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Kidneys, ischemia-reperfusion injury

Zahedi K, Soleimani M (2011) Spennidine/spermine-N(l)-acetyltransferase in kidney ischemia reperfusion injury. Methods Mol Biol 720 379-394 Zahedi K, Lentsch AB, OkayaT, Barone S, Sakai N, Witte DP, ArendLJ, Alhonen L, JeU J, Janne J, Porter CW, Soleimani M (2009) Spermidine/spermine-Nl-acetyltransferase ablation protects against liver and kidney ischemia-reperfiision injury in mice. Am J Physiol Gastrointest Liver Physiol 296 899-909... [Pg.74]

Blydt-FIansen, T. D., Katori, M., Lassman, C., Ke, B., Coito, A. J., Iyer, S., Buelow, R., Ettenger, R., Busuttil, R. W. and Kupiec-Weglinski, J. W. (2003). Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury. J. Am. Soc. Nephrol. 14, 745-754. [Pg.185]

Protects against ischemia-reperfusion injury in an experimental model of controlled non-heartbeating donor kidney [174]... [Pg.261]

Williams et al. (1997) described renal ischemia-reperfusion injury in rats. The animals were anesthetized and subjected to 45min of bilateral renal occlusion using atraumatic vascular clamps before renal perfusion was reestablished. After various time interval (up to lweek) blood urea nitrogen, creatinine and myeloperoxidase activity in the kidney were determined. The protective effects of an intracellular adhesion molecule monoclonal antibody were tested. [Pg.124]

Renal ischemia/reperfusion injury in vivo activates caspase-1 and caspase-3 [62, 70]. In a murine model of ischemia/ reperfusion injury, ZVAD-fmk, a pancaspase inhibitor, was shown to attenuate reperfusion-induced DNA damage (as determined by TUNEL assay) and inflammation [65]. Down-regulation of caspase-3 and caspase-8 by siRNA provided protection from acute kidney injury in a mice model of ischemia-reperfusion injury (71). Recent studies by Edelstein et al. [66, 72] help estabhsh a hnk between the inflammatory aspects of the ischemic/reperfusion injury and caspase activation. In these studies it was observed that caspase 1 deficient mice were protected from ischemia-reperfusion... [Pg.160]

Kaushal G, Singh A, Shah S. Identification of caspase (ICE-like proteases) gene family in rat kidney and altered expression in ischemia/reperfusion injury. Am J Physiol 1998 274 F587-F595. [Pg.168]

Park KM, Kramers C,Vayssier-Taussat M, Chen A, Bonventre JV. Prevention of Kidney Ischemia/Reperfusion-induced functional Injury, MAPK and MAPK Kinase Activation, and Inflammation by Remote Transient Ureteral Obstruction. J BiolChem, 2002 277 ... [Pg.169]

ATP depletion, cation shifts and oxygen-derived free radical injury Site of renal ischemia-reperfusion injury A link between proximal and distal tubular injury and recovery Tubuloglomerular feedback and autoregulation Endothelin in ischemia-reperfusion injury Treatment of ischemic acute kidney injury Nephrotoxic injury Cyclosporine... [Pg.174]

The effect of ischemia-reperfusion injury on activity, protein and m-RNA levels of proteins is also studied. For example, the enzymes that are involved in free radical detoxication (catalase, copper-zinc and manganese containing superoxide dismutase and glutatione peroxidase) were studied in rat kidney [101]. This study... [Pg.183]

The FVB-T1E2/GFP mouse, in which the endothelium is fluorescent, has heen used to study morphological changes in the renal microvascular endothelium during ischemia-reperfusion injury in the kidney [169]. Alterations in the cytoskeleton of renal microvascular endothelial cells correlated with a permeability defect in the renal microvasculature as identified using fluorescent dextrans and two-photon intravital imaging. This study demonstrates that renal vascular endothelial injury occurs in ischemic AKI and may play an important role in the pathophysiology of ischemic AKI. [Pg.194]

Gobe G, Willgoss D, Hogg N, Schoch E, Endre Z Cell survival or death in renal tubular epithelium after ischemia- reperfusion injury. Kidney Int 56 1299-1304,1999... [Pg.206]

Ysebaert DK, DeGreef KE, De Beuf A,Van Rompay AR,Vercauteren SR, Persy VP, De Broe ME T cells as mediators in renal ischemia/ reperfusion injury. Kidney Int. 66 491-495, 2004... [Pg.208]

Gulati S, Ainol L, Orak J, Singh AK, Singh i Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. Bio-chim.Biophys.Acta 1182 291-298,1993... [Pg.210]

Gulati S, Singh AK, irazu C, Orak J, Rajagopalan PR, Eitts CT, Singh i ischemia-reperfusion injury biochemical alterations in peroxisomes of rat kidney. Arch.Biochem.Biophys. 295 90-100,1992... [Pg.210]

Linas SL, Shanley PF, Whittenburg D, et al. Neutrophils accentuate ischemia/reperfusion injury in isolated perfused rat kidneys. Am J Physiol 255 F725-F733,1988... [Pg.218]

Kieran NE. Doran PP. Connolly SB, Greenan MC, Higgins DF, Leonard M, Godson C, Taylor CT, Henger A, Kretzler M. Burne MJ, Rabb H, Brady HR (2003) Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Kidney Int 64 480-492... [Pg.67]

O Donnel P, Burne M, Nemoto T, Keane WF, RabbH Direct measurement of renal function in mice with ischemia-reperfusion injury comparison of inulin clearance with serum creatinine, (abstract) J Am Soc Nephrol 11 606A, 2001 Chiao H, Kohda Y, McLeroy P, Craig L, Linas S, Star RA A-melanocyte-stimulating hormone inhibits renal injury in the absence of neutrophils. Kidney Int 54 765-774, 1998... [Pg.105]

See other pages where Kidneys, ischemia-reperfusion injury is mentioned: [Pg.715]    [Pg.811]    [Pg.92]    [Pg.220]    [Pg.183]    [Pg.192]    [Pg.33]    [Pg.715]    [Pg.811]    [Pg.157]    [Pg.157]    [Pg.184]    [Pg.198]    [Pg.694]    [Pg.476]    [Pg.406]    [Pg.66]    [Pg.67]    [Pg.68]    [Pg.79]    [Pg.84]    [Pg.84]    [Pg.88]   
See also in sourсe #XX -- [ Pg.143 ]



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Ischemia reperfusion

Reperfusion

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