Kimura studies

Watari, H., and T. Kimura Study of the adrenal non-heme iron protein (adreno-doxin) by electron spin resonance. Biochem. Biophys. Res. Commun. 24, 106 (1966). 

Other successful combinations have been reported to include molybdenum disulphide in dispersion-hardened silver, 15% molybdenum disulphide with 80% silver and 5% nickel, and 50% molybdenum disulphide, 33.3% silver and 16.7% nickel. Tanaka and Kimura " studied the effect of electric current on the wear of the last of those compacts. They found that the amount of wear increased progressively with increasing amperage, but that the increase represented a change in the size of wear particles rather than an increase in the number of particles. 

S. Kimura, Studies on Energy Metabolism of Diacylglycerol Using Expiration Analysis, The Japanese Society of Nutrition and Food Science, 2002. 

Kimura studied the sensitivity of micro-organisms to antibiotics, panfuran hydrochloride and acetyl panfuran. He used three strains of Staph, aureus, five strains of Shigella Jlexneri, and one strain of E. coli which were isolated from various clinical sources. All strains tested had remained highly sensitive to panfuran hydrochloride and acetylpanfuran but the sensitivity to antibiotics was markedly decreased. 

Katayanagi, M., H. Wakana, and T. Kimura Studies on the Hypotensive Constituents of Morns Root Bark, 1, 12th Annual Meeting of Pharmaceutical Society of Japan, Abstract Papers, 289, April, 1959, Osaka, Japan. 

T Kimura, K Hasegawa, K Funatsu. GA strategy for variable selection m QSAR studies GA-based region selection for CoMFA modeling. J Chem Inf Comput Sci 38 276-282, 1998. 

T. Shiomura, M. Kohno, N. Inoue, Y. Yokote, M. Aki-yama, T. Asanuma, R. Sugimoto, S. Kimura, and M. Abe, Studies in Surface Science and Catalysis Design for Tailor-Made Polyolefins, Kodansha, 327 (1994). 

Kiso M, Mitamura K, Sakai-Tagawa Y, Shiraishi K, Kawakami C, Kimura K, Hayden FG, Sugaya N, Kawaoka Y (2004) Resistant influenza A viruses in children treated with oseltamivir descriptive study. Lancet 364 759-765... 

Higashi, S., Morimoto, K., Satomura, A., Hone, K., Anzai, M., Kimura, K., Takeda, K. Miyazima, T. (1969a). Studies on water-settable cements. Part 9. Examination of the physical properties of water-settable tertiary zinc phosphate. Journal of the Nihon University School of Dentistry, 11, 60-4. 

Thick sedimentary pile from middle Miocene to late Pliocene is exposed in the Oga Peninsula, northern Honshu, Japan (Fig. 1.153). Age of the sedimentary rocks has been determined by microfossil data. Thus, the sedimentary rocks in the Oga Peninsula where type localities of Miocene sedimentary rocks in northern Japan are well exposed have been studied to elucidate the paleoenvironmental change of the Japan Sea (Watanabe et al., 1994a,b). Kimura (1998) obtained geochemical features of these rocks (isotopic and chemical compositions) and found that regional tectonics (uplift of Himalayan and Tibetan region) affect paleo-oceanic environment (oxidation-reduction condition, biogenic productivity). However, in their studies, no detailed discussions on the causes for the intensity and periodicity of hydrothermal activity, and temporal relationship between hydrothermal activity, volcanism and tectonics in the Japan Sea area were discussed. They considered only the time range from ca. 14 Ma to ca. 5 Ma. 

Kage S, Nagata T, Kimura K, et al. 1992. Usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning in forensic toxicological examination A study with animal experiments. Japanese Journal of Forensic Toxicology 10(3) 223-227. 

Kimura and co-workers have made a major contribution to this area with dizinc azamacrocycle complexes characterized including phosphate ester X-ray structures.445,446 They have also studied ligands with pendent alcohol groups.44... 

As already mentioned, larger ring size triazamacrocyclic ligand complexes have also been characterized. The zinc bromide complex of 1,5,9-triazacyclododecane has been characterized as a mononuclear complex with a tetrahedral zinc center.672 Kimura and co-workers have extensively studied zinc complex formation with 1,5,9-triazacyclododecane-based ligands.445,673-676 1,6,11-triazacyclopentadecane forms a zinc complex of the composition Zn3L2Cl6. NMR studies... 

Uemura, R., T. Kameda, K. Kimura, D. Kitamura, and K. Yamasaki (1954), Studies on the Mitsuda-e, a kind of oil-painting, Scientific Papers on Japanese Antiquities and Art Crafts, Vol. 9, pp. 15-21. 

Shibata, S., and M. Kimura Molecular structural studies on compounds... 

Kimura and coworkers have also developed hybrid-type polymersomes composed of polysarcosine-b-PLA ( lactosomes ) [242-243]. The lactosomes are fully biodegradable due to the equipped metabolic pathway for sarcosine and lactic acid. Hence, the lactosome is preferred for in vivo applications rather than for in vitro studies. Indeed, they have demonstrated a potential utility of lactosomes as a contrast agent for in vivo liver tumor imaging [243]. Lactosomes labeled with indocyanine green showed high escape ability from RES, were found to be stable in... 

Figure 2. Structures of typical macrocyclic polyamine compounds studied by Kimura s group.

So far the most potent anti-HIV compounds in vitro among the macro-cyclic polyamines are dinuclear zinc(II) complex of m-xylyl-biscyclen (23) (by Kimura s group) and p-xylyl-biscyclam (30) (by De Clercq s group). They are active against various strains of HIV-1 and HIV-2, while cytotoxicity towards host MT-4 cells are minimal. Their activity against HIV is selective and they are not active against other viruses tested. Hence, the study of their mode of action is not only useful in developing... 

The discovery of in vitro anti-HIV activity of macrocyclic polyamines by the Kimura and De Clercq groups led to development of a new type of effective anti-HIV agents. The results from the studies of the pharmacokinetics and their in vivo efficacy in a SCID-hu Thy/Liv mice are further encouraging indicators of their potential usefulness as new AIDS curing drugs. 

Tamura, Y., T. Maki, H. Yamada, Y. Shimamura, S. Ochiai, S. Nishigaki, and Y. Kimura.1975. Studies on the behavior of accumulation of trace elements in fishes. HI. Accumulation of selenium and mercury in various tissues of tuna. Tokyo Toritsu Eisei Kenkyusho Nenpo 26 200-204. (In Japanese. Translation available from multilingual Serv., Dept. Seer. State Canada, Fish. Mar. Serv. No. 3994, 1977 11 pp.)... 

Tona, M. Kimura, M., Parallel plate ion trap useful for optical studies of microparticles, Rev. Sci. Instrum. 2004, 75, 2276 2279... 

Kimura and Miller [28] have also studied the decomposition of organic fungicides in soil to mercury vapour and to methyl- or ethylmercury compounds and devised methods for the determination of these compounds in the vapours liberated from the soil sample. The mixed vapours of mercury and organomercury compounds is passed successively through bubblers containing a carbonate-phosphate solution to absorb organic... 

T. Kimura, J. J. Ting, and J. J. Huang, Studies on adrenal steroid hydroxylases. Anomalous fluorescence of a tyrosyl residue in adrenal iron-sulfur protein (adrenodoxin), J. Biol. Chem. 247, 4476-4479 (1972). 

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