econ 13I(I) I39-I45 Arbos LC (2002) Design of a rapid response and high efBciency service by lean production principles methodology and evaluation of variability of performance. Int J Prod Econ 80 (2) 169-183... 

Nicholas P. Dewhurst says the following in an October 28, 2011, Internet posting titled Product Design Design First, Lean Second ... 

Dewhurst, Nicholas P. Product Design Design First, Lean Second. 2011. Available at http //www.assemblymag.com/articles/89624-product-design-design-first-lean-second. 

Lean construction According to the Lean Construction Institute (2011), lean construction is a new way to design and build capital facilities based on success with lean production management in other engineering disciplines which caused a revolution in manufacturing design, supply, and assembly. ... 

Gautam, N. Singh, N. Lean product development Maximizing the customer perceived value through design change (redesign). International Journal of Production Economics, v. 114, p. 313-332,2008. 

Operates 480 minutes per day, TAKT time is two minutes if customers want two new products designed per month, TAKT time is two weeks. TAKT time sets the pace of production to match the rate of customer demand and becomes the heartbeat of any Lean system. 

From 1910 onward waste filament yam had been chopped into short lengths suitable for use on the machinery designed to process cotton and wool staples into spun yams. In the 1930s new plants were built specifically to supply the staple fiber markets. During World War II the production of staple matched that of filament, and by 1950, staple viscose was the most important product. The new spun-yam oudets spawned a series of viscose developments aimed at matching the characteristics of wool and cotton more closely. Viscose rayon was, after all, silk-like. Compared with wool it lacked bulk, residence, and abrasion resistance. Compared to cotton, it was weaker, tended to shrink and crease more easily, and had a rather lean, limp hand. 

In this chapter, we have presented the foundations of an analytical and simultaneously computational lean and flexible pharmaceutical manufacturing system design approach based on total quality standards. We have discussed why this approach is essential for pharmaceutical product, process, and manufacturing system designs. 

Ranky, P. G, Ranky, G. N., and Ranky, R. G. (2006), Design principles and examples of pharmaceutical manufacturing systems (product, process, lean flexible manufacturing,... 

The design must consider three feed streams and two product streams. The three inlet feed streams are strong reaction gases, weak nitric acid solution and make-up water. Two outlet streams flow from the column. These are a lean reaction gas (tail-gas) stream and red product acid. Absorption of nitrous oxides increases as the temperature is reduced. This effect, together with the exothermic oxidation/ absorption reactions, requires installation of an internal cooling circuit. 

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