International Life Sciences Institute assessment

Guzelian PS, Henry CJ, Olin SS. 1992. Similarities and differences between children and adults Implications for risk assessment. Washington, DC International Life Sciences Institute Press. 

ILSl, A Framework for Estimating Pesticide Concentrations in Drinking Water for Aggregate Exposure Assessments, Workshop Report 5/19/99. International Life Sciences Institute, Washington, DC (1999). 

Since the first description of the BMD approach in health risk assessment of chemicals, the method has been modified and extended by many others. Central in this work was a workshop organized by the International Life Science Institute (ILSl) and reported in Barnes et al. (1995) and a workshop organized by the US-EPA Risk Assessment Eomm resulting in a US-EPA report (US-EPA 1995). No consensus was reached at these workshops on which variation and extension of the BMD approach is most appropriate for the use in human health risk assessment. 

A number of private organizations fund biomonitoring programs for research purposes and to assess exposure at the individual level. The efforts of the American Chemistry Council s Long-Range Research Initiative, the International Life Sciences Institute Health and Environmental Sciences Institute (ILSI-HESI) Biomonitoring Technical Committee, and private laboratories that cater to individual requests to biomonitor for chemicals are highlighted below. 

The methodology in the case study for chronic exposure, as well as several advances in probabilistic assessment methodology for acute exposure (e.g., a person s exposure on a single day), are being incorporated into the Cumulative and Aggregate Risk Evaluation System (CARES) begun in 2000 and being further developed with the International Life Sciences Institute (ILSI) in 2004. 

ILSI (1998). International Life Science Institute Risk Science Institute. Workshop on Aggregate Exposure Assessment. Washington, DC. 

ILSI (2003) Final report Workshop to develop a framework for assessing risks to children from exposure to environmental agents. Washington, DC, International Life Sciences Institute, Risk Science Institute. 

ILSI (2000). Aggregate Exposure Assessment Model Evaluation and Refinement Workshop Report, International Life Sciences Institute (Health and Environmental Sciences Institute), ILSI Press, Washington, DC, USA. 

Robinson, D. The international life sciences institute s role in the evaluation of alternative methodologies for the assessment of carcinogenic risk. Toxicol. Pathol. 1998, 26 (4), 474-A75. 

ILSI (International Life Sciences Institute) (1999) A Framework for Cumulative Assessment An ILSI Risk Science Institute Workshop Report. Washington, DC ILSI Press. ISBN 1-57881-055-8. 

Further, a 2003 guidance document ( Guidance for the safety assessment of botanicals and botanical preparations for use with food and food supplements ) was developed and published by an expert group of the Natural Toxin Task Force of the European Branch of the International Life Sciences Institute (ILSI Europe) and discussed with a wider audience of scientists at a workshop held in May 2002 in Marseille, Erance. 

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